Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YJL013C
Length:
515
Number of sequences:
5887
Description:
YJL013C MAD3 SGDID:S000003550, Chr X from 411040-409493, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the spindle-assembly checkpoint complex, which delays anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P47074    515   MAD3_YEAST Spindle assembly checkpoint compon...5150     1055     100     100GO:0033597; C:mitotic checkpoint complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0032837; P:distributive segregation; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IGI:SGD.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:SGD.
2P41695    1021   BUB1_YEAST Checkpoint serine/threonine-protei...3532e-48     184     36     56GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:SGD.::GO:0034501; P:protein localization to kinetochore; IMP:SGD.::GO:0031134; P:sister chromatid biorientation; IMP:SGD.
3O59767    310   MAD3_SCHPO Mitotic spindle checkpoint compone...1876e-23     102     35     56GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0033597; C:mitotic checkpoint complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IGI:PomBase.::GO:0051444; P:negative regulation of ubiquitin-protein ligase activity; TAS:PomBase.
4O60566    1050   BUB1B_HUMAN Mitotic checkpoint serine/threoni...1751e-19     96.3     36     51GO:0005680; C:anaphase-promoting complex; TAS:ProtInc.::GO:0000940; C:condensed chromosome outer kinetochore; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0051233; C:spindle midzone; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; IPI:UniProtKB.::GO:0007051; P:spindle organization; NAS:UniProtKB.
5Q9Z1S0    1052   BUB1B_MOUSE Mitotic checkpoint serine/threoni...1751e-18     93.2     35     49GO:0000940; C:condensed chromosome outer kinetochore; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007091; P:mitotic metaphase/anaphase transition; IGI:MGI.
6Q54CV5    1306   BUB1_DICDI Probable inactive serine/threonine...1839e-18     90.9     36     55GO:0005680; C:anaphase-promoting complex; ISS:dictyBase.
GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
GO:0007093; P:mitotic cell cycle checkpoint; ISS:dictyBase.
7O43683    1085   BUB1_HUMAN Mitotic checkpoint serine/threonin...1400.00000002     60.8     26     49GO:0000777; C:condensed chromosome kinetochore; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:ProtInc.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0007063; P:regulation of sister chromatid cohesion; IDA:UniProtKB.
8O08901    1058   BUB1_MOUSE Mitotic checkpoint serine/threonin...1280.0000005     56.2     28     49GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0000780; C:condensed nuclear chromosome, centromeric region; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007063; P:regulation of sister chromatid cohesion; ISS:UniProtKB.::GO:0071173; P:spindle assembly checkpoint; IDA:UniProtKB.
9O94751    1044   BUB1_SCHPO Checkpoint serine/threonine-protei...1360.0000008     55.8     30     51GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0072371; F:histone kinase activity (H2A-S121 specific); IDA:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0051455; P:attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation; IMP:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051754; P:meiotic sister chromatid cohesion, centromeric; IGI:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:PomBase.::GO:0034501; P:protein localization to kinetochore; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
10Q9DEI1    4146   PRKDC_XENLA DNA-dependent protein kinase cata...1443.4     34.3     27     44GO:0070419; C:nonhomologous end joining complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004677; F:DNA-dependent protein kinase activity; IEA:InterPro.
GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:InterPro.
records
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