Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL034W
Length:
682
Number of sequences:
5887
Description:
YJL034W KAR2 SGDID:S000003571, Chr X from 381327-383375, Genome Release 64-1-1, Verified ORF, "ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P16474    682   GRP78_YEAST 78 kDa glucose-regulated protein ...6820     1374     100     100GO:0034099; C:luminal surveillance complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0051082; F:unfolded protein binding; IMP:SGD.
GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0000742; P:karyogamy involved in conjugation with cellular fusion; IGI:SGD.::GO:0031204; P:posttranslational protein targeting to membrane, translocation; IDA:SGD.::GO:0006986; P:response to unfolded protein; IMP:SGD.::GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IMP:SGD.
2Q6FW50    667   GRP78_CANGA 78 kDa glucose-regulated protein ...6560     1182     90     95GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
3Q75C78    674   GRP78_ASHGO 78 kDa glucose-regulated protein ...6830     1104     80     91GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
4P22010    679   GRP78_KLULA 78 kDa glucose-regulated protein ...6530     1048     79     88GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
5Q6BZH1    683   GRP78_DEBHA 78 kDa glucose-regulated protein ...6710     997     75     85GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
6Q99170    670   GRP78_YARLI 78 kDa glucose-regulated protein ...6830     994     73     83GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006986; P:response to unfolded protein; ISS:UniProtKB.
7Q9HG01    665   GRP78_PICAN 78 kDa glucose-regulated protein ...6140     974     79     89GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006986; P:response to unfolded protein; ISS:UniProtKB.
8P78695    661   GRP78_NEUCR 78 kDa glucose-regulated protein ...6530     973     75     85GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
9P83616    672   GRP78_ASPNG 78 kDa glucose-regulated protein ...6770     959     72     83GO:0005788; C:endoplasmic reticulum lumen; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006986; P:response to unfolded protein; IDA:UniProtKB.::GO:0032940; P:secretion by cell; NAS:UniProtKB.
10P83617    672   GRP78_ASPKA 78 kDa glucose-regulated protein ...6770     959     72     83GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006986; P:response to unfolded protein; ISS:UniProtKB.
11P59769    672   GRP78_ASPAW 78 kDa glucose-regulated protein ...6770     959     72     83GO:0005788; C:endoplasmic reticulum lumen; NAS:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.
GO:0006986; P:response to unfolded protein; IDA:UniProtKB.
12P36604    663   GRP78_SCHPO 78 kDa glucose-regulated protein ...6430     897     70     84GO:0005788; C:endoplasmic reticulum lumen; IDA:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0031965; C:nuclear membrane; IDA:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0051082; F:unfolded protein binding; ISS:PomBase.
GO:0051084; P:'de novo' posttranslational protein folding; IDA:PomBase.::GO:0034620; P:cellular response to unfolded protein; ISS:PomBase.::GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase.
13P07823    654   GRP78_MESAU 78 kDa glucose-regulated protein ...6340     860     68     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
14Q90593    652   GRP78_CHICK 78 kDa glucose-regulated protein ...6160     860     69     83GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
15Q0VCX2    655   GRP78_BOVIN 78 kDa glucose-regulated protein ...6340     860     68     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
16P20029    655   GRP78_MOUSE 78 kDa glucose-regulated protein ...6340     860     68     81GO:0009986; C:cell surface; IDA:MGI.::GO:0005788; C:endoplasmic reticulum lumen; IDA:BHF-UCL.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051787; F:misfolded protein binding; IDA:BHF-UCL.::GO:0043022; F:ribosome binding; IDA:MGI.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; IMP:BHF-UCL.::GO:0021680; P:cerebellar Purkinje cell layer development; IMP:BHF-UCL.::GO:0021589; P:cerebellum structural organization; IMP:BHF-UCL.::GO:0006983; P:ER overload response; IDA:MGI.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IGI:MGI.::GO:0040019; P:positive regulation of embryonic development; TAS:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IMP:BHF-UCL.::GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:BHF-UCL.
17P06761    654   GRP78_RAT 78 kDa glucose-regulated protein OS...6340     859     68     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IPI:RGD.
18P11021    654   GRP78_HUMAN 78 kDa glucose-regulated protein ...6340     858     68     81GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0034663; C:endoplasmic reticulum chaperone complex; IDA:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; TAS:UniProtKB.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; TAS:UniProtKB.::GO:0051087; F:chaperone binding; TAS:BHF-UCL.::GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.::GO:0051787; F:misfolded protein binding; IDA:UniProtKB.::GO:0030674; F:protein binding, bridging; NAS:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0051082; F:unfolded protein binding; TAS:UniProtKB.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; TAS:BHF-UCL.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.::GO:0060904; P:regulation of protein folding in endoplasmic reticulum; TAS:BHF-UCL.
19Q3S4T7    654   GRP78_SPETR 78 kDa glucose-regulated protein ...6340     856     68     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
20Q5R4P0    654   GRP78_PONAB 78 kDa glucose-regulated protein ...6340     855     68     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
21Q91883    658   GRP78_XENLA 78 kDa glucose-regulated protein ...6450     853     66     80GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
22Q03685    668   BIP5_TOBAC Luminal-binding protein 5 OS=Nicot...6660     851     64     78GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
23P19208    661   HSP7C_CAEBR Heat shock 70 kDa protein C OS=Ca...6310     850     67     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
24Q03684    667   BIP4_TOBAC Luminal-binding protein 4 OS=Nicot...6310     844     66     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
25P27420    661   HSP7C_CAEEL Heat shock 70 kDa protein C OS=Ca...6280     843     67     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IEP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0009306; P:protein secretion; ISS:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
26Q42434    668   BIP_SPIOL Luminal-binding protein OS=Spinacia...6520     842     64     79GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
27P49118    666   BIP_SOLLC Luminal-binding protein OS=Solanum ...6790     836     62     76GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
28Q16956    667   GRP78_APLCA 78 kDa glucose-regulated protein ...6400     833     66     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
29Q39043    668   HSP7L_ARATH Heat shock 70 kDa protein 12 OS=A...6210     833     66     81GO:0005618; C:cell wall; IDA:TAIR.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0010197; P:polar nucleus fusion; IGI:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.
30Q24895    649   GRP78_ECHMU 78 kDa glucose-regulated protein ...6140     829     66     82GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
31Q24798    651   GRP78_ECHGR 78 kDa glucose-regulated protein ...6220     828     65     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
records
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