UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YIR005W

Length:

148

Number of sequences:

5887

Description:

YIR005W IST3 SGDID:S000001444, Chr IX from 364889-365335, Genome Release 64-1-1, Verified ORF, "Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
631	Q00916	300	RU17_YEAST U1 small nuclear ribonucleoprotein...	112	0.1	35.4	26	54	GO:0000243; C:commitment complex; IPI:SGD.::GO:0005685; C:U1 snRNP; IDA:SGD.::GO:0071004; C:U2-type prespliceosome; IDA:SGD.
									GO:0003729; F:mRNA binding; IPI:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0030619; F:U1 snRNA binding; IPI:SGD.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; IPI:SGD.
632	Q5RFL9	471	NONO_PONAB Non-POU domain-containing octamer-...	100	0.1	35.8	20	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
633	Q15233	471	NONO_HUMAN Non-POU domain-containing octamer-...	100	0.1	35.8	20	50	GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0042382; C:paraspeckles; IDA:MGI.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
634	Q99K48	473	NONO_MOUSE Non-POU domain-containing octamer-...	100	0.1	35.8	20	50
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
635	O43390	633	HNRPR_HUMAN Heterogeneous nuclear ribonucleop...	62	6.8	30.4	26	55	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030530; C:heterogeneous nuclear ribonucleoprotein complex; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; TAS:ProtInc.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.
636	Q6TY21	218	EPA2B_XENLA Embryonic polyadenylate-binding p...	99	0.11	35.4	27	48	GO:0005737; C:cytoplasm; IDA:UniProtKB.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; IDA:UniProtKB.
637	Q8TBY0	533	RBM46_HUMAN Probable RNA-binding protein 46 O...	83	0.95	32.7	31	58
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
638	Q5FVM4	476	NONO_RAT Non-POU domain-containing octamer-bi...	100	0.11	35.4	20	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
639	Q7XTT4	707	NUCL2_ORYSJ Nucleolin 2 OS=Oryza sativa subsp...	84	4.7	30.8	25	51
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
640	P86049	533	RBM46_MOUSE Probable RNA-binding protein 46 O...	83	1	32.7	31	58
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
641	Q76FK4	1167	NOL8_HUMAN Nucleolar protein 8 OS=Homo sapien...	52	0.12	35.8	33	63	GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:UniProtKB.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006260; P:DNA replication; IMP:HGNC.::GO:0030307; P:positive regulation of cell growth; IMP:HGNC.::GO:0006364; P:rRNA processing; IMP:UniProtKB.
642	Q177H0	159	NCBP2_AEDAE Nuclear cap-binding protein subun...	73	0.12	35	27	52	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
643	Q6Z1C0	572	NUCL1_ORYSJ Nucleolin 1 OS=Oryza sativa subsp...	73	0.48	33.9	36	53
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
644	Q8VE97	489	SRSF4_MOUSE Serine/arginine-rich splicing fac...	75	0.12	35.4	28	49	GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
645	Q8R3C6	952	RBM19_MOUSE Probable RNA-binding protein 19 O...	105	0.85	33.1	23	48	GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0040019; P:positive regulation of embryonic development; IMP:UniProtKB.
646	Q3T0I4	257	THOC4_BOVIN THO complex subunit 4 OS=Bos taur...	91	0.12	35	25	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
647	Q08170	494	SRSF4_HUMAN Serine/arginine-rich splicing fac...	75	0.13	35.4	28	49	GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.::GO:0006406; P:mRNA export from nucleus; TAS:Reactome.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:Reactome.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
648	Q86V81	257	THOC4_HUMAN THO complex subunit 4 OS=Homo sap...	72	0.13	35	26	51	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000346; C:transcription export complex; IDA:UniProtKB.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0046784; P:intronless viral mRNA export from host nucleus; IDA:UniProtKB.::GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
649	Q4R2Z0	485	RBM46_MACFA Probable RNA-binding protein 46 O...	81	1.2	32.3	25	53
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
650	A5DNX9	274	EIF3G_PICGU Eukaryotic translation initiation...	35	0.14	35	43	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
651	B3P0D7	154	NCBP2_DROER Nuclear cap-binding protein subun...	129	0.16	34.7	22	44	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
652	C1BY64	155	NCBP2_ESOLU Nuclear cap-binding protein subun...	73	0.16	34.7	26	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0046833; P:positive regulation of RNA export from nucleus; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0006408; P:snRNA export from nucleus; ISS:UniProtKB.
653	B5G279	168	NCBP2_TAEGU Nuclear cap-binding protein subun...	78	0.16	34.7	26	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
654	Q5YD48	595	A1CF_MOUSE APOBEC1 complementation factor OS=...	73	0.16	35	29	59	GO:0030895; C:apolipoprotein B mRNA editing enzyme complex; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.
									GO:0016554; P:cytidine to uridine editing; TAS:HGNC.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0050821; P:protein stabilization; ISS:UniProtKB.
655	C0H859	155	NCBP2_SALSA Nuclear cap-binding protein subun...	73	0.17	34.7	26	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0046833; P:positive regulation of RNA export from nucleus; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0006408; P:snRNA export from nucleus; ISS:UniProtKB.
656	Q1PEP5	636	NUCL2_ARATH Nucleolin 2 OS=Arabidopsis thalia...	86	5.1	30.8	31	49
									GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
657	A2SW84	165	NCBP2_SINCH Nuclear cap-binding protein subun...	78	0.17	34.7	26	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0046833; P:positive regulation of RNA export from nucleus; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0006408; P:snRNA export from nucleus; ISS:UniProtKB.
658	P20397	651	NUCL_XENLA Nucleolin OS=Xenopus laevis (Afric...	79	0.17	35	24	53	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
659	O01159	452	RSP7_CAEEL Probable splicing factor, arginine...	77	0.18	35	29	57	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
660	O42923	490	CIP1_SCHPO RNA-binding post-transcriptional r...	95	0.18	35	23	45	GO:0005829; C:cytosol; IDA:PomBase.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0034599; P:cellular response to oxidative stress; IGI:PomBase.::GO:2000815; P:regulation of mRNA stability involved in response to oxidative stress; IMP:PomBase.
661	Q1HE01	154	NCBP2_BOMMO Nuclear cap-binding protein subun...	78	0.18	34.3	26	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.

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