UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YIR006C

Length:

1480

Number of sequences:

5887

Description:

YIR006C PAN1 SGDID:S000001445, Chr IX from 369908-365466, Genome Release 64-1-1, reverse complement, Verified ORF, "Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with actin patches on the cell cortex; promotes protein-protein interactions essential for endocytosis; previously thought to be a subunit of poly(A) ribonuclease"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
91	Q8BH64	543	EHD2_MOUSE EH domain-containing protein 2 OS=...	51	0.00002	52.4	43	61	GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0019904; F:protein domain specific binding; IDA:MGI.
									GO:0030866; P:cortical actin cytoskeleton organization; IDA:MGI.::GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0006897; P:endocytosis; IDA:MGI.
92	Q4V8H8	543	EHD2_RAT EH domain-containing protein 2 OS=Ra...	51	0.00002	52.4	43	61	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0032456; P:endocytic recycling; ISS:UniProtKB.
93	A5DF78	379	END3_PICGU Actin cytoskeleton-regulatory comp...	89	0.00002	52.4	33	55	GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
94	Q5BH85	552	IRS4_EMENI Increased rDNA silencing protein 4...	52	0.005	45.1	42	52
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
95	Q6BRH9	765	IRS4_DEBHA Increased rDNA silencing protein 4...	58	0.0002	49.7	40	55
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
96	A5DZL0	882	IRS4_LODEL Increased rDNA silencing protein 4...	68	0.00003	52.4	40	51
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
97	A1DDY6	513	IRS4_NEOFI Increased rDNA silencing protein 4...	65	0.0003	48.9	38	51
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
98	O14066	1379	IRS4_SCHPO Increased rDNA silencing protein 4...	72	0.004	45.8	32	53	GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005739; C:mitochondrion; ISS:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
99	Q4WVH0	513	IRS4_ASPFU Increased rDNA silencing protein 4...	57	0.00003	52	40	61
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
100	Q6C370	400	END3_YARLI Actin cytoskeleton-regulatory comp...	53	0.003	45.4	40	53	GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
101	Q4JQX9	2763	DEN_VZVO Deneddylase ORF22 OS=3). GN=ORF22 ...	46	0.00008	51.2	59	70	GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.::GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.::GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
									GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.
									GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
102	A5DBE7	667	IRS4_PICGU Increased rDNA silencing protein 4...	88	0.003	45.8	32	45
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
103	A1CBF3	501	IRS4_ASPCL Increased rDNA silencing protein 4...	73	0.001	46.6	34	49
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
104	Q2H9M1	741	IRS4_CHAGB Increased rDNA silencing protein 4...	69	0.0008	47.8	30	57
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
105	Q6INA9	1269	SETB1_XENLA Histone-lysine N-methyltransferas...	49	0.0004	48.9	41	61	GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
106	Q6FJW0	870	IRS4_CANGA Increased rDNA silencing protein 4...	79	0.0007	47.8	33	54
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
107	Q6C449	1005	IRS4_YARLI Increased rDNA silencing protein 4...	69	0.0008	47.8	35	54
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
108	Q1DKE6	617	IRS4_COCIM Increased rDNA silencing protein 4...	51	0.003	45.8	41	55
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
109	Q754G7	744	IRS4_ASHGO Increased rDNA silencing protein 4...	85	0.001	47	29	51
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
110	Q755V2	372	END3_ASHGO Actin cytoskeleton-regulatory comp...	53	0.28	38.9	38	47	GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
111	P36115	615	IRS4_YEAST Increased rDNA silencing protein 4...	69	0.031	42.4	30	54	GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000407; C:pre-autophagosomal structure; IDA:SGD.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006914; P:autophagy; IGI:SGD.::GO:0009267; P:cellular response to starvation; IGI:SGD.::GO:0000183; P:chromatin silencing at rDNA; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IGI:SGD.::GO:0048017; P:inositol lipid-mediated signaling; IGI:SGD.::GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
112	A6ZZY3	615	IRS4_YEAS7 Increased rDNA silencing protein 4...	69	0.033	42.4	30	54
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
113	Q6CSC2	638	IRS4_KLULA Increased rDNA silencing protein 4...	79	0.006	44.7	32	53
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
114	A6ZPP1	604	TAX4_YEAS7 Protein TAX4 OS=Saccharomyces cere...	62	0.007	44.7	35	56
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
115	P47030	604	TAX4_YEAST Protein TAX4 OS=Saccharomyces cere...	62	0.007	44.7	35	56	GO:0000407; C:pre-autophagosomal structure; IDA:SGD.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006914; P:autophagy; IGI:SGD.::GO:0009267; P:cellular response to starvation; IGI:SGD.::GO:0031505; P:fungal-type cell wall organization; IGI:SGD.::GO:0048017; P:inositol lipid-mediated signaling; IGI:SGD.::GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
116	Q8XJL8	685	PKN2_CLOPE Probable serine/threonine-protein ...	38	0.32	39.3	55	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
117	Q9VT65	925	CANB_DROME Calpain-B OS=Drosophila melanogast...	112	0.049	42	34	42	GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IDA:UniProtKB.
									GO:0016540; P:protein autoprocessing; TAS:FlyBase.::GO:0006508; P:proteolysis; IDA:UniProtKB.
118	P06707	150	TNNC1_PONLE Troponin C, isotype alpha OS=lept...	68	0.078	38.9	31	56
									GO:0005509; F:calcium ion binding; IEA:InterPro.
119	Q63ZJ3	271	SEGN_XENLA Secretagogin OS=Xenopus laevis (Af...	88	0.096	40	35	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005509; F:calcium ion binding; IEA:InterPro.
120	Q0VFG3	271	SEGN_XENTR Secretagogin OS=Xenopus tropicalis...	88	0.12	40	35	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005509; F:calcium ion binding; IEA:InterPro.
121	Q09665	160	TNNC2_CAEEL Troponin C, isoform 2 OS=Caenorha...	68	0.2	38.1	29	51
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0031013; F:troponin I binding; IPI:WormBase.
									GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.

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