UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YJL095W

Length:

1478

Number of sequences:

5887

Description:

YJL095W BCK1 SGDID:S000003631, Chr X from 247255-251691, Genome Release 64-1-1, Verified ORF, "Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
361	Q8VHF0	797	MARK3_RAT MAP/microtubule affinity-regulating...	256	3e-27	123	31	51	GO:0005886; C:plasma membrane; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
362	A2Y4B6	424	CDKD1_ORYSI Cyclin-dependent kinase D-1 OS=Or...	294	3e-27	120	31	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
363	O15264	365	MK13_HUMAN Mitogen-activated protein kinase 1...	296	3e-27	120	29	49	GO:0005829; C:cytosol; TAS:Reactome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.::GO:0032755; P:positive regulation of interleukin-6 production; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006970; P:response to osmotic stress; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
364	Q3U1V8	1077	M3K9_MOUSE Mitogen-activated protein kinase k...	282	3e-27	124	28	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
365	P11792	824	SCH9_YEAST Serine/threonine-protein kinase SC...	266	3e-27	123	31	49	GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IGI:SGD.
									GO:0001324; P:age-dependent response to oxidative stress involved in chronological cell aging; IMP:SGD.::GO:0060963; P:positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter; IMP:SGD.::GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IMP:SGD.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:SGD.::GO:0008361; P:regulation of cell size; IMP:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:0047484; P:regulation of response to osmotic stress; IMP:SGD.::GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IMP:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.
366	Q20845	615	PLK3_CAEEL Serine/threonine-protein kinase pl...	269	3e-27	122	31	51	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
367	Q6BS08	875	ATG1_DEBHA Serine/threonine-protein kinase AT...	311	3e-27	124	30	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
368	Q8TD19	979	NEK9_HUMAN Serine/threonine-protein kinase Ne...	282	3e-27	124	28	52	GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
369	Q80XI6	850	M3K11_MOUSE Mitogen-activated protein kinase ...	271	3e-27	123	29	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
370	Q54DC8	1224	Y2350_DICDI Probable serine/threonine-protein...	269	3e-27	124	30	52
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
371	Q00532	357	CDKL1_HUMAN Cyclin-dependent kinase-like 1 OS...	289	4e-27	119	29	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc.
372	B2GUY1	924	PLK4_RAT Serine/threonine-protein kinase PLK4...	267	4e-27	124	28	50	GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
									GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
373	P18161	1155	SPLB_DICDI Dual specificity protein kinase sp...	260	4e-27	124	32	52
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
374	D2H526	1491	CDK12_AILME Cyclin-dependent kinase 12 OS=Ail...	299	4e-27	124	27	45	GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
375	Q04859	622	MAK_MOUSE Serine/threonine-protein kinase MAK...	291	4e-27	122	27	50	GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0001917; C:photoreceptor inner segment; ISS:UniProtKB.::GO:0001750; C:photoreceptor outer segment; IDA:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
									GO:0045494; P:photoreceptor cell maintenance; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
376	Q66HA1	850	M3K11_RAT Mitogen-activated protein kinase ki...	271	4e-27	123	29	49	GO:0005625; C:soluble fraction; IDA:RGD.
									GO:0005524; F:ATP binding; IDA:RGD.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:RGD.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:RGD.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.::GO:0048365; F:Rac GTPase binding; IPI:RGD.
									GO:0008219; P:cell death; IMP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.
377	Q5QN75	355	M2K1_ORYSJ Mitogen-activated protein kinase k...	269	4e-27	119	32	52
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
378	A2VDZ4	893	PLK4_BOVIN Serine/threonine-protein kinase PL...	267	4e-27	123	28	49	GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
									GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
379	Q9C9U2	398	CDKD1_ARATH Cyclin-dependent kinase D-1 OS=Ar...	293	4e-27	120	29	51	GO:0005634; C:nucleus; IDA:TAIR.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
									GO:0030154; P:cell differentiation; TAS:TAIR.::GO:0051726; P:regulation of cell cycle; TAS:TAIR.
380	Q5R9Z7	970	PLK4_PONAB Serine/threonine-protein kinase PL...	268	4e-27	123	29	51	GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
									GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
381	P20793	622	MAK_RAT Serine/threonine-protein kinase MAK O...	291	4e-27	122	27	50	GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0001917; C:photoreceptor inner segment; ISS:UniProtKB.::GO:0001750; C:photoreceptor outer segment; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045494; P:photoreceptor cell maintenance; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
382	Q84VQ3	439	CIPKQ_ARATH CBL-interacting serine/threonine-...	269	4e-27	120	32	52	GO:0005829; C:cytosol; IDA:TAIR.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0007165; P:signal transduction; IEA:InterPro.
383	Q3T0N5	366	MK13_BOVIN Mitogen-activated protein kinase 1...	296	5e-27	119	29	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
384	Q9FJV0	356	M2K6_ARATH Mitogen-activated protein kinase k...	272	5e-27	119	34	51
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
385	Q54MV2	715	MRKB_DICDI Probable serine/threonine-protein ...	292	5e-27	122	30	50
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
386	Q3MJK5	1484	CDK12_RAT Cyclin-dependent kinase 12 OS=Rattu...	299	5e-27	124	27	45	GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IMP:UniProtKB.
387	P51956	506	NEK3_HUMAN Serine/threonine-protein kinase Ne...	274	5e-27	120	33	51	GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; NAS:UniProtKB.
									GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; NAS:UniProtKB.
388	Q68UT7	714	HUNK_PANTR Hormonally up-regulated neu tumor-...	271	5e-27	122	30	52
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
389	P05132	351	KAPCA_MOUSE cAMP-dependent protein kinase cat...	201	6e-27	119	34	58	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0031594; C:neuromuscular junction; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MGI.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.
									GO:0071374; P:cellular response to parathyroid hormone stimulus; IMP:MGI.::GO:0001707; P:mesoderm formation; IGI:MGI.::GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.::GO:0046827; P:positive regulation of protein export from nucleus; IMP:MGI.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0048240; P:sperm capacitation; IDA:UniProtKB.
390	Q7X996	443	CIPK2_ORYSJ CBL-interacting protein kinase 2 ...	288	6e-27	120	30	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0007165; P:signal transduction; IEA:InterPro.
391	P21137	404	KAPC_CAEEL cAMP-dependent protein kinase cata...	201	6e-27	119	35	57
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:WormBase.
									GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.

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