Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL050W
Length:
1073
Number of sequences:
5887
Description:
YJL050W MTR4 SGDID:S000003586, Chr X from 342522-345743, Genome Release 64-1-1, Verified ORF, "ATP-dependent 3'-5' RNA helicase of the Dead-box family, involved in nuclear RNA processing and degradation both as a component of the TRAMP complex and in TRAMP independent processes; has a KOW domain that shows RNA binding activity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q9U2G0    2145   U520_CAEEL Putative U5 small nuclear ribonucl...2000.0006     48.1     26     46GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0016477; P:cell migration; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0042127; P:regulation of cell proliferation; IMP:WormBase.::GO:0040020; P:regulation of meiosis; IMP:WormBase.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
32A2RUV5    1336   HFM1_XENTR Probable ATP-dependent DNA helicas...5345e-25     116     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
33Q9HMV6    783   HELS_HALSA Putative ski2-type helicase OS=(Ha...4479e-25     115     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
34B0R7Q2    783   HELS_HALS3 Putative ski2-type helicase OS=Hal...4479e-25     115     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
35Q3IU46    747   HELS_NATPD Putative ski2-type helicase OS=Nat...4204e-24     112     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
36A2PYH4    1435   HFM1_HUMAN Probable ATP-dependent DNA helicas...4297e-24     112     26     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
37Q54G57    2195   HELC1_DICDI Activating signal cointegrator 1 ...4206e-19     97.1     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
38A6UN73    751   HELS_METVS Putative ski2-type helicase OS=Met...4442e-21     104     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
39E1BNG3    2201   ASCC3_BOVIN Activating signal cointegrator 1 ...2020.000001     56.6     25     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
40F1NTD6    2211   ASCC3_CHICK Activating signal cointegrator 1 ...2020.0001     50.4     24     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
41O75417    2590   DPOLQ_HUMAN DNA polymerase theta OS=Homo sapi...4387e-21     103     25     45GO:0005654; C:nucleoplasm; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003684; F:damaged DNA binding; TAS:ProtInc.::GO:0003887; F:DNA-directed DNA polymerase activity; IDA:UniProtKB.::GO:0043142; F:single-stranded DNA-dependent ATPase activity; IDA:UniProtKB.
GO:0006281; P:DNA repair; TAS:ProtInc.::GO:0006260; P:DNA replication; IEA:InterPro.
42Q8N3C0    2202   ASCC3_HUMAN Activating signal cointegrator 1 ...2020.0001     50.4     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
43E7F8F4    1534   ASCC3_DANRE Activating signal cointegrator 1 ...2030.0001     49.7     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
44Q9VUV9    2142   U520_DROME Putative U5 small nuclear ribonucl...2030.003     45.8     25     48GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.::GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:FlyBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0007067; P:mitosis; IMP:FlyBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:FlyBase.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IMP:FlyBase.
45E9PZJ8    2198   ASCC3_MOUSE Activating signal cointegrator 1 ...2020.00002     52.4     26     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46Q9P7T8    1717   YIW2_SCHPO Uncharacterized helicase C694.02 O...880.0000000000002     79     48     64GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
47O75643    2136   U520_HUMAN U5 small nuclear ribonucleoprotein...4506e-17     90.5     25     43GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005682; C:U5 snRNP; IDA:HGNC.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IDA:HGNC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0000354; P:cis assembly of pre-catalytic spliceosome; IC:HGNC.
48O60072    1935   MUG81_SCHPO Putative helicase mug81 OS=Schizo...4223e-16     88.2     24     44GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:PomBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:2000765; P:regulation of cytoplasmic translation; ISS:PomBase.
49P32639    2163   BRR2_YEAST Pre-mRNA-splicing helicase BRR2 OS...2210.00004     51.6     25     43GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.::GO:0005682; C:U5 snRNP; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IMP:SGD.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0000388; P:spliceosome conformational change to release U4 (or U4atac) and U1 (or U11); IMP:SGD.
50Q2VPA6    1069   HELQ_MOUSE Helicase POLQ-like OS=Mus musculus...4485e-18     93.6     24     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
51Q5JGV6    1125   HELS_PYRKO Putative ski2-type helicase OS=(Th...3881e-17     92.8     25     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:InterPro.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006314; P:intron homing; IEA:UniProtKB-KW.
52Q9YFQ8    735   HELS_AERPE Putative ski2-type helicase OS=100...1730.000000000000001     85.5     29     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
53Q54XN7    1816   Y8827_DICDI Uncharacterized helicase DDB_G027...2200.000000002     65.9     28     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
54Q09475    1714   YP93_CAEEL Uncharacterized helicase C28H8.3 O...1800.000000000000002     85.5     34     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
55Q8IY21    1712   DDX60_HUMAN Probable ATP-dependent RNA helica...2280.00000000004     71.6     27     47GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
GO:1900245; P:positive regulation of MDA-5 signaling pathway; IMP:UniProtKB.::GO:1900246; P:positive regulation of RIG-I signaling pathway; IMP:UniProtKB.::GO:0009615; P:response to virus; IDA:UniProtKB.
56Q9UT24    2176   BRR2_SCHPO Pre-mRNA-splicing factor brr2 OS=S...4240.000000001     66.6     22     40GO:0005829; C:cytosol; IDA:PomBase.::GO:0005681; C:spliceosomal complex; IDA:PomBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.::GO:0005682; C:U5 snRNP; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:PomBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0000393; P:spliceosomal conformational changes to generate catalytic conformation; IGI:PomBase.
57Q58524    1195   HELS_METJA Putative ski2-type helicase OS=JCM...480.5     38.1     35     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:InterPro.::GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.::GO:0006314; P:intron homing; IEA:UniProtKB-KW.
58Q5H9U9    1706   DDX6L_HUMAN Probable ATP-dependent RNA helica...1880.000000003     65.1     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
59P53327    1967   SLH1_YEAST Antiviral helicase SLH1 OS=Sacchar...2110.000000004     65.1     27     50GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006417; P:regulation of translation; IMP:SGD.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
60Q55CI8    2237   HELCL_DICDI Activating signal cointegrator 1 ...2300.000001     56.6     27     47GO:0005681; C:spliceosomal complex; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:dictyBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008380; P:RNA splicing; ISS:dictyBase.
61Q8TDG4    1101   HELQ_HUMAN Helicase POLQ-like OS=Homo sapiens...4500.000000000000005     84     24     42GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
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