rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P47068 | 1157 | BBC1_YEAST Myosin tail region-interacting pro... | 1157 | 0 | 2339 | 100 | 100 | GO:0030479; C:actin cortical patch; IDA:SGD. | | | | | | | | | | GO:0017024; F:myosin I binding; IPI:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IPI:SGD. | 2 | O42854 | 1611 | YFHH_SCHPO SH3 domain-containing protein C23A... | 152 | 9 | 34.3 | 39 | 47 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0017024; F:myosin I binding; ISS:PomBase. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:PomBase. | 3 | P12255 | 3590 | FHAB_BORPE Filamentous hemagglutinin OS=Borde... | 128 | 0.004 | 45.1 | 30 | 39 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 4 | P27951 | 1164 | BAG_STRAG IgA FC receptor OS=Streptococcus ag... | 86 | 0.0001 | 50.4 | 35 | 43 | GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 5 | Q91X43 | 789 | SH319_MOUSE SH3 domain-containing protein 19 ... | 49 | 0.41 | 38.5 | 33 | 53 | | | | | | | | | | | | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 6 | Q9Z0R6 | 1659 | ITSN2_MOUSE Intersectin-2 OS=Mus musculus (Mo... | 54 | 3.4 | 35.8 | 35 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 7 | O15230 | 3695 | LAMA5_HUMAN Laminin subunit alpha-5 OS=Homo s... | 98 | 0.003 | 45.8 | 35 | 43 | GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0005606; C:laminin-1 complex; IEA:InterPro.::GO:0043259; C:laminin-10 complex; IDA:UniProtKB.::GO:0043260; C:laminin-11 complex; TAS:BHF-UCL. | | | | | | | | | | GO:0005178; F:integrin binding; IDA:UniProtKB.::GO:0005198; F:structural molecule activity; IC:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; NAS:UniProtKB.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0008037; P:cell recognition; NAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.::GO:0045446; P:endothelial cell differentiation; NAS:UniProtKB.::GO:0048041; P:focal adhesion assembly; NAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL. | 8 | Q9Z0R4 | 1714 | ITSN1_MOUSE Intersectin-1 OS=Mus musculus (Mo... | 58 | 0.15 | 40 | 34 | 59 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019209; F:kinase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI. | 9 | Q9WVE9 | 1217 | ITSN1_RAT Intersectin-1 OS=Rattus norvegicus ... | 58 | 0.037 | 42 | 36 | 59 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; TAS:RGD. | 10 | O14302 | 886 | CYK3_SCHPO cytokinesis protein 3 OS=Schizosac... | 65 | 0.007 | 44.3 | 34 | 55 | GO:0005826; C:actomyosin contractile ring; NAS:PomBase.::GO:0051286; C:cell tip; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0033205; P:cell cycle cytokinesis; NAS:PomBase. | 11 | Q15811 | 1721 | ITSN1_HUMAN Intersectin-1 OS=Homo sapiens (Hu... | 58 | 0.035 | 42.4 | 36 | 59 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0032947; F:protein complex scaffold; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc. | 12 | Q9NZM3 | 1697 | ITSN2_HUMAN Intersectin-2 OS=Homo sapiens (Hu... | 54 | 0.12 | 40.4 | 39 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 13 | Q9WJB2 | 3960 | RPOA_PRRSR Replicase polyprotein 1ab OS=(PRRS... | 169 | 0.016 | 43.5 | 29 | 38 | GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro. | 14 | Q9R1Z8 | 733 | VINEX_MOUSE Vinexin OS=Mus musculus (Mouse). ... | 81 | 0.013 | 43.5 | 31 | 49 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0008134; F:transcription factor binding; IPI:MGI. | | | | | | | | | | GO:0031589; P:cell-substrate adhesion; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI. | 15 | O60504 | 671 | VINEX_HUMAN Vinexin OS=Homo sapiens (Human). ... | 57 | 0.013 | 43.5 | 37 | 53 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.::GO:0017166; F:vinculin binding; IPI:UniProtKB. | | | | | | | | | | GO:0006936; P:muscle contraction; TAS:Reactome.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:UniProtKB. | 16 | P06914 | 367 | CSP_PLAYO Circumsporozoite protein OS=Plasmod... | 73 | 0.14 | 39.7 | 40 | 40 | GO:0009986; C:cell surface; IEA:InterPro. | | | | | | | | | | | | | | | | | | | | | 17 | P42686 | 505 | SRK1_SPOLA Tyrosine-protein kinase isoform SR... | 55 | 0.029 | 42 | 33 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 18 | Q8IID4 | 5251 | DYHC2_PLAF7 Dynein heavy chain-like protein P... | 153 | 0.032 | 42.4 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0003777; F:microtubule motor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007018; P:microtubule-based movement; ISS:UniProtKB. | 19 | P42690 | 506 | SRK4_SPOLA Tyrosine-protein kinase isoform SR... | 55 | 0.031 | 42 | 33 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 20 | B0KWR6 | 1235 | SFI1_CALJA Protein SFI1 homolog OS=Callithrix... | 106 | 0.031 | 42.4 | 33 | 49 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0019902; F:phosphatase binding; ISS:UniProtKB. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 21 | Q9NYB9 | 513 | ABI2_HUMAN Abl interactor 2 OS=Homo sapiens (... | 56 | 0.063 | 40.8 | 39 | 55 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; TAS:UniProtKB.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; NAS:UniProtKB.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI. | 22 | Q9JLQ0 | 637 | CD2AP_MOUSE CD2-associated protein OS=Mus mus... | 82 | 0.064 | 41.2 | 38 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 23 | O77775 | 527 | NCF2_BOVIN Neutrophil cytosol factor 2 OS=Bos... | 56 | 0.081 | 40.8 | 43 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 24 | Q9VT65 | 925 | CANB_DROME Calpain-B OS=Drosophila melanogast... | 129 | 0.18 | 39.7 | 36 | 43 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IDA:UniProtKB. | | | | | | | | | | GO:0016540; P:protein autoprocessing; TAS:FlyBase.::GO:0006508; P:proteolysis; IDA:UniProtKB. | 25 | Q9QWY8 | 1147 | ASAP1_MOUSE Arf-GAP with SH3 domain, ANK repe... | 58 | 0.095 | 40.8 | 34 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 26 | O97902 | 1129 | ASAP1_BOVIN Arf-GAP with SH3 domain, ANK repe... | 58 | 0.11 | 40.4 | 33 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 27 | Q9ULH1 | 1129 | ASAP1_HUMAN Arf-GAP with SH3 domain, ANK repe... | 58 | 0.12 | 40.4 | 34 | 57 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 28 | Q5HYK7 | 790 | SH319_HUMAN SH3 domain-containing protein 19 ... | 56 | 0.3 | 38.9 | 34 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0070064; F:proline-rich region binding; IPI:BHF-UCL. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB. | 29 | Q6BRR2 | 1265 | SEC31_DEBHA Protein transport protein SEC31 O... | 112 | 0.35 | 38.9 | 31 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. | 30 | Q3UIL6 | 1118 | PKHA7_MOUSE Pleckstrin homology domain-contai... | 128 | 0.42 | 38.5 | 31 | 38 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005915; C:zonula adherens; ISS:UniProtKB. | | | | | | | | | | GO:0070097; F:delta-catenin binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0090136; P:epithelial cell-cell adhesion; ISS:UniProtKB.::GO:0045218; P:zonula adherens maintenance; ISS:UniProtKB. | 31 | O43150 | 1006 | ASAP2_HUMAN Arf-GAP with SH3 domain, ANK repe... | 58 | 0.49 | 38.1 | 38 | 50 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. |