Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL034W
Length:
682
Number of sequences:
5887
Description:
YJL034W KAR2 SGDID:S000003571, Chr X from 381327-383375, Genome Release 64-1-1, Verified ORF, "ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q24798    651   GRP78_ECHGR 78 kDa glucose-regulated protein ...6220     828     65     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
32P29844    656   HSP7C_DROME Heat shock 70 kDa protein cognate...6290     827     67     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:FlyBase.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0051298; P:centrosome duplication; IMP:FlyBase.::GO:0016246; P:RNA interference; IMP:FlyBase.::GO:0030431; P:sleep; TAS:FlyBase.
33Q9LKR3    669   HSP7K_ARATH Heat shock 70 kDa protein 11 OS=A...6440     826     64     78GO:0005618; C:cell wall; IDA:TAIR.::GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0030433; P:ER-associated protein catabolic process; IMP:TAIR.::GO:0010197; P:polar nucleus fusion; IGI:TAIR.
34P20163    657   HSP7D_CAEEL Heat shock 70 kDa protein D OS=Ca...6310     823     65     79GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IEP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
35P24067    663   BIP2_MAIZE Luminal-binding protein 2 OS=Zea m...6170     814     67     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
36O24581    663   BIP3_MAIZE Luminal-binding protein 3 OS=Zea m...6170     813     66     81GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
37Q5NVM9    646   HSP7C_PONAB Heat shock cognate 71 kDa protein...6090     811     65     80GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
38P63018    646   HSP7C_RAT Heat shock cognate 71 kDa protein O...6090     811     65     80GO:0070062; C:extracellular vesicular exosome; IDA:RGD.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0008021; C:synaptic vesicle; IDA:RGD.
GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0042623; F:ATPase activity, coupled; IDA:RGD.::GO:0005102; F:receptor binding; IPI:RGD.::GO:0051082; F:unfolded protein binding; IMP:RGD.
GO:0051085; P:chaperone mediated protein folding requiring cofactor; IDA:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
39P63017    646   HSP7C_MOUSE Heat shock cognate 71 kDa protein...6090     811     65     80GO:0005829; C:cytosol; IDA:MGI.::GO:0070062; C:extracellular vesicular exosome; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; IDA:MGI.::GO:0051082; F:unfolded protein binding; IPI:MGI.
GO:0051085; P:chaperone mediated protein folding requiring cofactor; IGI:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; IDA:MGI.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
40Q71U34    646   HSP7C_SAGOE Heat shock cognate 71 kDa protein...6090     810     65     80GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
41P11142    646   HSP7C_HUMAN Heat shock cognate 71 kDa protein...6090     810     65     80GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0061202; C:clathrin sculpted gamma-aminobutyric acid transport vesicle membrane; TAS:Reactome.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0030529; C:ribonucleoprotein complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042623; F:ATPase activity, coupled; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0007269; P:neurotransmitter secretion; TAS:Reactome.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.::GO:0006457; P:protein folding; NAS:UniProtKB.::GO:0006986; P:response to unfolded protein; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
42A2Q0Z1    646   HSP7C_HORSE Heat shock cognate 71 kDa protein...6090     810     65     80GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
43P19120    650   HSP7C_BOVIN Heat shock cognate 71 kDa protein...6090     810     65     80GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
44O73885    646   HSP7C_CHICK Heat shock cognate 71 kDa protein...6090     805     64     80GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0016044; P:cellular membrane organization; ISS:UniProtKB.::GO:0006892; P:post-Golgi vesicle-mediated transport; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
45P19378    646   HSP7C_CRIGR Heat shock cognate 71 kDa protein...6090     804     64     80GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46O59855    647   HSP72_SCHPO Probable heat shock protein ssa2 ...6060     803     64     81GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0051082; F:unfolded protein binding; ISS:PomBase.
GO:0034605; P:cellular response to heat; IEP:PomBase.::GO:0061077; P:chaperone-mediated protein folding; NAS:PomBase.::GO:0042026; P:protein refolding; ISS:PomBase.
47Q01877    648   HSP71_PUCGR Heat shock protein HSS1 OS=Puccin...6060     800     65     79GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
48P55063    641   HS71L_RAT Heat shock 70 kDa protein 1-like OS...6220     797     63     79GO:0005759; C:mitochondrial matrix; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
49P16627    641   HS71L_MOUSE Heat shock 70 kDa protein 1-like ...6120     797     63     80
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
50Q91233    644   HSP70_ONCTS Heat shock 70 kDa protein OS=Onco...6090     797     62     80
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
51Q8T869    658   BIP2_DICDI Luminal-binding protein 2 OS=Dicty...6410     796     63     78GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
52Q27965    641   HS71B_BOVIN Heat shock 70 kDa protein 1B OS=B...6080     795     63     80
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; ISS:AgBase.::GO:0006281; P:DNA repair; ISS:AgBase.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:AgBase.::GO:0009408; P:response to heat; ISS:AgBase.::GO:0000723; P:telomere maintenance; ISS:AgBase.
53P22202    642   HSP74_YEAST Heat shock protein SSA4 OS=Saccha...6060     795     65     80GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:SGD.::GO:0051082; F:unfolded protein binding; ISS:SGD.
GO:0006950; P:response to stress; IDA:SGD.::GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IMP:SGD.
54P0CB32    641   HS71L_BOVIN Heat shock 70 kDa protein 1-like ...6180     795     63     80
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
55A5A8V7    641   HS71L_PIG Heat shock 70 kDa protein 1-like OS...6180     795     63     80
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
56P08108    651   HSP70_ONCMY Heat shock cognate 70 kDa protein...6090     795     64     79
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
57Q4U0F3    641   HS71B_BOSMU Heat shock 70 kDa protein 1B OS=B...6080     794     63     80
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
58Q27975    641   HS71A_BOVIN Heat shock 70 kDa protein 1A OS=B...6060     794     63     80
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
59Q5R7D3    641   HSP71_PONAB Heat shock 70 kDa protein 1 OS=Po...6060     793     63     80GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
60P08107    641   HSP71_HUMAN Heat shock 70 kDa protein 1A/1B O...6060     793     63     80GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; TAS:UniProtKB.::GO:0016234; C:inclusion body; IDA:BHF-UCL.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0030529; C:ribonucleoprotein complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0044183; F:protein binding involved in protein folding; IDA:BHF-UCL.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0051082; F:unfolded protein binding; TAS:UniProtKB.
GO:0006916; P:anti-apoptosis; TAS:UniProtKB.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0006402; P:mRNA catabolic process; IDA:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0090084; P:negative regulation of inclusion body assembly; IDA:BHF-UCL.::GO:0042026; P:protein refolding; IDA:BHF-UCL.::GO:0006986; P:response to unfolded protein; IDA:UniProtKB.
61P10591    642   HSP71_YEAST Heat shock protein SSA1 OS=Saccha...6040     793     65     80GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0009277; C:fungal-type cell wall; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.::GO:0005844; C:polysome; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0051082; F:unfolded protein binding; IDA:SGD.
GO:0002181; P:cytoplasmic translation; IMP:SGD.::GO:0000060; P:protein import into nucleus, translocation; IDA:SGD.::GO:0042026; P:protein refolding; IDA:SGD.::GO:0006626; P:protein targeting to mitochondrion; IMP:SGD.::GO:0006950; P:response to stress; IMP:SGD.::GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IDA:SGD.
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