Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIR033W
Length:
1113
Number of sequences:
5887
Description:
YIR033W MGA2 SGDID:S000001472, Chr IX from 416124-419465, Genome Release 64-1-1, Verified ORF, "ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40578    1113   MGA2_YEAST Protein MGA2 OS=Saccharomyces cere...11130     2289     100     100GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0070417; P:cellular response to cold; IMP:SGD.::GO:0048255; P:mRNA stabilization; IMP:SGD.::GO:0061399; P:positive regulation of transcription from RNA polymerase II promoter in response to cobalt ion; IMP:SGD.::GO:0061419; P:positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; IMP:SGD.::GO:0036083; P:positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter; IGI:SGD.
2P35210    1082   SPT23_YEAST Protein SPT23 OS=Saccharomyces ce...10580     619     39     56GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0003677; F:DNA binding; IPI:SGD.
GO:0070417; P:cellular response to cold; IGI:SGD.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IGI:SGD.::GO:0036083; P:positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter; IGI:SGD.
3O13987    1151   YEG5_SCHPO Ankyrin and IPT/TIG repeat-contain...2633e-26     120     30     49GO:0000324; C:fungal-type vacuole; IDA:PomBase.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IC:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0045723; P:positive regulation of fatty acid biosynthetic process; ISS:PomBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:PomBase.
4E5RJM6    399   ANR65_HUMAN Ankyrin repeat domain-containing ...740.12     39.7     28     50
5A6QPE7    395   ANR65_BOVIN Ankyrin repeat domain-containing ...791.1     36.6     30     49
6A2VDR2    282   ACBD6_BOVIN Acyl-CoA-binding domain-containin...930.00000002     60.5     38     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
7Q9BXW6    950   OSBL1_HUMAN Oxysterol-binding protein-related...820.00000005     61.2     39     59GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005543; F:phospholipid binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008203; P:cholesterol metabolic process; NAS:UniProtKB.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB.
8Q8K4M9    950   OSBL1_RAT Oxysterol-binding protein-related p...850.0000002     59.3     38     58GO:0005770; C:late endosome; ISS:UniProtKB.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
9Q66JD7    286   ACBD6_XENTR Acyl-CoA-binding domain-containin...1060.0000002     57.8     34     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
10Q9TU71    319   ANKR1_RABIT Ankyrin repeat domain-containing ...1230.0000003     57.4     31     51
11Q02989    1411   LITA_LATTR Alpha-latroinsectotoxin-Lt1a OS=(L...595.9     34.7     29     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0072556; C:other organism presynaptic membrane; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
12Q91XL9    950   OSBL1_MOUSE Oxysterol-binding protein-related...850.0000003     58.5     38     58GO:0005770; C:late endosome; ISS:UniProtKB.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
13Q8C8R3    3898   ANK2_MOUSE Ankyrin-2 OS=Mus musculus (Mouse)....672.8     35.8     30     48GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0060048; P:cardiac muscle contraction; IMP:MGI.::GO:0034394; P:protein localization at cell surface; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
14Q9BR61    282   ACBD6_HUMAN Acyl-CoA-binding domain-containin...930.0000006     55.8     37     54GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
15Q01484    3957   ANK2_HUMAN Ankyrin-2 OS=Homo sapiens (Human)....673.1     35.8     30     48GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007165; P:signal transduction; IEA:InterPro.
16Q4V869    286   ACBD6_XENLA Acyl-CoA-binding domain-containin...810.0000007     55.8     36     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
17Q9CR42    319   ANKR1_MOUSE Ankyrin repeat domain-containing ...1230.0000008     55.8     30     50GO:0031674; C:I band; IDA:BHF-UCL.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0031432; F:titin binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI.
GO:0035690; P:cellular response to drug; IDA:UniProtKB.::GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB.
18Q5REW9    1050   ANR27_PONAB Ankyrin repeat domain-containing ...1410.014     43.1     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
19Q8UVC3    1106   INVS_CHICK Inversin OS=Gallus gallus (Chicken...662.4     36.2     33     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
20Q5RJK8    282   ACBD6_RAT Acyl-CoA-binding domain-containing ...634     34.7     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
21Q8R560    319   ANKR1_RAT Ankyrin repeat domain-containing pr...1230.000002     54.7     30     50GO:0031674; C:I band; IDA:BHF-UCL.
GO:0071456; P:cellular response to hypoxia; IEP:RGD.::GO:0071407; P:cellular response to organic cyclic compound; IEP:RGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0010976; P:positive regulation of neuron projection development; IMP:RGD.
22Q865U8    319   ANKR1_PIG Ankyrin repeat domain-containing pr...1230.000002     54.7     31     50GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0003779; F:actin binding; IPI:BHF-UCL.::GO:0031432; F:titin binding; IPI:BHF-UCL.
23Q96NW4    1050   ANR27_HUMAN Ankyrin repeat domain-containing ...1410.007     44.3     28     46GO:0005769; C:early endosome; IDA:MGI.::GO:0005764; C:lysosome; IDA:LIFEdb.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.
GO:0045022; P:early endosome to late endosome transport; IDA:MGI.
24E1C656    942   HACE1_CHICK E3 ubiquitin-protein ligase HACE1...700.044     41.6     29     59GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
25Q3UMR0    1048   ANR27_MOUSE Ankyrin repeat domain-containing ...1711.6     36.6     25     40
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
26Q978J0    189   Y1425_THEVO Putative ankyrin repeat protein T...878.1     33.1     32     46
27Q12955    4377   ANK3_HUMAN Ankyrin-3 OS=Homo sapiens (Human)....732.2     36.2     29     48GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045184; P:establishment of protein localization; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
28F8W2M1    904   HACE1_DANRE E3 ubiquitin-protein ligase HACE1...1600.01     43.9     28     43GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
29Q15327    319   ANKR1_HUMAN Ankyrin repeat domain-containing ...1230.000007     53.1     30     50GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0031674; C:I band; ISS:BHF-UCL.
GO:0003677; F:DNA binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0002039; F:p53 binding; IPI:BHF-UCL.::GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0031432; F:titin binding; IPI:BHF-UCL.::GO:0003714; F:transcription corepressor activity; TAS:BHF-UCL.
GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0071347; P:cellular response to interleukin-1; IDA:BHF-UCL.::GO:0071222; P:cellular response to lipopolysaccharide; IDA:BHF-UCL.::GO:0071260; P:cellular response to mechanical stimulus; IDA:UniProtKB.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.::GO:0071356; P:cellular response to tumor necrosis factor; IDA:BHF-UCL.::GO:2000279; P:negative regulation of DNA biosynthetic process; IMP:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.::GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB.::GO:0035994; P:response to muscle stretch; IMP:BHF-UCL.::GO:0045214; P:sarcomere organization; NAS:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
30Q86SG2    305   ANR23_HUMAN Ankyrin repeat domain-containing ...670.27     38.5     36     52GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0031432; F:titin binding; IPI:BHF-UCL.
31Q7XUW4    719   KOR2_ORYSJ Potassium channel KOR2 OS=Oryza sa...1070.000008     53.9     33     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
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