Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIR039C
Length:
537
Number of sequences:
5887
Description:
YIR039C YPS6 SGDID:S000001478, Chr IX from 432111-430498, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative GPI-anchored aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121P10602    389   CARP1_RHINI Rhizopuspepsin-1 OS=Rhizopus nive...3710.000002     53.9     25     42
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
122P08424    402   RENI_RAT Renin OS=Rattus norvegicus (Rat). GN...3830.000005     52.4     23     39GO:0044444; C:cytoplasmic part; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0005159; F:insulin-like growth factor receptor binding; IDA:RGD.
GO:0002003; P:angiotensin maturation; IDA:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0070305; P:response to cGMP; IDA:RGD.::GO:0042493; P:response to drug; IDA:RGD.::GO:0006950; P:response to stress; IDA:RGD.
123C5FEK4    377   CTSD_ARTOC Probable aspartic-type endopeptida...3180.000007     52     26     42GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
124Q9LS40    500   ASPG1_ARATH Protein ASPARTIC PROTEASE IN GUAR...1530.000008     52     28     41GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:InterPro.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.
125P43232    392   CARP5_RHINI Rhizopuspepsin-5 OS=Rhizopus nive...3680.00001     51.2     22     40
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
126P07339    412   CATD_HUMAN Cathepsin D OS=Homo sapiens (Human...3900.00002     50.8     22     40GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc.
GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
127P14091    401   CATE_HUMAN Cathepsin E OS=Homo sapiens (Human...3930.00002     50.8     23     39GO:0005768; C:endosome; IDA:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.
GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.::GO:0007586; P:digestion; TAS:ProtInc.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
128Q766C2    438   NEP2_NEPGR Aspartic proteinase nepenthesin-2 ...4100.00002     50.8     21     37GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
129Q766C3    437   NEP1_NEPGR Aspartic proteinase nepenthesin-1 ...1680.00002     50.4     26     46GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
130Q4LAL9    410   CATD_CANFA Cathepsin D OS=Canis familiaris (D...3890.00002     50.4     24     40GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
131Q4WZS3    428   Y5950_ASPFU Putative aspergillopepsin A-like ...3110.00009     48.5     26     38GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
132P56819    501   BACE1_RAT Beta-secretase 1 OS=Rattus norvegic...4040.0001     48.1     23     38GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.
133P56818    501   BACE1_MOUSE Beta-secretase 1 OS=Mus musculus ...4040.0001     48.1     23     38GO:0030424; C:axon; IDA:MGI.::GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.
134C5FZ57    430   Y7979_ARTOC Putative aspergillopepsin A-like ...3690.0002     47.4     23     38GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
135P81214    395   CARP_SYNRA Syncephapepsin OS=Syncephalastrum ...3740.0003     46.6     23     39
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
136Q9MZS8    365   CATD_SHEEP Cathepsin D OS=Ovis aries (Sheep)....2310.0004     46.6     25     39GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
137Q9XFX4    506   CARDB_CYNCA Procardosin-B OS=Cynara carduncul...2260.0005     46.6     25     39GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0000326; C:protein storage vacuole; IEA:UniProtKB-SubCell.::GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
138P56817    501   BACE1_HUMAN Beta-secretase 1 OS=Homo sapiens ...4040.0006     46.2     23     38GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.::GO:0008798; F:beta-aspartyl-peptidase activity; TAS:ProtInc.::GO:0019899; F:enzyme binding; IPI:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; IDA:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; TAS:UniProtKB.
139D4DGR1    430   Y6366_TRIVH Probable aspartic-type endopeptid...2830.0006     45.8     25     42GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
140P00799    430   CARP_RHIMI Mucorpepsin OS=Rhizomucor miehei. ...3870.001     45.4     25     38
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
141Q9XFX3    504   CARDA_CYNCA Procardosin-A OS=Cynara carduncul...2240.001     45.4     24     40GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0000326; C:protein storage vacuole; IEA:UniProtKB-SubCell.::GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
142Q42456    509   ASPR1_ORYSJ Aspartic proteinase oryzasin-1 OS...2220.001     45.1     23     41
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
143Q2HJ40    501   BACE1_BOVIN Beta-secretase 1 OS=Bos taurus (B...4040.001     44.7     22     38GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.
144Q6IE75    514   BACE2_RAT Beta-secretase 2 OS=Rattus norvegic...2780.002     44.7     24     40GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0042985; P:negative regulation of amyloid precursor protein biosynthetic process; ISS:UniProtKB.
145P00795    345   CATD_PIG Cathepsin D OS=Sus scrofa (Pig). GN=...3810.002     44.3     23     39GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
146D4AT39    430   Y7403_ARTBC Probable aspartic-type endopeptid...2830.002     44.3     25     41GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
147P52115    400   RENI_SHEEP Renin OS=Ovis aries (Sheep). GN=RE...3910.004     43.1     24     38GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
148Q9LHE3    470   ASPG2_ARATH Protein ASPARTIC PROTEASE IN GUAR...1390.007     42.7     24     42
GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
149D4DE18    401   Y5382_TRIVH Probable aspartic-type endopeptid...1730.007     42.4     25     42GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
150P40782    473   CYPR1_CYNCA Cyprosin OS=Cynara cardunculus (C...2220.009     42.4     23     41
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
151Q9S9K4    475   ASPL2_ARATH Aspartic proteinase-like protein ...1250.011     42     21     46GO:0046658; C:anchored to plasma membrane; IDA:TAIR.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
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