| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
481 | O80397 | 366 | M2K4_ARATH Mitogen-activated protein kinase k... | 279 | 6e-26 | 116 | 30 | 51 | GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009814; P:defense response, incompatible interaction; IMP:TAIR.::GO:0010227; P:floral organ abscission; IMP:TAIR.::GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.::GO:2000038; P:regulation of stomatal complex development; IGI:TAIR.::GO:2000037; P:regulation of stomatal complex patterning; IGI:TAIR. | 482 | Q9SJ61 | 520 | CDPKP_ARATH Calcium-dependent protein kinase ... | 323 | 6e-26 | 117 | 28 | 47 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 483 | O14733 | 419 | MP2K7_HUMAN Dual specificity mitogen-activate... | 278 | 6e-26 | 116 | 31 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004708; F:MAP kinase kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0019903; F:protein phosphatase binding; ISS:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:BHF-UCL.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 484 | Q9QYZ5 | 504 | SMK3_MOUSE Sperm motility kinase 3 OS=Mus mus... | 262 | 7e-26 | 117 | 32 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 485 | Q5YJC2 | 420 | GSK3B_SPECI Glycogen synthase kinase-3 beta O... | 218 | 7e-26 | 116 | 32 | 54 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 486 | P49673 | 337 | KAPC_ASCSU cAMP-dependent protein kinase cata... | 201 | 7e-26 | 115 | 36 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 487 | Q6FV07 | 358 | IPL1_CANGA Spindle assembly checkpoint kinase... | 218 | 7e-26 | 115 | 32 | 56 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW. | 488 | Q54RB2 | 358 | CDK11_DICDI Cyclin-dependent kinase 11 OS=Dic... | 288 | 8e-26 | 115 | 30 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 489 | Q5RJI5 | 778 | BRSK1_MOUSE Serine/threonine-protein kinase B... | 262 | 8e-26 | 119 | 29 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0008021; C:synaptic vesicle; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007409; P:axonogenesis; IMP:UniProtKB.::GO:0051298; P:centrosome duplication; IMP:UniProtKB.::GO:0030010; P:establishment of cell polarity; IMP:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007269; P:neurotransmitter secretion; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB. | 490 | Q9SCU5 | 549 | WNK5_ARATH Probable serine/threonine-protein ... | 283 | 8e-26 | 117 | 32 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043424; F:protein histidine kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048573; P:photoperiodism, flowering; IMP:TAIR. | 491 | Q501V0 | 422 | KPSH1_DANRE Serine/threonine-protein kinase H... | 267 | 8e-26 | 116 | 30 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 492 | B2DD29 | 778 | BRSK1_RAT Serine/threonine-protein kinase BRS... | 262 | 8e-26 | 119 | 29 | 52 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0051298; P:centrosome duplication; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0007269; P:neurotransmitter secretion; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW. | 493 | P27466 | 446 | KCC1_YEAST Calcium/calmodulin-dependent prote... | 272 | 9e-26 | 116 | 30 | 51 | GO:0005737; C:cytoplasm; IPI:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:SGD. | | | | | | | | | | GO:0007165; P:signal transduction; IMP:SGD. | 494 | O62305 | 720 | KCC2D_CAEEL Calcium/calmodulin-dependent prot... | 265 | 9e-26 | 119 | 30 | 50 | GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009931; F:calcium-dependent protein serine/threonine kinase activity; IDA:WormBase.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:WormBase.::GO:0044325; F:ion channel binding; IPI:WormBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0040011; P:locomotion; IMP:WormBase.::GO:0007067; P:mitosis; IMP:WormBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:WormBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 495 | P53681 | 602 | CRK_DAUCA CDPK-related protein kinase OS=Dauc... | 339 | 9e-26 | 118 | 29 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 496 | Q7RM49 | 289 | CDC2H_PLAYO Cell division control protein 2 h... | 289 | 9e-26 | 114 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | | 497 | Q751E8 | 303 | PHO85_ASHGO Negative regulator of the PHO sys... | 296 | 9e-26 | 114 | 31 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 498 | O15530 | 556 | PDPK1_HUMAN 3-phosphoinositide-dependent prot... | 271 | 9e-26 | 117 | 31 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 499 | Q8NG66 | 645 | NEK11_HUMAN Serine/threonine-protein kinase N... | 297 | 1e-25 | 118 | 31 | 51 | GO:0005730; C:nucleolus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0031573; P:intra-S DNA damage checkpoint; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB. | 500 | P18266 | 420 | GSK3B_RAT Glycogen synthase kinase-3 beta OS=... | 218 | 1e-25 | 115 | 32 | 54 | GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:BHF-UCL.::GO:0030877; C:beta-catenin destruction complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:RGD.::GO:0043197; C:dendritic spine; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0005178; F:integrin binding; IPI:RGD.::GO:0035255; F:ionotropic glutamate receptor binding; IPI:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0048156; F:tau protein binding; IDA:RGD.::GO:0050321; F:tau-protein kinase activity; IDA:RGD. | | | | | | | | | | GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; IDA:RGD.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0050774; P:negative regulation of dendrite morphogenesis; IMP:RGD.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:RGD.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:RGD.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0010226; P:response to lithium ion; IEP:RGD. | 501 | P97377 | 346 | CDK2_MOUSE Cyclin-dependent kinase 2 OS=Mus m... | 209 | 1e-25 | 115 | 37 | 59 | GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0000781; C:chromosome, telomeric region; IDA:MGI.::GO:0000793; C:condensed chromosome; IDA:MGI.