Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIR033W
Length:
1113
Number of sequences:
5887
Description:
YIR033W MGA2 SGDID:S000001472, Chr IX from 416124-419465, Genome Release 64-1-1, Verified ORF, "ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
421Q9BYH8    718   IKBZ_HUMAN NF-kappa-B inhibitor zeta OS=Homo ...1160.21     39.3     23     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
422Q1AAU6    1144   ASAP1_RAT Arf-GAP with SH3 domain, ANK repeat...770.21     39.7     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
423O08764    1009   ABTB2_RAT Ankyrin repeat and BTB/POZ domain-c...330.22     39.3     45     70
GO:0003677; F:DNA binding; IEA:InterPro.
424Q9QWY8    1147   ASAP1_MOUSE Arf-GAP with SH3 domain, ANK repe...770.22     39.3     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
425Q9ULT8    2610   HECD1_HUMAN E3 ubiquitin-protein ligase HECTD...830.22     39.7     34     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
426Q69ZR2    2618   HECD1_MOUSE E3 ubiquitin-protein ligase HECTD...830.22     39.7     34     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0001843; P:neural tube closure; IMP:UniProtKB.
427Q8IVF6    992   AN18A_HUMAN Ankyrin repeat domain-containing ...730.24     39.3     32     47
428Q8WXK3    278   ASB13_HUMAN Ankyrin repeat and SOCS box prote...820.51     37.4     28     50
GO:0005515; F:protein binding; IPI:IntAct.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
429Q8WXI3    467   ASB10_HUMAN Ankyrin repeat and SOCS box prote...580.33     38.5     34     57
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
430Q08353    314   IKBA_PIG NF-kappa-B inhibitor alpha OS=Sus sc...734.3     34.7     33     51GO:0005634; C:nucleus; ISS:AgBase.
GO:0051059; F:NF-kappaB binding; ISS:AgBase.::GO:0008139; F:nuclear localization sequence binding; ISS:AgBase.::GO:0031625; F:ubiquitin protein ligase binding; ISS:AgBase.
GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:AgBase.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:AgBase.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:AgBase.::GO:0000060; P:protein import into nucleus, translocation; ISS:AgBase.::GO:0042127; P:regulation of cell proliferation; ISS:AgBase.::GO:0043330; P:response to exogenous dsRNA; ISS:AgBase.
431Q8L746    586   NPR3_ARATH Regulatory protein NPR3 OS=Arabido...1190.24     39.3     26     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0009816; P:defense response to bacterium, incompatible interaction; IMP:TAIR.::GO:0009817; P:defense response to fungus, incompatible interaction; IMP:TAIR.
432Q5EA33    238   ANR49_BOVIN Ankyrin repeat domain-containing ...750.25     38.1     29     45
433Q74ZH9    1321   GDE1_ASHGO Glycerophosphodiester phosphodiest...920.25     39.3     29     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:EC.::GO:0004629; F:phospholipase C activity; IEA:InterPro.
GO:0006071; P:glycerol metabolic process; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006629; P:lipid metabolic process; IEA:InterPro.
434Q86U10    573   LPP60_HUMAN 60 kDa lysophospholipase OS=Homo ...740.25     38.9     28     50
GO:0003847; F:1-alkyl-2-acetylglycerophosphocholine esterase activity; IEA:EC.::GO:0004067; F:asparaginase activity; IEA:EC.::GO:0004622; F:lysophospholipase activity; IEA:EC.
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
435Q63746    314   IKBA_RAT NF-kappa-B inhibitor alpha OS=Rattus...781.1     36.6     29     54GO:0005829; C:cytosol; IDA:RGD.::GO:0033256; C:I-kappaB/NF-kappaB complex; IC:RGD.::GO:0005634; C:nucleus; IDA:RGD.
GO:0031072; F:heat shock protein binding; IPI:RGD.::GO:0051059; F:NF-kappaB binding; IPI:RGD.
GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IMP:RGD.
436Q9BQW3    602   COE4_HUMAN Transcription factor COE4 OS=Homo ...870.27     38.9     31     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
437Q1RK13    826   Y220_RICBR Putative ankyrin repeat protein RB...1013.9     35.4     31     38
438Q8VHA6    467   ASB18_MOUSE Ankyrin repeat and SOCS box prote...410.27     38.9     41     61
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
439Q8TAK5    448   GABP2_HUMAN GA-binding protein subunit beta-2...530.28     38.9     32     57GO:0005634; C:nucleus; IDA:MGI.
GO:0046982; F:protein heterodimerization activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
440Q5DW34    1296   EHMT1_MOUSE Histone-lysine N-methyltransferas...680.28     39.3     35     50GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0046976; F:histone methyltransferase activity (H3-K27 specific); IDA:UniProtKB.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006306; P:DNA methylation; IDA:UniProtKB.::GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0018027; P:peptidyl-lysine dimethylation; IMP:UniProtKB.::GO:0018026; P:peptidyl-lysine monomethylation; IMP:UniProtKB.
441P19838    968   NFKB1_HUMAN Nuclear factor NF-kappa-B p105 su...800.28     38.9     33     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0033256; C:I-kappaB/NF-kappaB complex; TAS:BHF-UCL.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB.
GO:0006916; P:anti-apoptosis; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071347; P:cellular response to interleukin-1; IEP:BHF-UCL.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0010956; P:negative regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0032269; P:negative regulation of cellular protein metabolic process; IC:BHF-UCL.::GO:0032375; P:negative regulation of cholesterol transport; IC:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0010957; P:negative regulation of vitamin D biosynthetic process; IC:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:1900127; P:positive regulation of hyaluronan biosynthetic process; IDA:UniProtKB.::GO:0010884; P:positive regulation of lipid storage; IC:BHF-UCL.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IC:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:UniProtKB.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
442B1AK53    854   ESPN_HUMAN Espin OS=Homo sapiens (Human). GN=...500.41     38.5     40     56GO:0005903; C:brush border; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0031941; C:filamentous actin; ISS:UniProtKB.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; ISS:UniProtKB.
GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.
443Q9VCA8    4001   ANKHM_DROME Ankyrin repeat and KH domain-cont...672.6     36.2     34     54GO:0005811; C:lipid particle; IDA:FlyBase.
GO:0019887; F:protein kinase regulator activity; IGI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0019730; P:antimicrobial humoral response; IMP:FlyBase.::GO:0051298; P:centrosome duplication; IMP:FlyBase.::GO:0001751; P:compound eye photoreceptor cell differentiation; IMP:FlyBase.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IGI:FlyBase.
444Q811D2    1581   ANR26_MOUSE Ankyrin repeat domain-containing ...630.29     38.9     30     48
445Q9J4Z6    668   V244_FOWPN Putative ankyrin repeat protein FP...1083.6     35.4     29     43
446Q8VBX0    278   ASB13_MOUSE Ankyrin repeat and SOCS box prote...820.51     37.4     28     50
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
447Q0V8G2    447   GABP2_BOVIN GA-binding protein subunit beta-2...530.33     38.5     32     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
448Q7TQI7    1024   ABTB2_MOUSE Ankyrin repeat and BTB/POZ domain...330.31     38.9     42     70
GO:0003677; F:DNA binding; IEA:InterPro.
449Q8N961    839   ABTB2_HUMAN Ankyrin repeat and BTB/POZ domain...370.32     38.9     38     68
GO:0003677; F:DNA binding; IEA:InterPro.
GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
450Q9D2X0    183   ANR39_MOUSE Ankyrin repeat domain-containing ...730.32     37.4     32     52
451Q7T3P8    618   FEM1C_DANRE Protein fem-1 homolog C OS=Danio ...650.33     38.5     34     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
records
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