Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL034W
Length:
682
Number of sequences:
5887
Description:
YJL034W KAR2 SGDID:S000003571, Chr X from 381327-383375, Genome Release 64-1-1, Verified ORF, "ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P10591    642   HSP71_YEAST Heat shock protein SSA1 OS=Saccha...6040     793     65     80GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0009277; C:fungal-type cell wall; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.::GO:0005844; C:polysome; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0051082; F:unfolded protein binding; IDA:SGD.
GO:0002181; P:cytoplasmic translation; IMP:SGD.::GO:0000060; P:protein import into nucleus, translocation; IDA:SGD.::GO:0042026; P:protein refolding; IDA:SGD.::GO:0006626; P:protein targeting to mitochondrion; IMP:SGD.::GO:0006950; P:response to stress; IMP:SGD.::GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IDA:SGD.
62Q10265    644   HSP71_SCHPO Probable heat shock protein ssa1 ...6060     793     63     81GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0051082; F:unfolded protein binding; ISS:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0002181; P:cytoplasmic translation; NAS:PomBase.::GO:0042026; P:protein refolding; ISS:PomBase.
63Q90473    649   HSP7C_DANRE Heat shock cognate 71 kDa protein...6120     793     63     79
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
64P54652    639   HSP72_HUMAN Heat shock-related 70 kDa protein...6110     792     63     80GO:0036128; C:CatSper complex; ISS:UniProtKB.::GO:0009986; C:cell surface; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; TAS:ProtInc.
GO:0006986; P:response to unfolded protein; TAS:ProtInc.::GO:0007286; P:spermatid development; TAS:ProtInc.
65P14659    633   HSP72_RAT Heat shock-related 70 kDa protein 2...6110     791     63     80GO:0036128; C:CatSper complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
66P17156    633   HSP72_MOUSE Heat shock-related 70 kDa protein...6110     791     63     80GO:0036128; C:CatSper complex; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:MGI.::GO:0001673; C:male germ cell nucleus; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000795; C:synaptonemal complex; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051861; F:glycolipid binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007141; P:male meiosis I; IMP:MGI.::GO:0031662; P:positive regulation of cyclin-dependent protein kinase activity involved in G2/M; IMP:MGI.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:MGI.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0007286; P:spermatid development; IMP:MGI.::GO:0070194; P:synaptonemal complex disassembly; IMP:MGI.
67Q4R888    641   HS71L_MACFA Heat shock 70 kDa protein 1-like ...6180     791     62     79
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
68Q7YQC6    641   HSP71_CANFA Heat shock 70 kDa protein 1 OS=Ca...6060     790     63     80GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
69P09189    651   HSP7C_PETHY Heat shock cognate 70 kDa protein...6240     791     62     78
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
70Q61696    641   HS71A_MOUSE Heat shock 70 kDa protein 1A OS=M...6080     790     63     80GO:0005739; C:mitochondrion; ISS:MGI.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006281; P:DNA repair; IMP:MGI.::GO:0006402; P:mRNA catabolic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0009408; P:response to heat; IDA:MGI.::GO:0006986; P:response to unfolded protein; ISS:UniProtKB.::GO:0000723; P:telomere maintenance; IMP:MGI.
71P17879    642   HS71B_MOUSE Heat shock 70 kDa protein 1B OS=M...6080     790     63     80GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0006916; P:anti-apoptosis; IDA:MGI.::GO:0006281; P:DNA repair; IMP:MGI.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.::GO:0009408; P:response to heat; IDA:MGI.::GO:0000723; P:telomere maintenance; IMP:MGI.
72P08418    637   HSP70_SCHMA Heat shock 70 kDa protein homolog...6120     790     62     79
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
73P10592    639   HSP72_YEAST Heat shock protein SSA2 OS=Saccha...6090     790     64     80GO:0005829; C:cytosol; IDA:SGD.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0009277; C:fungal-type cell wall; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.::GO:0005844; C:polysome; IDA:SGD.
GO:0005524; F:ATP binding; IDA:SGD.::GO:0016887; F:ATPase activity; ISS:SGD.::GO:0051082; F:unfolded protein binding; ISS:SGD.
