Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL050W
Length:
1073
Number of sequences:
5887
Description:
YJL050W MTR4 SGDID:S000003586, Chr X from 342522-345743, Genome Release 64-1-1, Verified ORF, "ATP-dependent 3'-5' RNA helicase of the Dead-box family, involved in nuclear RNA processing and degradation both as a component of the TRAMP complex and in TRAMP independent processes; has a KOW domain that shows RNA binding activity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q9M2E0    498   RH12_ARATH DEAD-box ATP-dependent RNA helicas...1600.59     37.7     23     41GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
122Q9FT73    705   RQL2_ARATH ATP-dependent DNA helicase Q-like ...940.65     37.7     30     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0009378; F:four-way junction helicase activity; IDA:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.
GO:0006310; P:DNA recombination; IC:TAIR.::GO:0006281; P:DNA repair; IC:TAIR.::GO:0006260; P:DNA replication; IEA:InterPro.
123A7TGW7    977   DBP10_VANPO ATP-dependent RNA helicase DBP10 ...1730.76     37.7     25     42GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
124Q5BJS0    1194   DHX30_RAT Putative ATP-dependent RNA helicase...1660.79     37.7     28     43GO:0042645; C:mitochondrial nucleoid; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
125Q9BQ39    737   DDX50_HUMAN ATP-dependent RNA helicase DDX50 ...840.84     37.4     30     48GO:0005730; C:nucleolus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
126Q869P0    908   DDX31_DICDI Probable ATP-dependent RNA helica...1680.84     37.4     26     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
127Q99PU8    1217   DHX30_MOUSE Putative ATP-dependent RNA helica...1660.9     37.4     28     43GO:0042645; C:mitochondrial nucleoid; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
128Q99MJ9    734   DDX50_MOUSE ATP-dependent RNA helicase DDX50 ...840.93     37.4     30     48GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
129Q99J87    678   DHX58_MOUSE Probable ATP-dependent RNA helica...1330.94     37.4     24     46GO:0005737; C:cytoplasm; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0045824; P:negative regulation of innate immune response; IMP:UniProtKB.::GO:0039534; P:negative regulation of MDA-5 signaling pathway; ISS:UniProtKB.::GO:0039536; P:negative regulation of RIG-I signaling pathway; IMP:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; IMP:UniProtKB.::GO:1900245; P:positive regulation of MDA-5 signaling pathway; IMP:UniProtKB.::GO:1900246; P:positive regulation of RIG-I signaling pathway; IMP:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; IMP:UniProtKB.
130A7TGU7    484   DHH1_VANPO ATP-dependent RNA helicase DHH1 OS...1600.98     37     23     38GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
131P41380    391   IF4A3_NICPL Eukaryotic initiation factor 4A-3...1841.1     36.6     26     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
132Q7S9J4    934   DBP10_NEUCR ATP-dependent RNA helicase dbp-10...1741.1     37     27     43GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
133O94445    647   SUV3_SCHPO ATP-dependent RNA helicase suv3, m...1146.1     34.7     25     44GO:0005759; C:mitochondrial matrix; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:PomBase.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000965; P:mitochondrial RNA 3'-end processing; IMP:PomBase.
134Q2H0R2    762   DBP10_CHAGB ATP-dependent RNA helicase DBP10 ...1721.2     37     26     41GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
135A5DQF1    475   RRP3_PICGU ATP-dependent rRNA helicase RRP3 O...1621.2     36.6     23     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
136Q295E6    762   SUV3_DROPS ATP-dependent RNA helicase SUV3 ho...1452.7     35.8     26     45GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003678; F:DNA helicase activity; ISS:UniProtKB.
137Q6C7D2    605   HAS1_YARLI ATP-dependent RNA helicase HAS1 OS...1721.4     36.6     26     44GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
138Q75AA7    1077   MPH1_ASHGO ATP-dependent DNA helicase MPH1 OS...2361.5     36.6     22     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
139Q7L2E3    1194   DHX30_HUMAN Putative ATP-dependent RNA helica...1661.5     36.6     27     43GO:0042645; C:mitochondrial nucleoid; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
140P21693    457   DBPA_ECOLI ATP-independent RNA helicase dbpA ...1901.6     36.2     23     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0043531; F:ADP binding; IDA:EcoCyc.::GO:0005524; F:ATP binding; IDA:EcoCyc.::GO:0034459; F:ATP-dependent 3'-5' RNA helicase activity; IDA:EcoCyc.::GO:0033677; F:DNA/RNA helicase activity; IDA:EcoliWiki.::GO:0019843; F:rRNA binding; IDA:EcoCyc.
GO:0000027; P:ribosomal large subunit assembly; IMP:EcoCyc.
141Q6FNA2    969   DBP10_CANGA ATP-dependent RNA helicase DBP10 ...1711.6     36.6     22     43GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
142Q6CT85    487   RRP3_KLULA ATP-dependent rRNA helicase RRP3 O...1671.7     36.2     22     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
143Q8IYB8    786   SUV3_HUMAN ATP-dependent RNA helicase SUPV3L1...1421.9     36.2     24     42GO:0045025; C:mitochondrial degradosome; IDA:UniProtKB.::GO:0042645; C:mitochondrial nucleoid; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0034458; F:3'-5' RNA helicase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IDA:UniProtKB.::GO:0003677; F:DNA binding; IMP:UniProtKB.::GO:0003678; F:DNA helicase activity; IMP:UniProtKB.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0070827; P:chromatin maintenance; IMP:UniProtKB.::GO:0006310; P:DNA recombination; IMP:UniProtKB.::GO:0000958; P:mitochondrial mRNA catabolic process; IMP:UniProtKB.::GO:0035946; P:mitochondrial mRNA surveillance; IMP:UniProtKB.::GO:0035945; P:mitochondrial ncRNA surveillance; IMP:UniProtKB.::GO:0000965; P:mitochondrial RNA 3'-end processing; IMP:UniProtKB.::GO:0070584; P:mitochondrion morphogenesis; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.::GO:0000962; P:positive regulation of mitochondrial RNA catabolic process; IDA:UniProtKB.
