Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL026W
Length:
399
Number of sequences:
5887
Description:
YJL026W RNR2 SGDID:S000003563, Chr X from 392404-393603, Genome Release 64-1-1, Verified ORF, "Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P09938    399   RIR2_YEAST Ribonucleoside-diphosphate reducta...3990     820     100     100GO:0005634; C:nucleus; IDA:SGD.::GO:0005971; C:ribonucleoside-diphosphate reductase complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IDA:SGD.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; IDA:SGD.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
2Q9C167    410   RIR2_NEUCR Ribonucleoside-diphosphate reducta...4080     527     63     76
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
3P36603    391   RIR2_SCHPO Ribonucleoside-diphosphate reducta...3322e-176     504     72     85GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005971; C:ribonucleoside-diphosphate reductase complex; TAS:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009216; P:purine deoxyribonucleoside triphosphate biosynthetic process; IC:PomBase.::GO:0042278; P:purine nucleoside metabolic process; IC:PomBase.::GO:0009212; P:pyrimidine deoxyribonucleoside triphosphate biosynthetic process; IC:PomBase.::GO:0006213; P:pyrimidine nucleoside metabolic process; IC:PomBase.::GO:0090329; P:regulation of DNA-dependent DNA replication; TAS:PomBase.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IC:PomBase.
4P79733    386   RIR2_DANRE Ribonucleoside-diphosphate reducta...3263e-167     481     70     82GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
5P11157    390   RIR2_MOUSE Ribonucleoside-diphosphate reducta...3929e-165     474     60     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IDA:UniProtKB.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; IDA:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0051290; P:protein heterotetramerization; IPI:UniProtKB.
6P31350    389   RIR2_HUMAN Ribonucleoside-diphosphate reducta...3264e-164     473     69     81GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; NAS:UniProtKB.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.
7Q4KLN6    390   RIR2_RAT Ribonucleoside-diphosphate reductase...3265e-164     473     69     82GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0000278; P:mitotic cell cycle; IEP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0006206; P:pyrimidine base metabolic process; IEP:RGD.
8Q4R7Q7    389   RIR2_MACFA Ribonucleoside-diphosphate reducta...3268e-164     472     68     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
9Q60561    386   RIR2_MESAU Ribonucleoside-diphosphate reducta...3871e-161     466     60     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
10Q5R9G0    351   RIR2B_PONAB Ribonucleoside-diphosphate reduct...3255e-161     464     67     82GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
11Q7LG56    351   RIR2B_HUMAN Ribonucleoside-diphosphate reduct...3256e-161     463     67     82GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
12Q4R741    351   RIR2B_MACFA Ribonucleoside-diphosphate reduct...3257e-161     463     66     82GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
13P07201    384   RIR2_SPISO Ribonucleoside-diphosphate reducta...3822e-160     463     59     74
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
14Q6PEE3    351   RIR2B_MOUSE Ribonucleoside-diphosphate reduct...3258e-160     461     66     82GO:0005739; C:mitochondrion; IC:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IDA:MGI.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009200; P:deoxyribonucleoside triphosphate metabolic process; IMP:MGI.::GO:0009263; P:deoxyribonucleotide biosynthetic process; IDA:MGI.::GO:0006281; P:DNA repair; IMP:MGI.::GO:0001822; P:kidney development; IMP:MGI.::GO:0006264; P:mitochondrial DNA replication; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0003014; P:renal system process; IMP:MGI.::GO:0006979; P:response to oxidative stress; IMP:MGI.
15P48592    393   RIR2_DROME Ribonucleoside-diphosphate reducta...3242e-154     448     65     79GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:FlyBase.::GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
16O57175    319   RIR2_VACCA Ribonucleoside-diphosphate reducta...3242e-153     443     65     78
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
17P11158    319   RIR2_VACCW Ribonucleoside-diphosphate reducta...3241e-152     441     65     78
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
18P20493    319   RIR2_VACCC Ribonucleoside-diphosphate reducta...3243e-152     440     65     78
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
19P29883    319   RIR2_VACCP Ribonucleoside-diphosphate reducta...3245e-152     439     65     78
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
20P33799    319   RIR2_VAR67 Ribonucleoside-diphosphate reducta...3242e-150     436     64     78
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
21Q6Y657    333   RIR2B_ARATH Putative ribonucleoside-diphospha...3293e-146     425     63     76GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
22Q9DHU2    325   RIR2_YLDV Ribonucleoside-diphosphate reductas...3249e-146     424     62     77
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
23Q9LSD0    332   RIR2C_ARATH Ribonucleoside-diphosphate reduct...3281e-144     421     64     76GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006281; P:DNA repair; TAS:TAIR.::GO:0006260; P:DNA replication; IMP:TAIR.::GO:0007275; P:multicellular organismal development; IMP:TAIR.::GO:0012501; P:programmed cell death; IMP:TAIR.::GO:0051726; P:regulation of cell cycle; IMP:TAIR.
24O15910    337   RIR2_TRYBB Ribonucleoside-diphosphate reducta...3411e-144     421     61     76
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
25P42170    381   RIR2_CAEEL Ribonucleoside-diphosphate reducta...3225e-144     421     62     78
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0016477; P:cell migration; IMP:WormBase.::GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0030728; P:ovulation; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
26P42521    338   RIR2_DICDI Ribonucleoside-diphosphate reducta...3061e-143     419     65     80GO:0005634; C:nucleus; ISS:dictyBase.::GO:0005971; C:ribonucleoside-diphosphate reductase complex; ISS:dictyBase.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; ISS:dictyBase.::GO:0042493; P:response to drug; ISS:dictyBase.
27Q8SRR2    325   RIR2_ENCCU Ribonucleoside-diphosphate reducta...3093e-143     417     65     80
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
28O46310    345   RIR2_LEIAM Ribonucleoside-diphosphate reducta...3271e-142     417     61     78
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
29P50651    341   RIR2A_ARATH Ribonucleoside-diphosphate reduct...3329e-142     414     61     75GO:0005829; C:cytosol; IDA:TAIR.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IDA:TAIR.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006281; P:DNA repair; TAS:TAIR.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IMP:TAIR.::GO:0051726; P:regulation of cell cycle; IMP:TAIR.::GO:0009259; P:ribonucleotide metabolic process; TAS:TAIR.
30P49730    329   RIR2_TOBAC Ribonucleoside-diphosphate reducta...3261e-138     406     62     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
31P49723    345   RIR4_YEAST Ribonucleoside-diphosphate reducta...3479e-136     399     54     74GO:0005634; C:nucleus; IDA:SGD.::GO:0005971; C:ribonucleoside-diphosphate reductase complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IMP:SGD.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
GO:0051188; P:cofactor biosynthetic process; IMP:SGD.::GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; IDA:SGD.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
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