Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL041W
Length:
823
Number of sequences:
5887
Description:
YJL041W NSP1 SGDID:S000003577, Chr X from 365784-365784,365903-368373, Genome Release 64-1-1, Verified ORF, "Essential component of the nuclear pore complex, which mediates nuclear import and export, found in both the Nup82 and Nic96 complexes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P14907    823   NSP1_YEAST Nucleoporin NSP1 OS=Saccharomyces ...8230     1579     100     100GO:0055125; C:Nic96 complex; IDA:SGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0055126; C:Nup82 complex; IDA:SGD.
GO:0005543; F:phospholipid binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0097064; P:ncRNA export from nucleus; IMP:SGD.::GO:0016973; P:poly(A)+ mRNA export from nucleus; IGI:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.::GO:0000055; P:ribosomal large subunit export from nucleus; IMP:SGD.::GO:0000056; P:ribosomal small subunit export from nucleus; IMP:SGD.::GO:0006409; P:tRNA export from nucleus; IMP:SGD.
2Q10168    598   NSP1_SCHPO Nucleoporin nsp1 OS=Schizosaccharo...4257.6     33.9     31     40GO:0031965; C:nuclear membrane; IDA:PomBase.::GO:0005643; C:nuclear pore; IDA:PomBase.
GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.
GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0000054; P:ribosomal subunit export from nucleus; ISS:PomBase.
3P37198    522   NUP62_HUMAN Nuclear pore glycoprotein p62 OS=...1882e-26     118     30     54GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005643; C:nuclear pore; IDA:UniProtKB.::GO:0031074; C:nucleocytoplasmic shuttling complex; NAS:UniProtKB.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; NAS:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IDA:UniProtKB.::GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.::GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.::GO:0008219; P:cell death; IMP:UniProtKB.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0009755; P:hormone-mediated signaling pathway; NAS:UniProtKB.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0006913; P:nucleocytoplasmic transport; NAS:GOC.::GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; NAS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0010827; P:regulation of glucose transport; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IDA:UniProtKB.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
4Q63850    526   NUP62_MOUSE Nuclear pore glycoprotein p62 OS=...1826e-24     110     29     52GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005643; C:nuclear pore; ISS:UniProtKB.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051425; F:PTB domain binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.::GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.::GO:0046966; F:thyroid hormone receptor binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.
GO:0007569; P:cell aging; IDA:MGI.::GO:0008219; P:cell death; ISS:UniProtKB.::GO:0016477; P:cell migration; NAS:UniProtKB.::GO:0007166; P:cell surface receptor signaling pathway; ISS:UniProtKB.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:UniProtKB.::GO:0046580; P:negative regulation of Ras protein signal transduction; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB.
5P17955    525   NUP62_RAT Nuclear pore glycoprotein p62 OS=Ra...1821e-23     109     29     52GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005643; C:nuclear pore; ISS:UniProtKB.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.::GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.::GO:0046966; F:thyroid hormone receptor binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.
GO:0008219; P:cell death; ISS:UniProtKB.::GO:0007166; P:cell surface receptor signaling pathway; ISS:UniProtKB.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; ISS:UniProtKB.
6P20676    1076   NUP1_YEAST Nucleoporin NUP1 OS=Saccharomyces ...3770.000000000000002     84.7     31     46GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005198; F:structural molecule activity; TAS:SGD.
GO:0006607; P:NLS-bearing substrate import into nucleus; IMP:SGD.::GO:0016973; P:poly(A)+ mRNA export from nucleus; IMP:SGD.::GO:0000055; P:ribosomal large subunit export from nucleus; IMP:SGD.::GO:0000972; P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; IMP:SGD.
7P32499    720   NUP2_YEAST Nucleoporin NUP2 OS=Saccharomyces ...1970.32     38.1     31     45GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000790; C:nuclear chromatin; IDA:SGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005198; F:structural molecule activity; TAS:SGD.
GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0031990; P:mRNA export from nucleus in response to heat stress; IMP:SGD.::GO:0006609; P:mRNA-binding (hnRNP) protein import into nucleus; TAS:SGD.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:SGD.::GO:0006999; P:nuclear pore organization; TAS:SGD.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; IMP:SGD.::GO:0016973; P:poly(A)+ mRNA export from nucleus; IMP:SGD.::GO:0000973; P:posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery; IMP:SGD.::GO:0006611; P:protein export from nucleus; TAS:SGD.::GO:0006612; P:protein targeting to membrane; IMP:SGD.::GO:0006610; P:ribosomal protein import into nucleus; TAS:SGD.::GO:0006407; P:rRNA export from nucleus; TAS:SGD.::GO:0006408; P:snRNA export from nucleus; TAS:SGD.::GO:0006608; P:snRNP protein import into nucleus; TAS:SGD.::GO:0006409; P:tRNA export from nucleus; TAS:SGD.
8P49791    1468   NU153_RAT Nuclear pore complex protein Nup153...3240.003     45.1     31     43GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008536; F:Ran GTPase binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IDA:RGD.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
9Q9H1M0    184   N62CL_HUMAN Nucleoporin-62 C-terminal-like pr...820.000002     52.8     30     52GO:0005643; C:nuclear pore; IEA:InterPro.
GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
10Q9FKA5    381   Y5957_ARATH Uncharacterized protein At5g39570...2640.0001     48.5     22     44GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
11P49790    1475   NU153_HUMAN Nuclear pore complex protein Nup1...2210.0002     48.5     31     43GO:0005737; C:cytoplasm; IDA:HPA.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005643; C:nuclear pore; TAS:ProtInc.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; TAS:ProtInc.
GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0010827; P:regulation of glucose transport; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
12G5EEH9    1678   NUP98_CAEEL Nuclear pore complex protein Nup9...2590.0007     47     34     45GO:0005643; C:nuclear pore; IEA:InterPro.::GO:0043186; C:P granule; IDA:WormBase.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006997; P:nucleus organization; IMP:WormBase.::GO:0006810; P:transport; IEA:InterPro.
13Q8ILR9    4662   YPF17_PLAF7 Protein PF14_0175 OS=Plasmodium f...1520.033     41.6     28     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
14Q966L9    974   GLH2_CAEEL ATP-dependent RNA helicase glh-2 O...443.1     35     45     52GO:0043186; C:P granule; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0008432; F:JUN kinase binding; IPI:WormBase.::GO:0043621; F:protein self-association; IPI:WormBase.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003724; F:RNA helicase activity; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0009791; P:post-embryonic development; IMP:WormBase.
15Q502M6    298   ANR29_DANRE Ankyrin repeat domain-containing ...1600.33     37.7     27     42
16P52948    1817   NUP98_HUMAN Nuclear pore complex protein Nup9...990.49     37.7     37     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:ProtInc.::GO:0031080; C:Nup107-160 complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0017056; F:structural constituent of nuclear pore; NAS:UniProtKB.::GO:0005215; F:transporter activity; TAS:ProtInc.
GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006260; P:DNA replication; IMP:UniProtKB.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006999; P:nuclear pore organization; NAS:UniProtKB.::GO:0000059; P:protein import into nucleus, docking; NAS:UniProtKB.::GO:0010827; P:regulation of glucose transport; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
17C4Z5N7    939   IF2_EUBE2 Translation initiation factor IF-2 ...700.75     37     29     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
18P40477    1460   NU159_YEAST Nucleoporin NUP159 OS=Saccharomyc...1111     36.6     36     51GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0055126; C:Nup82 complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005198; F:structural molecule activity; TAS:SGD.
GO:0097064; P:ncRNA export from nucleus; IMP:SGD.::GO:0031081; P:nuclear pore distribution; IMP:SGD.::GO:0016973; P:poly(A)+ mRNA export from nucleus; IMP:SGD.::GO:0006611; P:protein export from nucleus; IMP:SGD.::GO:0000055; P:ribosomal large subunit export from nucleus; IMP:SGD.::GO:0000056; P:ribosomal small subunit export from nucleus; IMP:SGD.
19P17855    715   STC2_STAAU Staphylocoagulase OS=Staphylococcu...1645.8     34.3     25     46
GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.
20P07767    658   STC1_STAAU Staphylocoagulase OS=Staphylococcu...1641.7     35.8     25     48
GO:0016504; F:peptidase activator activity; IEA:UniProtKB-KW.
21P11533    3660   DMD_CHICK Dystrophin OS=Gallus gallus (Chicke...2122.8     35.4     21     45GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
22Q6BZG0    967   SPT5_DEBHA Transcription elongation factor SP...892.9     35     35     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0032784; P:regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23D3ZHV2    5430   MACF1_RAT Microtubule-actin cross-linking fac...1485.7     34.3     26     47GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005874; C:microtubule; ISS:UniProtKB.::GO:0032587; C:ruffle membrane; ISS:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0043001; P:Golgi to plasma membrane protein transport; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0010632; P:regulation of epithelial cell migration; ISS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.::GO:0042060; P:wound healing; ISS:UniProtKB.
24Q8WN22    4144   PRKDC_CANFA DNA-dependent protein kinase cata...1396.2     34.3     23     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
25O67517    249   Y1575_AQUAE Probable transcriptional regulato...606.7     33.5     35     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26Q21338    1208   SPT5H_CAEEL Transcription elongation factor S...1077.2     33.9     31     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27P41546    238   HAC1_YEAST Transcriptional activator HAC1 OS=...717.8     33.1     28     48GO:0005634; C:nucleus; IDA:SGD.
GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:SGD.
GO:0010674; P:negative regulation of transcription from RNA polymerase II promoter during meiosis; IMP:SGD.::GO:0006990; P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response; IMP:SGD.
28P49793    1816   NUP98_RAT Nuclear pore complex protein Nup98-...998.4     33.9     35     46GO:0005654; C:nucleoplasm; IDA:RGD.::GO:0031080; C:Nup107-160 complex; ISS:UniProtKB.
GO:0042277; F:peptide binding; IDA:RGD.::GO:0005515; F:protein binding; IPI:RGD.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000059; P:protein import into nucleus, docking; IMP:RGD.
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