144A4IG62    763   SUV3_DANRE ATP-dependent RNA helicase SUPV3L1...1223     35.4     26     47GO:0045025; C:mitochondrial degradosome; ISS:UniProtKB.::GO:0042645; C:mitochondrial nucleoid; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0034458; F:3'-5' RNA helicase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003678; F:DNA helicase activity; ISS:UniProtKB.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0070827; P:chromatin maintenance; ISS:UniProtKB.::GO:0006310; P:DNA recombination; ISS:UniProtKB.::GO:0000958; P:mitochondrial mRNA catabolic process; ISS:UniProtKB.::GO:0035946; P:mitochondrial mRNA surveillance; ISS:UniProtKB.::GO:0035945; P:mitochondrial ncRNA surveillance; ISS:UniProtKB.::GO:0000965; P:mitochondrial RNA 3'-end processing; ISS:UniProtKB.::GO:0070584; P:mitochondrion morphogenesis; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0000962; P:positive regulation of mitochondrial RNA catabolic process; ISS:UniProtKB.
145Q5R607    1194   DHX30_PONAB Putative ATP-dependent RNA helica...1662     36.2     27     43GO:0042645; C:mitochondrial nucleoid; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
146Q5EBA1    776   SUV3_RAT ATP-dependent RNA helicase SUPV3L1, ...1333     35.4     25     44GO:0045025; C:mitochondrial degradosome; ISS:UniProtKB.::GO:0042645; C:mitochondrial nucleoid; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0034458; F:3'-5' RNA helicase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003678; F:DNA helicase activity; ISS:UniProtKB.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0070827; P:chromatin maintenance; ISS:UniProtKB.::GO:0006310; P:DNA recombination; ISS:UniProtKB.::GO:0000958; P:mitochondrial mRNA catabolic process; ISS:UniProtKB.::GO:0035946; P:mitochondrial mRNA surveillance; ISS:UniProtKB.::GO:0035945; P:mitochondrial ncRNA surveillance; ISS:UniProtKB.::GO:0000965; P:mitochondrial RNA 3'-end processing; ISS:UniProtKB.::GO:0070584; P:mitochondrion morphogenesis; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0000962; P:positive regulation of mitochondrial RNA catabolic process; ISS:UniProtKB.
147Q5ZJT0    794   SUV3_CHICK ATP-dependent RNA helicase SUPV3L1...572.1     36.2     32     58GO:0045025; C:mitochondrial degradosome; ISS:UniProtKB.::GO:0042645; C:mitochondrial nucleoid; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0034458; F:3'-5' RNA helicase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003678; F:DNA helicase activity; ISS:UniProtKB.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0070827; P:chromatin maintenance; ISS:UniProtKB.::GO:0006310; P:DNA recombination; ISS:UniProtKB.::GO:0000958; P:mitochondrial mRNA catabolic process; ISS:UniProtKB.::GO:0035946; P:mitochondrial mRNA surveillance; ISS:UniProtKB.::GO:0035945; P:mitochondrial ncRNA surveillance; ISS:UniProtKB.::GO:0000965; P:mitochondrial RNA 3'-end processing; ISS:UniProtKB.::GO:0070584; P:mitochondrion morphogenesis; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0000962; P:positive regulation of mitochondrial RNA catabolic process; ISS:UniProtKB.
148Q1DCA2    479   GATB_MYXXD Aspartyl/glutamyl-tRNA(Asn/Gln) am...1002.3     35.8     30     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016884; F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor; IEA:InterPro.
GO:0006412; P:translation; IEA:UniProtKB-KW.
149P76257    636   YOAA_ECOLI Probable ATP-dependent helicase yo...722.3     35.8     38     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
150Q80YD1    779   SUV3_MOUSE ATP-dependent RNA helicase SUPV3L1...1333.2     35.4     25     44GO:0045025; C:mitochondrial degradosome; ISS:UniProtKB.::GO:0042645; C:mitochondrial nucleoid; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0034458; F:3'-5' RNA helicase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003678; F:DNA helicase activity; ISS:UniProtKB.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.
GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0070827; P:chromatin maintenance; ISS:UniProtKB.::GO:0006310; P:DNA recombination; ISS:UniProtKB.::GO:0000958; P:mitochondrial mRNA catabolic process; ISS:UniProtKB.::GO:0035946; P:mitochondrial mRNA surveillance; ISS:UniProtKB.::GO:0035945; P:mitochondrial ncRNA surveillance; ISS:UniProtKB.::GO:0000965; P:mitochondrial RNA 3'-end processing; ISS:UniProtKB.::GO:0070584; P:mitochondrion morphogenesis; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0000962; P:positive regulation of mitochondrial RNA catabolic process; ISS:UniProtKB.
151Q6BLU9    580   PRP28_DEBHA Pre-mRNA-splicing ATP-dependent R...1552.5     35.8     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
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