rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P09938 | 399 | RIR2_YEAST Ribonucleoside-diphosphate reducta... | 399 | 0 | 820 | 100 | 100 | GO:0005634; C:nucleus; IDA:SGD.::GO:0005971; C:ribonucleoside-diphosphate reductase complex; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IDA:SGD.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; IDA:SGD.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 2 | Q9C167 | 410 | RIR2_NEUCR Ribonucleoside-diphosphate reducta... | 408 | 0 | 527 | 63 | 76 | | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 3 | P36603 | 391 | RIR2_SCHPO Ribonucleoside-diphosphate reducta... | 332 | 2e-176 | 504 | 72 | 85 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005971; C:ribonucleoside-diphosphate reductase complex; TAS:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009216; P:purine deoxyribonucleoside triphosphate biosynthetic process; IC:PomBase.::GO:0042278; P:purine nucleoside metabolic process; IC:PomBase.::GO:0009212; P:pyrimidine deoxyribonucleoside triphosphate biosynthetic process; IC:PomBase.::GO:0006213; P:pyrimidine nucleoside metabolic process; IC:PomBase.::GO:0090329; P:regulation of DNA-dependent DNA replication; TAS:PomBase.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IC:PomBase. | 4 | P79733 | 386 | RIR2_DANRE Ribonucleoside-diphosphate reducta... | 326 | 3e-167 | 481 | 70 | 82 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 5 | P11157 | 390 | RIR2_MOUSE Ribonucleoside-diphosphate reducta... | 392 | 9e-165 | 474 | 60 | 74 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IDA:UniProtKB.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; IDA:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0051290; P:protein heterotetramerization; IPI:UniProtKB. | 6 | P31350 | 389 | RIR2_HUMAN Ribonucleoside-diphosphate reducta... | 326 | 4e-164 | 473 | 69 | 81 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; NAS:UniProtKB.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome. | 7 | Q4KLN6 | 390 | RIR2_RAT Ribonucleoside-diphosphate reductase... | 326 | 5e-164 | 473 | 69 | 82 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0000278; P:mitotic cell cycle; IEP:RGD.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0006206; P:pyrimidine base metabolic process; IEP:RGD. | 8 | Q4R7Q7 | 389 | RIR2_MACFA Ribonucleoside-diphosphate reducta... | 326 | 8e-164 | 472 | 68 | 81 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 9 | Q60561 | 386 | RIR2_MESAU Ribonucleoside-diphosphate reducta... | 387 | 1e-161 | 466 | 60 | 74 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 10 | Q5R9G0 | 351 | RIR2B_PONAB Ribonucleoside-diphosphate reduct... | 325 | 5e-161 | 464 | 67 | 82 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 11 | Q7LG56 | 351 | RIR2B_HUMAN Ribonucleoside-diphosphate reduct... | 325 | 6e-161 | 463 | 67 | 82 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome. | 12 | Q4R741 | 351 | RIR2B_MACFA Ribonucleoside-diphosphate reduct... | 325 | 7e-161 | 463 | 66 | 82 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 13 | P07201 | 384 | RIR2_SPISO Ribonucleoside-diphosphate reducta... | 382 | 2e-160 | 463 | 59 | 74 | | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 14 | Q6PEE3 | 351 | RIR2B_MOUSE Ribonucleoside-diphosphate reduct... | 325 | 8e-160 | 461 | 66 | 82 | GO:0005739; C:mitochondrion; IC:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IDA:MGI.