Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL042W
Length:
1398
Number of sequences:
5887
Description:
YJL042W MHP1 SGDID:S000003578, Chr X from 361249-365445, Genome Release 64-1-1, Verified ORF, "Microtubule-associated protein involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P43638    1398   MHP1_YEAST MAP-homologous protein 1 OS=Saccha...13980     2890     100     100GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IDA:SGD.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005200; F:structural constituent of cytoskeleton; IDA:SGD.
GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0007026; P:negative regulation of microtubule depolymerization; IMP:SGD.
2Q03016    1276   GIP3_YEAST GLC7-interacting protein 3 OS=Sacc...7945e-69     259     29     48GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0008157; F:protein phosphatase 1 binding; IDA:SGD.::GO:0008599; F:protein phosphatase type 1 regulator activity; IMP:SGD.
GO:0007059; P:chromosome segregation; IMP:SGD.::GO:0043666; P:regulation of phosphoprotein phosphatase activity; IMP:SGD.
3Q12276    1246   HER1_YEAST HMG2-induced ER-remodeling protein...7383e-64     244     28     46GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007029; P:endoplasmic reticulum organization; IGI:SGD.
4Q64511    1612   TOP2B_MOUSE DNA topoisomerase 2-beta OS=Mus m...1300.3     39.3     28     42GO:0009330; C:DNA topoisomerase complex (ATP-hydrolyzing); IBA:RefGenome.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000795; C:synaptonemal complex; IBA:RefGenome.::GO:0071778; C:WINAC complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IBA:RefGenome.::GO:0042826; F:histone deacetylase binding; IBA:RefGenome.::GO:0005080; F:protein kinase C binding; IBA:RefGenome.
GO:0007409; P:axonogenesis; IMP:MGI.::GO:0006265; P:DNA topological change; IBA:RefGenome.::GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IBA:RefGenome.::GO:0006312; P:mitotic recombination; IBA:RefGenome.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.::GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
5Q6BCB4    1045   SC16B_RABIT Protein transport protein Sec16B ...1470.31     39.3     27     37GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0048208; P:COPII vesicle coating; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
6Q64399    1612   TOP2B_CRILO DNA topoisomerase 2-beta OS=hamst...1300.31     39.3     28     42GO:0005694; C:chromosome; IEA:InterPro.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
7Q9FZ59    1088   PEPR2_ARATH Leucine-rich repeat receptor-like...1630.87     37.7     29     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042277; F:peptide binding; IDA:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0009753; P:response to jasmonic acid stimulus; IEP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR.
8Q8RP17    774   HOPW1_PSEYM Effector protein hopW1-1 OS=Pseud...721     37.4     31     50GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
9Q9HC29    1040   NOD2_HUMAN Nucleotide-binding oligomerization...1513     36.2     23     44GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:HGNC.::GO:0005886; C:plasma membrane; IDA:HGNC.::GO:0031982; C:vesicle; IDA:HGNC.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050700; F:CARD domain binding; IPI:UniProtKB.::GO:0032500; F:muramyl dipeptide binding; IDA:HGNC.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0035419; P:activation of MAPK activity involved in innate immune response; ISS:BHF-UCL.::GO:0002367; P:cytokine production involved in immune response; IMP:UniProtKB.::GO:0016045; P:detection of bacterium; IDA:HGNC.::GO:0032498; P:detection of muramyl dipeptide; IDA:MGI.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:2000110; P:negative regulation of macrophage apoptotic process; ISS:BHF-UCL.::GO:0070431; P:nucleotide-binding oligomerization domain containing 2 signaling pathway; IDA:MGI.::GO:0050871; P:positive regulation of B cell activation; IDA:BHF-UCL.::GO:0002606; P:positive regulation of dendritic cell antigen processing and presentation; ISS:BHF-UCL.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:BHF-UCL.::GO:0046645; P:positive regulation of gamma-delta T cell activation; ISS:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0050718; P:positive regulation of interleukin-1 beta secretion; IDA:HGNC.::GO:0032733; P:positive regulation of interleukin-10 production; ISS:BHF-UCL.::GO:0032740; P:positive regulation of interleukin-17 production; IMP:UniProtKB.::GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; IDA:MGI.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:BHF-UCL.::GO:0045747; P:positive regulation of Notch signaling pathway; ISS:BHF-UCL.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:BHF-UCL.::GO:2000363; P:positive regulation of prostaglandin-E synthase activity; ISS:BHF-UCL.::GO:0060585; P:positive regulation of prostaglandin-endoperoxide synthase activity; ISS:BHF-UCL.::GO:0032760; P:positive regulation of tumor necrosis factor production; IMP:BHF-UCL.::GO:0002830; P:positive regulation of type 2 immune response; IMP:BHF-UCL.::GO:0051259; P:protein oligomerization; TAS:HGNC.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
10Q91W10    462   S39A8_MOUSE Zinc transporter ZIP8 OS=Mus musc...733.2     35.8     33     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031090; C:organelle membrane; ISS:UniProtKB.
GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
GO:0006829; P:zinc ion transport; ISS:UniProtKB.
11Q53B88    1040   NOD2_HYLLA Nucleotide-binding oligomerization...1513.7     35.8     23     44GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0031982; C:vesicle; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050700; F:CARD domain binding; ISS:UniProtKB.::GO:0032500; F:muramyl dipeptide binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0002367; P:cytokine production involved in immune response; ISS:UniProtKB.::GO:0042742; P:defense response to bacterium; ISS:UniProtKB.::GO:0016045; P:detection of bacterium; ISS:UniProtKB.::GO:0032498; P:detection of muramyl dipeptide; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0050718; P:positive regulation of interleukin-1 beta secretion; ISS:UniProtKB.::GO:0032740; P:positive regulation of interleukin-17 production; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
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