UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YIR012W

Length:

431

Number of sequences:

5887

Description:

YIR012W SQT1 SGDID:S000001451, Chr IX from 378486-379781, Genome Release 64-1-1, Verified ORF, "Essential protein involved in a late step of 60S ribosomal subunit assembly or modification; contains multiple WD repeats; interacts with Qsr1p in a two-hybrid assay"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
91	Q8SRB0	334	GBLP_ENCCU Guanine nucleotide-binding protein...	193	0.31	36.6	21	41
92	Q5R664	906	COPB2_PONAB Coatomer subunit beta' OS=Pongo a...	99	0.31	37.4	27	42	GO:0030663; C:COPI coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0030117; C:membrane coat; IEA:InterPro.
									GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
93	O55029	905	COPB2_MOUSE Coatomer subunit beta' OS=Mus mus...	99	0.32	37	27	42
									GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.
94	Q17GR9	337	CIAO1_AEDAE Probable cytosolic iron-sulfur pr...	129	0.32	36.6	21	42
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
95	B7FF08	1182	WDY_DROVI WD repeat-containing protein on Y c...	259	0.33	37.4	20	38
									GO:0005509; F:calcium ion binding; IEA:InterPro.
96	B4P7Q3	335	CIAO1_DROYA Probable cytosolic iron-sulfur pr...	179	0.34	36.6	23	38
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
97	P87314	932	HIR1_SCHPO Protein hir1 OS=Schizosaccharomyce...	215	0.35	37	22	37	GO:0005829; C:cytosol; IDA:PomBase.::GO:0000417; C:HIR complex; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
									GO:0003682; F:chromatin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003714; F:transcription corepressor activity; TAS:PomBase.
									GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0006336; P:DNA replication-independent nucleosome assembly; TAS:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
98	O13615	473	PRP46_SCHPO Pre-mRNA-splicing factor prp5 OS=...	123	0.35	37	24	43	GO:0005681; C:spliceosomal complex; IDA:PomBase.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IMP:PomBase.
99	Q9UT57	608	CFD1_SCHPO Probable cytosolic Fe-S cluster as...	183	1.9	34.7	22	39	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
									GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; ISS:PomBase.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0016226; P:iron-sulfur cluster assembly; ISS:PomBase.
100	Q5R8K2	431	CSTF1_PONAB Cleavage stimulation factor subun...	215	0.42	36.6	21	39	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
101	Q922V4	513	PLRG1_MOUSE Pleiotropic regulator 1 OS=Mus mu...	193	0.44	36.6	22	40	GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
102	Q4R4I8	906	COPB2_MACFA Coatomer subunit beta' OS=Macaca ...	99	0.45	36.6	27	42	GO:0030663; C:COPI coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0030117; C:membrane coat; IEA:InterPro.
									GO:0005488; F:binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
103	Q6BU94	417	PRP46_DEBHA Pre-mRNA-splicing factor PRP46 OS...	119	0.46	36.2	22	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
104	O35142	905	COPB2_RAT Coatomer subunit beta' OS=Rattus no...	99	0.46	36.6	27	42	GO:0030663; C:COPI coated vesicle membrane; IEA:UniProtKB-SubCell.::GO:0030117; C:membrane coat; IEA:InterPro.
									GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0005198; F:structural molecule activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
105	O75529	589	TAF5L_HUMAN TAF5-like RNA polymerase II p300/...	70	1.1	35.4	29	44	GO:0030914; C:STAGA complex; IDA:UniProtKB.::GO:0033276; C:transcription factor TFTC complex; IDA:UniProtKB.
									GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
									GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
106	B3MC74	335	CIAO1_DROAN Probable cytosolic iron-sulfur pr...	179	0.48	36.2	23	41
									GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
107	Q05048	431	CSTF1_HUMAN Cleavage stimulation factor subun...	215	0.48	36.2	21	39	GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; TAS:ProtInc.
									GO:0006379; P:mRNA cleavage; TAS:ProtInc.::GO:0006378; P:mRNA polyadenylation; TAS:ProtInc.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:Reactome.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
108	O88485	628	DC1I1_MOUSE Cytoplasmic dynein 1 intermediate...	295	0.52	36.6	22	34	GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005868; C:cytoplasmic dynein complex; ISS:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; ISS:HGNC.::GO:0000922; C:spindle pole; ISS:UniProtKB.::GO:0031982; C:vesicle; ISS:UniProtKB.
									GO:0008017; F:microtubule binding; ISS:HGNC.::GO:0003777; F:microtubule motor activity; ISS:HGNC.
									GO:0047496; P:vesicle transport along microtubule; ISS:HGNC.
109	Q15542	800	TAF5_HUMAN Transcription initiation factor TF...	82	8.8	32.3	26	41	GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005669; C:transcription factor TFIID complex; IDA:UniProtKB.::GO:0033276; C:transcription factor TFTC complex; IDA:UniProtKB.
									GO:0046983; F:protein dimerization activity; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
									GO:0016573; P:histone acetylation; IDA:GOC.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.
110	B7FF06	1171	WDY_DROGR WD repeat-containing protein on Y c...	258	0.54	36.6	20	37
									GO:0005509; F:calcium ion binding; IEA:InterPro.
111	Q6P1V3	422	WSB1_XENTR WD repeat and SOCS box-containing ...	86	0.55	36.2	24	41
									GO:0035556; P:intracellular signal transduction; IEA:InterPro.
112	Q1LV15	415	WDR69_DANRE Outer row dynein assembly protein...	69	0.57	36.2	33	42	GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
									GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.::GO:0060285; P:ciliary cell motility; IMP:UniProtKB.::GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.::GO:0007368; P:determination of left/right symmetry; IMP:UniProtKB.
113	Q9WUC8	514	PLRG1_RAT Pleiotropic regulator 1 OS=Rattus n...	193	0.61	36.2	21	40	GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
114	Q4V837	710	DTLA_XENLA Denticleless protein homolog A OS=...	195	0.61	36.2	24	42	GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0031464; C:Cul4A-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0031465; C:Cul4B-RING ubiquitin ligase complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0019985; P:translesion synthesis; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
115	Q9Y2I8	494	WDR37_HUMAN WD repeat-containing protein 37 O...	280	0.63	36.2	20	36
116	Q54J37	827	STRN_DICDI Striatin homolog OS=Dictyostelium ...	319	0.67	36.2	21	38	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
117	A1L112	384	WDR55_RAT WD repeat-containing protein 55 OS=...	159	0.72	35.8	25	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; ISS:UniProtKB.
									GO:0006364; P:rRNA processing; ISS:UniProtKB.
118	Q55FR9	1221	COPA_DICDI Coatomer subunit alpha OS=Dictyost...	70	0.72	36.2	30	46	GO:0030126; C:COPI vesicle coat; IEA:InterPro.
									GO:0005198; F:structural molecule activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.
119	P53622	1201	COPA_YEAST Coatomer subunit alpha OS=Saccharo...	200	0.74	36.2	22	36	GO:0030126; C:COPI vesicle coat; IMP:SGD.
									GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IDA:SGD.
									GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:SGD.
120	Q10051	492	PRP19_CAEEL Pre-mRNA-processing factor 19 hom...	165	0.8	35.8	23	42	GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
									GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
121	Q54Y96	530	SMU1_DICDI WD40 repeat-containing protein smu...	39	0.81	35.8	41	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.

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