Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL057C
Length:
667
Number of sequences:
5887
Description:
YJL057C IKS1 SGDID:S000003593, Chr X from 330121-328118, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241A4PES0    565   WEE2_PIG Wee1-like protein kinase 2 OS=Sus sc...2990.00001     52     23     40GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
GO:0007143; P:female meiosis; IDA:UniProtKB.::GO:0007128; P:meiotic prophase I; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:InterPro.::GO:0060283; P:negative regulation of oocyte development; IDA:UniProtKB.::GO:0060631; P:regulation of meiosis I; IDA:UniProtKB.
242P59241    397   AURKA_RAT Aurora kinase A OS=Rattus norvegicu...1390.00001     51.6     30     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.
243Q91819    408   AURAB_XENLA Aurora kinase A-B OS=Xenopus laev...1330.00001     51.6     32     46GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0000922; C:spindle pole; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019894; F:kinesin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; ISS:UniProtKB.
244P97711    576   GRK6_RAT G protein-coupled receptor kinase 6 ...1460.00001     52     27     42GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IDA:RGD.
GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; IDA:RGD.::GO:0010360; P:negative regulation of anion channel activity; IMP:RGD.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
245P43250    576   GRK6_HUMAN G protein-coupled receptor kinase ...1460.00001     52     27     44GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.
GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
246P52304    576   POLO_DROME Serine/threonine-protein kinase po...1890.00001     52     25     42GO:0005813; C:centrosome; IDA:FlyBase.::GO:0000940; C:condensed chromosome outer kinetochore; IDA:FlyBase.::GO:0005874; C:microtubule; IDA:FlyBase.::GO:0030496; C:midbody; IDA:FlyBase.::GO:0005635; C:nuclear envelope; IDA:FlyBase.::GO:0000922; C:spindle pole; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase.
GO:0000910; P:cytokinesis; TAS:FlyBase.::GO:0007060; P:male meiosis chromosome segregation; TAS:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0007344; P:pronuclear fusion; IMP:FlyBase.::GO:0035046; P:pronuclear migration; IMP:FlyBase.::GO:0008104; P:protein localization; NAS:FlyBase.::GO:0035044; P:sperm aster formation; IMP:FlyBase.::GO:0007058; P:spindle assembly involved in female meiosis II; IMP:FlyBase.
247Q9DB30    406   PHKG2_MOUSE Phosphorylase b kinase gamma cata...2240.00001     51.6     25     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004689; F:phosphorylase kinase activity; IEA:EC.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
248P32866    714   GPRK2_DROME G protein-coupled receptor kinase...1460.00001     52     27     42GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IMP:FlyBase.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0050830; P:defense response to Gram-positive bacterium; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0002805; P:regulation of antimicrobial peptide biosynthetic process; IMP:FlyBase.::GO:0008589; P:regulation of smoothened signaling pathway; IDA:FlyBase.::GO:0008592; P:regulation of Toll signaling pathway; IGI:FlyBase.::GO:0007224; P:smoothened signaling pathway; IMP:FlyBase.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
249Q13188    491   STK3_HUMAN Serine/threonine-protein kinase 3 ...1910.00001     51.6     24     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
250Q4P5N0    746   STE20_USTMA Serine/threonine-protein kinase S...1380.00001     52     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
251Q6BS08    875   ATG1_DEBHA Serine/threonine-protein kinase AT...1450.00001     52     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
252Q9H093    628   NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS...3100.00001     52     23     37
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
253O70293    576   GRK6_MOUSE G protein-coupled receptor kinase ...1460.00001     52     27     44GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.
GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
254O43283    966   M3K13_HUMAN Mitogen-activated protein kinase ...2900.00001     52     22     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0007254; P:JNK cascade; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
255P18652    752   KS6AA_CHICK Ribosomal protein S6 kinase 2 alp...2180.00002     51.6     26     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.
256P34244    1518   HSL1_YEAST Probable serine/threonine-protein ...1410.00002     52     26     41GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005940; C:septin ring; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000078; P:cell shape checkpoint; TAS:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:SGD.::GO:0046777; P:protein autophosphorylation; IMP:SGD.::GO:0000135; P:septin checkpoint; IGI:SGD.
257Q9ZR79    659   LRK57_ARATH L-type lectin-domain containing r...2930.00002     52     23     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
258Q91XS8    371   ST17B_RAT Serine/threonine-protein kinase 17B...2060.00002     51.2     23     40GO:0015629; C:actin cytoskeleton; IMP:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.
259Q5R7G9    628   NUAK2_PONAB NUAK family SNF1-like kinase 2 OS...3100.00002     52     23     37
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
260Q8SQW2    329   CTK1_ENCCU Probable CTD kinase subunit alpha ...2030.00002     51.2     24     43GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
261O70291    574   GRK4_MOUSE G protein-coupled receptor kinase ...1630.00002     51.6     26     42GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
262Q10056    589   SHK2_SCHPO Serine/threonine-protein kinase sh...2990.00002     51.6     22     39GO:0005739; C:mitochondrion; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0032488; P:Cdc42 protein signal transduction; NAS:PomBase.::GO:0000165; P:MAPK cascade; NAS:PomBase.
263Q9CAU7    606   NEK2_ARATH Serine/threonine-protein kinase Ne...3510.00002     51.6     21     36
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
264Q8BG48    372   ST17B_MOUSE Serine/threonine-protein kinase 1...2060.00002     51.2     23     40GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.
265Q5R8X7    966   M3K13_PONAB Mitogen-activated protein kinase ...2900.00002     52     22     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0007254; P:JNK cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
266P25323    295   MYLKA_DICDI Myosin light chain kinase A OS=Di...1340.00002     50.8     25     42GO:0005737; C:cytoplasm; IDA:dictyBase.
GO:0030898; F:actin-dependent ATPase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004687; F:myosin light chain kinase activity; IDA:dictyBase.
GO:0019933; P:cAMP-mediated signaling; IDA:dictyBase.::GO:0019934; P:cGMP-mediated signaling; IDA:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0050920; P:regulation of chemotaxis; IMP:dictyBase.
267Q9S9V0    484   CDPKV_ARATH Calcium-dependent protein kinase ...3520.00002     51.6     23     37GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009751; P:response to salicylic acid stimulus; IEP:TAIR.
268A7MBB4    966   M3K13_BOVIN Mitogen-activated protein kinase ...2900.00002     52     22     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; IEA:InterPro.
GO:0046777; P:protein autophosphorylation; IEA:InterPro.
269Q9VEZ5    751   IKKB_DROME Inhibitor of nuclear factor kappa-...1580.00002     51.6     25     41GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008384; F:IkappaB kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0019731; P:antibacterial humoral response; IMP:FlyBase.::GO:0051607; P:defense response to virus; IMP:FlyBase.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:FlyBase.::GO:0006963; P:positive regulation of antibacterial peptide biosynthetic process; IDA:UniProtKB.::GO:0030163; P:protein catabolic process; IDA:UniProtKB.::GO:0045088; P:regulation of innate immune response; IMP:FlyBase.::GO:0008063; P:Toll signaling pathway; TAS:FlyBase.
270Q1HKZ5    959   M3K13_MOUSE Mitogen-activated protein kinase ...2900.00002     52     22     37GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
271Q8VBY2    505   KKCC1_MOUSE Calcium/calmodulin-dependent prot...1560.00002     51.6     31     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
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