Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIR037W
Length:
163
Number of sequences:
5887
Description:
YIR037W HYR1 SGDID:S000001476, Chr IX from 423128-423619, Genome Release 64-1-1, Verified ORF, "Thiol peroxidase that functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q4AEH4    226   GPX3_MACFU Glutathione peroxidase 3 OS=Macaca...1632e-22     94.4     39     50GO:0005615; C:extracellular space; ISS:UniProtKB.
GO:0004602; F:glutathione peroxidase activity; ISS:UniProtKB.::GO:0008430; F:selenium binding; ISS:UniProtKB.
GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro.
92P23764    226   GPX3_RAT Glutathione peroxidase 3 OS=Rattus n...1632e-22     94.4     39     50GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0043295; F:glutathione binding; IDA:RGD.::GO:0004602; F:glutathione peroxidase activity; ISS:UniProtKB.::GO:0008430; F:selenium binding; ISS:UniProtKB.
GO:0007565; P:female pregnancy; IEP:RGD.::GO:0006749; P:glutathione metabolic process; IDA:RGD.::GO:0042744; P:hydrogen peroxide catabolic process; IDA:RGD.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0002238; P:response to molecule of fungal origin; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010269; P:response to selenium ion; IEP:RGD.
93P04041    201   GPX1_RAT Glutathione peroxidase 1 OS=Rattus n...1722e-22     93.6     35     47GO:0005829; C:cytosol; TAS:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0043295; F:glutathione binding; IDA:RGD.::GO:0004602; F:glutathione peroxidase activity; IDA:RGD.::GO:0047066; F:phospholipid-hydroperoxide glutathione peroxidase activity; IMP:RGD.::GO:0008430; F:selenium binding; IMP:RGD.
GO:0007568; P:aging; IEP:RGD.::GO:0006749; P:glutathione metabolic process; IDA:RGD.::GO:0042744; P:hydrogen peroxide catabolic process; IDA:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0051593; P:response to folic acid; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0006982; P:response to lipid hydroperoxide; IMP:RGD.::GO:0035094; P:response to nicotine; IEP:RGD.::GO:0010269; P:response to selenium ion; IEP:RGD.
94P11352    201   GPX1_MOUSE Glutathione peroxidase 1 OS=Mus mu...1723e-22     93.6     35     48GO:0005739; C:mitochondrion; IDA:MGI.
GO:0004602; F:glutathione peroxidase activity; IDA:MGI.
GO:0060055; P:angiogenesis involved in wound healing; IMP:MGI.::GO:0043534; P:blood vessel endothelial cell migration; IMP:MGI.::GO:0001885; P:endothelial cell development; IMP:MGI.::GO:0045444; P:fat cell differentiation; IMP:MGI.::GO:0060047; P:heart contraction; IMP:MGI.::GO:0042744; P:hydrogen peroxide catabolic process; IMP:MGI.::GO:0008631; P:induction of apoptosis by oxidative stress; IMP:MGI.::GO:0051450; P:myoblast proliferation; IMP:MGI.::GO:0014902; P:myotube differentiation; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:MGI.::GO:0018158; P:protein oxidation; IMP:MGI.::GO:0043523; P:regulation of neuron apoptotic process; IMP:MGI.::GO:0033194; P:response to hydroperoxide; IMP:MGI.::GO:0009636; P:response to toxin; IMP:MGI.::GO:0009410; P:response to xenobiotic stimulus; IMP:MGI.::GO:0007605; P:sensory perception of sound; IMP:MGI.::GO:0048741; P:skeletal muscle fiber development; IMP:MGI.::GO:0043403; P:skeletal muscle tissue regeneration; IMP:MGI.::GO:0006641; P:triglyceride metabolic process; IMP:MGI.::GO:0042311; P:vasodilation; IMP:MGI.
95Q4AEH3    226   GPX3_CEBAP Glutathione peroxidase 3 OS=Cebus ...1633e-22     93.6     39     50GO:0005615; C:extracellular space; ISS:UniProtKB.
GO:0004602; F:glutathione peroxidase activity; ISS:UniProtKB.::GO:0008430; F:selenium binding; ISS:UniProtKB.
GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEA:InterPro.
96P35666    223   GPXC_WUCBA Cuticular glutathione peroxidase O...1673e-22     93.6     33     53GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
97Q4AEH8    190   GPX2_MACFU Glutathione peroxidase 2 OS=Macaca...1812e-21     91.3     33     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
98Q0EF98    190   GPX2_CALJA Glutathione peroxidase 2 OS=Callit...1812e-21     90.9     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
99P52033    221   GPXC_DIRIM Glutathione peroxidase OS=Dirofila...1632e-21     91.3     34     52GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
100P46412    226   GPX3_MOUSE Glutathione peroxidase 3 OS=Mus mu...1634e-21     90.5     39     50GO:0005615; C:extracellular space; ISS:UniProtKB.