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:MGI.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.::GO:0000805; C:X chromosome; IDA:MGI.::GO:0000806; C:Y chromosome; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:MGI.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032298; P:positive regulation of DNA-dependent DNA replication initiation; IGI:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:MGI.::GO:0006813; P:potassium ion transport; IGI:MGI. | 502 | Q9JM01 | 593 | CDKL3_RAT Cyclin-dependent kinase-like 3 OS=R... | 290 | 1e-25 | 117 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 503 | Q13546 | 671 | RIPK1_HUMAN Receptor-interacting serine/threo... | 262 | 1e-25 | 118 | 29 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031264; C:death-inducing signaling complex; IDA:BHF-UCL.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:BHF-UCL.::GO:0043235; C:receptor complex; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0070513; F:death domain binding; IPI:BHF-UCL.::GO:0005123; F:death receptor binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.::GO:0007257; P:activation of JUN kinase activity; TAS:BHF-UCL.::GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0060555; P:induction of necroptosis by extracellular signals; IMP:BHF-UCL.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; TAS:BHF-UCL.::GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEP:UniProtKB.::GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; TAS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:BHF-UCL.::GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.::GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.::GO:0070926; P:regulation of ATP:ADP antiporter activity; IMP:BHF-UCL.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IC:BHF-UCL. | 504 | P18431 | 1067 | SGG_DROME Protein kinase shaggy OS=Drosophila... | 218 | 1e-25 | 119 | 30 | 55 | GO:0045169; C:fusome; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase. | | | | | | | | | | GO:0008407; P:chaeta morphogenesis; NAS:FlyBase.::GO:0035293; P:chitin-based larval cuticle pattern formation; IMP:FlyBase.::GO:0009649; P:entrainment of circadian clock; IMP:FlyBase.::GO:0003382; P:epithelial cell morphogenesis; IMP:FlyBase.::GO:0090163; P:establishment of epithelial cell planar polarity; IMP:FlyBase.::GO:0046959; P:habituation; IMP:FlyBase.::GO:0007507; P:heart development; NAS:FlyBase.::GO:0045475; P:locomotor rhythm; NAS:FlyBase.::GO:0043508; P:negative regulation of JUN kinase activity; IMP:FlyBase.::GO:0045879; P:negative regulation of smoothened signaling pathway; IDA:FlyBase.::GO:0045886; P:negative regulation of synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; TAS:FlyBase.::GO:0007219; P:Notch signaling pathway; TAS:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0030707; P:ovarian follicle cell development; IMP:FlyBase.::GO:0045610; P:regulation of hemocyte differentiation; IMP:FlyBase.::GO:0042306; P:regulation of protein import into nucleus; TAS:FlyBase.::GO:0030162; P:regulation of proteolysis; IDA:FlyBase.::GO:0072347; P:response to anesthetic; IMP:FlyBase.::GO:0007367; P:segment polarity determination; IMP:FlyBase.::GO:0035019; P:somatic stem cell maintenance; IMP:FlyBase.::GO:0051124; P:synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0035309; P:wing and notum subfield formation; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; TAS:FlyBase. | 505 | Q23356 | 1096 | MIG15_CAEEL Serine/threonine-protein kinase m... | 276 | 1e-25 | 119 | 28 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IGI:WormBase.::GO:0033563; P:dorsal/ventral axon guidance; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase. | 506 | Q5RAJ5 | 1315 | STK36_PONAB Serine/threonine-protein kinase 3... | 265 | 1e-25 | 119 | 32 | 50 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0007228; P:positive regulation of hh target transcription factor activity; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB. | 507 | P53778 | 367 | MK12_HUMAN Mitogen-activated protein kinase 1... | 292 | 1e-25 | 115 | 30 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004707; F:MAP kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0006975; P:DNA damage induced protein phosphorylation; TAS:ProtInc.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0045445; P:myoblast differentiation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 508 | P41279 | 467 | M3K8_HUMAN Mitogen-activated protein kinase k... | 262 | 1e-25 | 116 | 33 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:InterPro.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 509 | Q6PAD2 | 944 | PLK4_XENLA Serine/threonine-protein kinase PL... | 262 | 1e-25 | 119 | 32 | 52 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB. | 510 | P34331 | 649 | PLK1_CAEEL Serine/threonine-protein kinase pl... | 274 | 1e-25 | 117 | 33 | 51 | GO:0005813; C:centrosome; IDA:WormBase.::GO:0000793; C:condensed chromosome; IDA:WormBase.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0051233; C:spindle midzone; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0007417; P:central nervous system development; IMP:UniProtKB.::GO:0007098; P:centrosome cycle; IMP:UniProtKB.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0007067; P:mitosis; IMP:WormBase.::GO:0007077; P:mitotic nuclear envelope disassembly; IMP:UniProtKB.::GO:0007052; P:mitotic spindle organization; IMP:UniProtKB.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0040038; P:polar body extrusion after meiotic divisions; IMP:WormBase.::GO:0051726; P:regulation of cell cycle; IMP:WormBase. | 511 | Q99558 | 947 | M3K14_HUMAN Mitogen-activated protein kinase ... | 359 | 1e-25 | 119 | 30 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004704; F:NF-kappaB-inducing kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0006955; P:immune response; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome. |
