Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL030W
Length:
196
Number of sequences:
5887
Description:
YJL030W MAD2 SGDID:S000003567, Chr X from 387657-388247, Genome Release 64-1-1, Verified ORF, "Component of the spindle-assembly checkpoint complex; delays the onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p; regulates APC/C activity during prometaphase and metaphase of meiosis I"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40958    196   MAD2_YEAST Mitotic spindle checkpoint compone...1961e-143     405     100     100GO:0033597; C:mitotic checkpoint complex; IDA:SGD.::GO:0005643; C:nuclear pore; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051312; P:chromosome decondensation; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IGI:SGD.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IGI:SGD.
2O14417    203   MAD2_SCHPO Mitotic spindle checkpoint compone...1941e-61     197     49     70GO:0000778; C:condensed nuclear chromosome kinetochore; TAS:PomBase.::GO:0033597; C:mitotic checkpoint complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:PomBase.
3Q556Y9    203   MD2L1_DICDI Mitotic spindle assembly checkpoi...1952e-50     167     47     63GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:dictyBase.
4Q9Z1B5    205   MD2L1_MOUSE Mitotic spindle assembly checkpoi...1941e-47     160     43     62GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0000922; C:spindle pole; IDA:MGI.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:MGI.::GO:0000070; P:mitotic sister chromatid segregation; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0090267; P:positive regulation of mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.
5Q13257    205   MD2L1_HUMAN Mitotic spindle assembly checkpoi...1974e-47     159     43     62GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; IDA:UniProtKB.::GO:0090267; P:positive regulation of mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.
6Q9LU93    209   MAD2_ARATH Mitotic spindle checkpoint protein...1992e-44     152     42     59GO:0010369; C:chromocenter; IDA:TAIR.::GO:0000776; C:kinetochore; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:TAIR.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IDA:TAIR.
7Q9XFH3    208   MAD2_MAIZE Mitotic spindle checkpoint protein...1963e-43     149     42     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
8D3Z8D9    211   MD2L2_RAT Mitotic spindle assembly checkpoint...1830.0000000009     58.9     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB.
GO:0008432; F:JUN kinase binding; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q9D752    211   MD2L2_MOUSE Mitotic spindle assembly checkpoi...1830.0000000009     58.9     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB.
GO:0008432; F:JUN kinase binding; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q2KIP7    211   MD2L2_BOVIN Mitotic spindle assembly checkpoi...1830.000000004     57     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB.
GO:0008432; F:JUN kinase binding; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q568H3    211   MD2L2_DANRE Mitotic spindle assembly checkpoi...1930.00000002     55.1     25     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q4KWZ6    211   MD2L2_CHICK Mitotic spindle assembly checkpoi...1830.00000009     53.5     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB.
GO:0017125; F:deoxycytidyl transferase activity; ISS:AgBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.::GO:0042276; P:error-prone translesion synthesis; ISS:AgBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; IMP:UniProtKB.::GO:0009411; P:response to UV; ISS:AgBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13Q9UI95    211   MD2L2_HUMAN Mitotic spindle assembly checkpoi...1830.0000003     52     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005819; C:spindle; IDA:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; IDA:UniProtKB.
GO:0008432; F:JUN kinase binding; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; IDA:UniProtKB.::GO:0006302; P:double-strand break repair; IGI:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:ProtInc.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; IDA:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0001558; P:regulation of cell growth; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14Q0E7J8    213   REV7_SCHPO DNA polymerase zeta processivity s...1550.0000008     50.8     26     46GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
15Q8QFR4    211   MD2L2_XENLA Mitotic spindle assembly checkpoi...1820.000003     49.3     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB.
GO:0042802; F:identical protein binding; IDA:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; NAS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0009794; P:regulation of mitotic cell cycle, embryonic; IMP:UniProtKB.::GO:0043393; P:regulation of protein binding; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16Q28H85    211   MD2L2_XENTR Mitotic spindle assembly checkpoi...1820.000004     48.9     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17Q54S00    332   MD2L2_DICDI Mitotic spindle assembly checkpoi...880.001     42.4     30     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
18P38927    245   REV7_YEAST DNA polymerase zeta processivity s...1411.1     33.1     26     47GO:0005739; C:mitochondrion; IDA:SGD.::GO:0016035; C:zeta DNA polymerase complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0070987; P:error-free translesion synthesis; IDA:SGD.::GO:0042276; P:error-prone translesion synthesis; IDA:SGD.
19C3PNN8    248   Y648_RICAE UPF0246 protein RAF_ORF0648 OS=Ric...1023.3     31.6     25     46
20Q0AUE7    359   Y2368_SYNWW Putative ATP:guanido phosphotrans...885.1     31.2     30     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0016775; F:phosphotransferase activity, nitrogenous group as acceptor; IEA:InterPro.
21C4K0C5    248   Y055_RICPU UPF0246 protein RPR_00055 OS=Ricke...1025.4     31.2     25     46
22B0BXU8    248   Y836_RICRO UPF0246 protein RrIowa_0836 OS=Ric...1025.8     30.8     25     46
23O68452    248   Y3985_RICRS UPF0246 protein A1G_03985 OS=Rick...1025.8     30.8     25     46
records
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