GO:0006457; P:protein folding; IDA:SGD.::GO:0006950; P:response to stress; IMP:SGD.::GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IMP:SGD.
74Q9TUG3    636   HSP72_CAPHI Heat shock-related 70 kDa protein...6110     790     63     80GO:0036128; C:CatSper complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
75Q07439    641   HSP71_RAT Heat shock 70 kDa protein 1A/1B OS=...6080     790     63     80GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051059; F:NF-kappaB binding; IPI:RGD.::GO:0002020; F:protease binding; IPI:RGD.
GO:0006952; P:defense response; IDA:RGD.::GO:0006402; P:mRNA catabolic process; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:RGD.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:RGD.::GO:0045906; P:negative regulation of vasoconstriction; IMP:RGD.::GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IDA:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0006986; P:response to unfolded protein; ISS:UniProtKB.
76Q6S4N2    641   HS71B_PIG Heat shock 70 kDa protein 1B OS=Sus...6060     790     63     80GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; ISS:AgBase.::GO:0006281; P:DNA repair; ISS:AgBase.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:AgBase.::GO:0009408; P:response to heat; ISS:AgBase.::GO:0000723; P:telomere maintenance; ISS:AgBase.
77Q9I8F9    639   HSP71_ORYLA Heat shock 70 kDa protein 1 OS=Or...6150     789     62     79
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
78P34931    641   HS71L_HUMAN Heat shock 70 kDa protein 1-like ...6190     789     62     79
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006986; P:response to unfolded protein; TAS:ProtInc.
79Q8H1B3    675   HSP7M_ARATH Heat shock 70 kDa protein 13 OS=A...6600     790     62     77GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0009860; P:pollen tube growth; IEP:TAIR.
80P34933    636   HSP72_BOVIN Heat shock-related 70 kDa protein...6110     788     63     80GO:0036128; C:CatSper complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
81P36415    640   HS7C1_DICDI Heat shock cognate 70 kDa protein...6070     786     63     79GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:dictyBase.
82P09435    649   HSP73_YEAST Heat shock protein SSA3 OS=Saccha...6060     786     63     80GO:0005829; C:cytosol; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IGI:SGD.::GO:0051082; F:unfolded protein binding; ISS:SGD.
GO:0006950; P:response to stress; IMP:SGD.::GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IMP:SGD.
83Q9U639    652   HSP7D_MANSE Heat shock 70 kDa protein cognate...6060     786     62     80GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
84Q9LHA8    650   HSP7D_ARATH Heat shock 70 kDa protein 4 OS=Ar...6280     786     62     79GO:0005618; C:cell wall; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IDA:TAIR.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
GO:0016567; P:protein ubiquitination; IMP:UniProtKB.::GO:0009617; P:response to bacterium; IEP:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009408; P:response to heat; IEP:UniProtKB.::GO:0009644; P:response to high light intensity; IEP:TAIR.::GO:0042542; P:response to hydrogen peroxide; IEP:TAIR.::GO:0009615; P:response to virus; IEP:TAIR.
85P08106    634   HSP70_CHICK Heat shock 70 kDa protein OS=Gall...6110     783     63     79GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:AgBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009408; P:response to heat; IDA:AgBase.
86P47773    649   HSP7C_ICTPU Heat shock cognate 71 kDa protein...6090     783     63     79
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
87P09446    640   HSP7A_CAEEL Heat shock 70 kDa protein A OS=Ca...6070     783     63     79GO:0005829; C:cytosol; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:WormBase.::GO:0005515; F:protein binding; IPI:WormBase.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0009408; P:response to heat; IDA:WormBase.::GO:0042147; P:retrograde transport, endosome to Golgi; IMP:WormBase.
88Q96W30    654   HSP72_PARBA Heat shock 70 kDa protein 2 OS=Pa...6070     782     62     79
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
89Q01233    646   HSP70_NEUCR Heat shock 70 kDa protein OS=1257...6070     781     62     79
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
90P34930    641   HS71A_PIG Heat shock 70 kDa protein 1A OS=Sus...6060     780     63     80GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
91P41753    652   HSP70_ACHKL Heat shock 70 kDa protein OS=Achl...6100     779     62     78
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
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