Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL050W
Length:
1073
Number of sequences:
5887
Description:
YJL050W MTR4 SGDID:S000003586, Chr X from 342522-345743, Genome Release 64-1-1, Verified ORF, "ATP-dependent 3'-5' RNA helicase of the Dead-box family, involved in nuclear RNA processing and degradation both as a component of the TRAMP complex and in TRAMP independent processes; has a KOW domain that shows RNA binding activity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P47047    1073   MTR4_YEAST ATP-dependent RNA helicase DOB1 OS...10730     2218     100     100GO:0005730; C:nucleolus; IDA:SGD.::GO:0031499; C:TRAMP complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034459; F:ATP-dependent 3'-5' RNA helicase activity; IDA:SGD.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0043629; P:ncRNA polyadenylation; IDA:SGD.::GO:0071042; P:nuclear polyadenylation-dependent mRNA catabolic process; IMP:SGD.::GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; IMP:SGD.::GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; IDA:SGD.::GO:0071049; P:nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription; IGI:SGD.::GO:0071051; P:polyadenylation-dependent snoRNA 3'-end processing; IMP:SGD.::GO:0034475; P:U4 snRNA 3'-end processing; IMP:SGD.::GO:0034476; P:U5 snRNA 3'-end processing; IMP:SGD.
2O14232    1117   MTR4_SCHPO ATP-dependent RNA helicase mtr4 OS...10120     1336     65     79GO:0005730; C:nucleolus; ISS:PomBase.::GO:0031499; C:TRAMP complex; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:PomBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0043630; P:ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process; ISS:PomBase.::GO:0071049; P:nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription; ISS:PomBase.::GO:0006364; P:rRNA processing; ISS:PomBase.::GO:0016078; P:tRNA catabolic process; ISS:PomBase.
3Q9CZU3    1040   SK2L2_MOUSE Superkiller viralicidic activity ...9540     1113     56     75GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
4P42285    1042   SK2L2_HUMAN Superkiller viralicidic activity ...9540     1106     56     75GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000460; P:maturation of 5.8S rRNA; IMP:UniProtKB.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.
5O13799    1030   YE02_SCHPO Uncharacterized helicase C17H9.02 ...9580     974     49     71GO:0005730; C:nucleolus; ISS:PomBase.::GO:0031499; C:TRAMP complex; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:PomBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0043630; P:ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process; ISS:PomBase.::GO:0071049; P:nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription; ISS:PomBase.::GO:0006364; P:rRNA processing; ISS:PomBase.::GO:0016078; P:tRNA catabolic process; ISS:PomBase.
6Q23223    1026   MTR4_CAEEL mRNA transport homolog 4 OS=Caenor...9530     907     47     67GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040022; P:feminization of hermaphroditic germ-line; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0042127; P:regulation of cell proliferation; IMP:WormBase.::GO:0040020; P:regulation of meiosis; IMP:WormBase.
7Q15477    1246   SKIV2_HUMAN Helicase SKI2W OS=Homo sapiens (H...9960     599     36     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0055087; C:Ski complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
8O59801    1213   SKI2_SCHPO Putative ATP-dependent RNA helicas...9660     591     37     56GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; ISS:PomBase.::GO:0055087; C:Ski complex; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0003724; F:RNA helicase activity; ISS:PomBase.
GO:0006402; P:mRNA catabolic process; ISS:PomBase.::GO:2000765; P:regulation of cytoplasmic translation; ISS:PomBase.
9P35207    1287   SKI2_YEAST Antiviral helicase SKI2 OS=Sacchar...2187e-32     138     38     58GO:0055087; C:Ski complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; IMP:SGD.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; IMP:SGD.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
10Q9ZBD8    920   HELY_MYCLE Probable helicase helY OS=Mycobact...8902e-87     307     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
11Q10701    906   HELY_MYCTU Probable helicase helY OS=Mycobact...2520.044     41.6     19     38GO:0005618; C:cell wall; IDA:MTBBASE.::GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
12B9DFG3    1171   ISE2_ARATH DEAD-box ATP-dependent RNA helicas...4829e-77     279     37     52GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0010494; C:cytoplasmic stress granule; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0010497; P:plasmodesmata-mediated intercellular transport; IMP:TAIR.::GO:0016441; P:posttranscriptional gene silencing; IMP:TAIR.
13Q4JC00    705   HELS_SULAC Putative ski2-type helicase OS=NBR...4364e-38     156     29     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
14Q97VY9    708   HELS_SULSO Putative ski2-type helicase OS=P2)...5006e-36     149     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
15Q974S1    704   HELS_SULTO Putative ski2-type helicase OS=Sul...4321e-35     149     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
16Q9HJX7    674   HELS_THEAC Putative ski2-type helicase OS=NBR...4344e-35     147     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
17Q97AI2    674   HELS_THEVO Putative ski2-type helicase OS=154...4472e-34     144     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
18Q12WZ6    760   HELS_METBU Putative ski2-type helicase OS=Met...4153e-31     135     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
19Q8TL39    730   HELS_METAC Putative ski2-type helicase OS=C2A...4373e-31     135     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
20A7IB61    723   HELS_METB6 Putative ski2-type helicase OS=Met...4364e-31     135     26     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
21Q9V0A9    715   HELS_PYRAB Putative ski2-type helicase OS=Pyr...4812e-29     129     27     45
GO:0005524; F:ATP binding; IEA:HAMAP.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:HAMAP.
GO:0006281; P:DNA repair; IEA:InterPro.
22Q8PZR7    730   HELS_METMA Putative ski2-type helicase OS=JCM...4133e-29     129     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
23Q465R3    729   HELS_METBF Putative ski2-type helicase OS=Met...4765e-29     128     26     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
24O59025    715   HELS_PYRHO Putative ski2-type helicase OS=NBR...4852e-28     126     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
25P51979    1187   HFM1_YEAST ATP-dependent DNA helicase MER3 OS...4831e-26     121     25     44GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003678; F:DNA helicase activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006268; P:DNA unwinding involved in replication; IDA:SGD.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.::GO:0007129; P:synapsis; IMP:SGD.
26Q0W6L1    740   HELS_UNCMA Putative ski2-type helicase OS=Unc...4221e-26     120     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
27A8MB76    756   HELS_CALMQ Putative ski2-type helicase OS=/ I...4372e-26     120     27     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
28A3MSA1    708   HELS_PYRCJ Putative ski2-type helicase OS=Pyr...5233e-26     119     27     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
29O73946    720   HELS_PYRFU Putative ski2-type helicase OS=Pyr...4853e-25     116     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
30Q5UYM9    799   HELS_HALMA Putative ski2-type helicase OS=B-1...4283e-25     116     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
31Q9U2G0    2145   U520_CAEEL Putative U5 small nuclear ribonucl...2000.0006     48.1     26     46GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0016477; P:cell migration; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0042127; P:regulation of cell proliferation; IMP:WormBase.::GO:0040020; P:regulation of meiosis; IMP:WormBase.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
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