UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YIR033W

Length:

1113

Number of sequences:

5887

Description:

YIR033W MGA2 SGDID:S000001472, Chr IX from 416124-419465, Genome Release 64-1-1, Verified ORF, "ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
301	Q8IZ07	590	AN13A_HUMAN Ankyrin repeat domain-containing ...	62	0.024	42.4	35	52
302	Q8VE42	238	ANR49_MOUSE Ankyrin repeat domain-containing ...	101	0.024	41.6	28	45
303	Q8CGN4	1759	BCOR_MOUSE BCL-6 corepressor OS=Mus musculus ...	89	0.024	42.7	30	54
									GO:0005515; F:protein binding; IPI:MGI.::GO:0003714; F:transcription corepressor activity; IPI:MGI.
									GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
304	B7ZRI2	580	COE2B_XENLA Transcription factor coe2-B OS=Xe...	72	0.026	42.4	38	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
305	Q28FJ2	163	ANR37_XENTR Ankyrin repeat domain-containing ...	79	0.026	40.4	28	51
306	Q6W2J9	1755	BCOR_HUMAN BCL-6 corepressor OS=Homo sapiens ...	89	0.026	42.4	30	54	GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0031072; F:heat shock protein binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IMP:UniProtKB.
									GO:0007507; P:heart development; IMP:UniProtKB.::GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.::GO:0030502; P:negative regulation of bone mineralization; IMP:UniProtKB.::GO:0000415; P:negative regulation of histone H3-K36 methylation; IMP:UniProtKB.::GO:0051572; P:negative regulation of histone H3-K4 methylation; IMP:UniProtKB.::GO:0070171; P:negative regulation of tooth mineralization; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0042476; P:odontogenesis; IMP:UniProtKB.::GO:0060021; P:palate development; IMP:UniProtKB.::GO:0065001; P:specification of axis polarity; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
307	Q9EST8	728	IKBZ_MOUSE NF-kappa-B inhibitor zeta OS=Mus m...	132	0.027	42.4	23	45	GO:0005634; C:nucleus; IDA:MGI.
									GO:0006954; P:inflammatory response; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
308	Q923M0	524	PP16A_MOUSE Protein phosphatase 1 regulatory ...	104	0.03	42	28	49	GO:0005829; C:cytosol; TAS:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
309	B7ZRJ4	575	COE2A_XENLA Transcription factor coe2-A OS=Xe...	72	0.027	42	38	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
310	Q810B6	1169	ANFY1_MOUSE Ankyrin repeat and FYVE domain-co...	101	0.32	38.9	30	50	GO:0010008; C:endosome membrane; IDA:UniProtKB.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006897; P:endocytosis; NAS:UniProtKB.
311	Q66H07	344	FANK1_RAT Fibronectin type 3 and ankyrin repe...	124	8.2	33.9	27	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
312	Q9HAK2	575	COE2_HUMAN Transcription factor COE2 OS=Homo ...	72	0.029	42	38	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
313	Q08DL5	575	COE2_BOVIN Transcription factor COE2 OS=Bos t...	72	0.029	42	38	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
314	Q9Y566	2161	SHAN1_HUMAN SH3 and multiple ankyrin repeat d...	87	0.029	42.4	31	48	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; ISS:BHF-UCL.::GO:0005886; C:plasma membrane; ISS:BHF-UCL.::GO:0014069; C:postsynaptic density; ISS:BHF-UCL.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:BHF-UCL.
									GO:0071532; F:ankyrin repeat binding; ISS:BHF-UCL.::GO:0030160; F:GKAP/Homer scaffold activity; ISS:BHF-UCL.::GO:0042802; F:identical protein binding; ISS:BHF-UCL.::GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; ISS:BHF-UCL.
									GO:0008306; P:associative learning; ISS:BHF-UCL.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; NAS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.::GO:0007616; P:long-term memory; ISS:BHF-UCL.::GO:0050885; P:neuromuscular process controlling balance; ISS:BHF-UCL.::GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.::GO:0006461; P:protein complex assembly; ISS:BHF-UCL.::GO:0035418; P:protein localization to synapse; ISS:BHF-UCL.::GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.
315	O08792	575	COE2_MOUSE Transcription factor COE2 OS=Mus m...	72	0.029	42	38	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
316	Q07DY4	1663	CTTB2_COLGU Cortactin-binding protein 2 OS=Co...	82	0.029	42.4	32	50
317	Q8BTI7	1076	ANR52_MOUSE Serine/threonine-protein phosphat...	54	6.9	34.7	33	54
318	Q7T163	1672	KDIS_DANRE Kinase D-interacting substrate of ...	68	3	35.8	29	49	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
319	Q5UPG5	421	YL093_MIMIV Putative ankyrin repeat protein L...	98	1.2	36.6	36	50
320	A0M8S4	1663	CTTB2_PAPAN Cortactin-binding protein 2 OS=Pa...	82	0.031	42.4	32	50
321	P97570	751	PA2G6_RAT 85 kDa calcium-independent phosphol...	121	0.032	42	26	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0047499; F:calcium-independent phospholipase A2 activity; IDA:RGD.
									GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
322	Q9EQG6	1762	KDIS_RAT Kinase D-interacting substrate of 22...	89	1.3	37	30	47	GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0019901; F:protein kinase binding; IDA:RGD.::GO:0019887; F:protein kinase regulator activity; IDA:RGD.
323	Q2IBA2	1662	CTTB2_CHLAE Cortactin-binding protein 2 OS=Ch...	82	0.033	42.4	32	50
324	Q13625	1128	ASPP2_HUMAN Apoptosis-stimulating of p53 prot...	75	0.033	42	32	55	GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
325	Q25338	1214	LITD_LATTR Delta-latroinsectotoxin-Lt1a OS=(L...	64	2.9	35.8	30	52	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0072556; C:other organism presynaptic membrane; IEA:UniProtKB-KW.
									GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
326	Q7EZ44	495	XB35_ORYSJ Probable E3 ubiquitin-protein liga...	75	3.5	35.4	33	52
									GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
327	P56721	575	COLL_DROME Transcription factor collier OS=Dr...	72	0.035	42	38	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0045087; P:innate immune response; IMP:FlyBase.::GO:0035289; P:posterior head segmentation; TAS:FlyBase.::GO:0035203; P:regulation of lamellocyte differentiation; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:FlyBase.::GO:0009608; P:response to symbiont; IMP:FlyBase.::GO:0035291; P:specification of segmental identity, intercalary segment; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
328	P97819	752	PA2G6_MOUSE 85 kDa calcium-independent phosph...	56	6.7	34.7	34	50
									GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
329	Q9ULH0	1771	KDIS_HUMAN Kinase D-interacting substrate of ...	72	3	35.8	38	50	GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.
330	Q9BZF9	1416	UACA_HUMAN Uveal autoantigen with coiled-coil...	102	0.035	42	30	44	GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; NAS:UniProtKB.::GO:0005739; C:mitochondrion; IDA:HPA.
331	Q9H2K2	1166	TNKS2_HUMAN Tankyrase-2 OS=Homo sapiens (Huma...	159	0.73	37.7	24	46	GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0000784; C:nuclear chromosome, telomeric region; IC:BHF-UCL.::GO:0005635; C:nuclear envelope; IDA:BHF-UCL.::GO:0000242; C:pericentriolar material; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
									GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.
									GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0032212; P:positive regulation of telomere maintenance via telomerase; IC:BHF-UCL.::GO:0070213; P:protein auto-ADP-ribosylation; IDA:UniProtKB.::GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.

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