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009200; P:deoxyribonucleoside triphosphate metabolic process; IMP:MGI.::GO:0009263; P:deoxyribonucleotide biosynthetic process; IDA:MGI.::GO:0006281; P:DNA repair; IMP:MGI.::GO:0001822; P:kidney development; IMP:MGI.::GO:0006264; P:mitochondrial DNA replication; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0003014; P:renal system process; IMP:MGI.::GO:0006979; P:response to oxidative stress; IMP:MGI. | 15 | P48592 | 393 | RIR2_DROME Ribonucleoside-diphosphate reducta... | 324 | 2e-154 | 448 | 65 | 79 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:FlyBase.::GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 16 | O57175 | 319 | RIR2_VACCA Ribonucleoside-diphosphate reducta... | 324 | 2e-153 | 443 | 65 | 78 | | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 17 | P11158 | 319 | RIR2_VACCW Ribonucleoside-diphosphate reducta... | 324 | 1e-152 | 441 | 65 | 78 | | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 18 | P20493 | 319 | RIR2_VACCC Ribonucleoside-diphosphate reducta... | 324 | 3e-152 | 440 | 65 | 78 | | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 19 | P29883 | 319 | RIR2_VACCP Ribonucleoside-diphosphate reducta... | 324 | 5e-152 | 439 | 65 | 78 | | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 20 | P33799 | 319 | RIR2_VAR67 Ribonucleoside-diphosphate reducta... | 324 | 2e-150 | 436 | 64 | 78 | | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 21 | Q6Y657 | 333 | RIR2B_ARATH Putative ribonucleoside-diphospha... | 329 | 3e-146 | 425 | 63 | 76 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 22 | Q9DHU2 | 325 | RIR2_YLDV Ribonucleoside-diphosphate reductas... | 324 | 9e-146 | 424 | 62 | 77 | | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 23 | Q9LSD0 | 332 | RIR2C_ARATH Ribonucleoside-diphosphate reduct... | 328 | 1e-144 | 421 | 64 | 76 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006281; P:DNA repair; TAS:TAIR.::GO:0006260; P:DNA replication; IMP:TAIR.::GO:0007275; P:multicellular organismal development; IMP:TAIR.::GO:0012501; P:programmed cell death; IMP:TAIR.::GO:0051726; P:regulation of cell cycle; IMP:TAIR. | 24 | O15910 | 337 | RIR2_TRYBB Ribonucleoside-diphosphate reducta... | 341 | 1e-144 | 421 | 61 | 76 | | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 25 | P42170 | 381 | RIR2_CAEEL Ribonucleoside-diphosphate reducta... | 322 | 5e-144 | 421 | 62 | 78 | | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0016477; P:cell migration; IMP:WormBase.::GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0030728; P:ovulation; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase. | 26 | P42521 | 338 | RIR2_DICDI Ribonucleoside-diphosphate reducta... | 306 | 1e-143 | 419 | 65 | 80 | GO:0005634; C:nucleus; ISS:dictyBase.::GO:0005971; C:ribonucleoside-diphosphate reductase complex; ISS:dictyBase. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; ISS:dictyBase.::GO:0042493; P:response to drug; ISS:dictyBase. | 27 | Q8SRR2 | 325 | RIR2_ENCCU Ribonucleoside-diphosphate reducta... | 309 | 3e-143 | 417 | 65 | 80 | | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 28 | O46310 | 345 | RIR2_LEIAM Ribonucleoside-diphosphate reducta... | 327 | 1e-142 | 417 | 61 | 78 | | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 29 | P50651 | 341 | RIR2A_ARATH Ribonucleoside-diphosphate reduct... | 332 | 9e-142 | 414 | 61 | 75 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IDA:TAIR.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006281; P:DNA repair; TAS:TAIR.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IMP:TAIR.::GO:0051726; P:regulation of cell cycle; IMP:TAIR.::GO:0009259; P:ribonucleotide metabolic process; TAS:TAIR. | 30 | P49730 | 329 | RIR2_TOBAC Ribonucleoside-diphosphate reducta... | 326 | 1e-138 | 406 | 62 | 74 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 31 | P49723 | 345 | RIR4_YEAST Ribonucleoside-diphosphate reducta... | 347 | 9e-136 | 399 | 54 | 74 | GO:0005634; C:nucleus; IDA:SGD.::GO:0005971; C:ribonucleoside-diphosphate reductase complex; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IMP:SGD.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0051188; P:cofactor biosynthetic process; IMP:SGD.::GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.::GO:0009263; P:deoxyribonucleotide biosynthetic process; IDA:SGD.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW. |