GO:0004602; F:glutathione peroxidase activity; ISS:UniProtKB.::GO:0008430; F:selenium binding; ISS:UniProtKB.
GO:0042744; P:hydrogen peroxide catabolic process; IDA:MGI.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
101Q865R2    201   GPX1_MACFU Glutathione peroxidase 1 OS=Macaca...1725e-21     90.1     34     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
102Q4AEI3    201   GPX1_PONPY Glutathione peroxidase 1 OS=Pongo ...1726e-21     89.7     34     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
103P07203    203   GPX1_HUMAN Glutathione peroxidase 1 OS=Homo s...1726e-21     89.7     34     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:BHF-UCL.
GO:0004866; F:endopeptidase inhibitor activity; IDA:BHF-UCL.::GO:0004602; F:glutathione peroxidase activity; IDA:BHF-UCL.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
GO:0006916; P:anti-apoptosis; IMP:BHF-UCL.::GO:0045454; P:cell redox homeostasis; IDA:BHF-UCL.::GO:0006749; P:glutathione metabolic process; IDA:BHF-UCL.::GO:0060047; P:heart contraction; IMP:BHF-UCL.::GO:0042744; P:hydrogen peroxide catabolic process; IDA:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.::GO:0006144; P:purine base metabolic process; TAS:Reactome.::GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome.::GO:0040029; P:regulation of gene expression, epigenetic; IDA:BHF-UCL.::GO:0033599; P:regulation of mammary gland epithelial cell proliferation; IMP:BHF-UCL.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:BHF-UCL.::GO:0001836; P:release of cytochrome c from mitochondria; IMP:BHF-UCL.::GO:0010269; P:response to selenium ion; IMP:BHF-UCL.::GO:0009650; P:UV protection; IMP:BHF-UCL.
104P00435    205   GPX1_BOVIN Glutathione peroxidase 1 OS=Bos ta...1727e-21     89.7     34     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
105Q8MJ14    206   GPX1_PIG Glutathione peroxidase 1 OS=Sus scro...1728e-21     89.4     34     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
106Q4AEI2    201   GPX1_HYLLA Glutathione peroxidase 1 OS=Hyloba...1721e-20     89     33     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
107Q98234    220   GPX_MCV1 Glutathione peroxidase OS=Molluscum ...1704e-20     87.8     33     47
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
108Q0EFA0    201   GPX1_PANTR Glutathione peroxidase 1 OS=Pan tr...1728e-20     86.7     33     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
109P11909    200   GPX1_RABIT Glutathione peroxidase 1 OS=Orycto...1727e-18     81.3     31     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
110Q4AEI1    201   GPX1_CEBAP Glutathione peroxidase 1 OS=Cebus ...1720.000000000000006     72.8     30     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
111Q0EF99    201   GPX1_CALJA Glutathione peroxidase 1 OS=Callit...1720.000000000000006     72.8     30     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
112P81087    17   GPX4_PINPS Glutathione peroxidase homolog OS=...170.19     32.7     71     82
GO:0004602; F:glutathione peroxidase activity; IEA:EC.
GO:0006979; P:response to oxidative stress; IEA:InterPro.
113Q10801    695   DIPZ_MYCTU Protein dipZ OS=Mycobacterium tube...800.3     34.7     30     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0016209; F:antioxidant activity; IEA:InterPro.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0017004; P:cytochrome complex assembly; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
114P59960    695   DIPZ_MYCBO Protein dipZ OS=Mycobacterium bovi...800.3     34.7     30     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016209; F:antioxidant activity; IEA:InterPro.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0017004; P:cytochrome complex assembly; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
115Q81SZ9    173   RESA_BACAN Thiol-disulfide oxidoreductase res...1350.44     33.9     29     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016209; F:antioxidant activity; IEA:InterPro.::GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.
GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
116A0RBT0    173   RESA_BACAH Thiol-disulfide oxidoreductase res...1350.44     33.9     29     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016209; F:antioxidant activity; IEA:InterPro.::GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.
GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
117Q81FU5    173   RESA_BACCR Thiol-disulfide oxidoreductase res...1350.68     33.1     29     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016209; F:antioxidant activity; IEA:InterPro.::GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.
GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
118Q8HZJ4    279   CABP4_BOVIN Calcium-binding protein 4 OS=Bos ...591.8     32     31     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
119Q9FKC6    117   SUMO6_ARATH Putative small ubiquitin-related ...564.4     30     30     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
records
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