Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIR005W
Length:
148
Number of sequences:
5887
Description:
YIR005W IST3 SGDID:S000001444, Chr IX from 364889-365335, Genome Release 64-1-1, Verified ORF, "Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
601P36629    517   U2AF2_SCHPO Splicing factor U2AF 59 kDa subun...620.72     33.1     26     52GO:0000243; C:commitment complex; IDA:PomBase.::GO:0005686; C:U2 snRNP; TAS:PomBase.
GO:0003729; F:mRNA binding; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0030515; F:snoRNA binding; TAS:PomBase.
GO:0000349; P:generation of catalytic spliceosome for first transesterification step; IDA:PomBase.::GO:0000348; P:nuclear mRNA branch site recognition; ISS:PomBase.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; IMP:PomBase.
602Q5XFR0    273   EPAB2_MOUSE Embryonic polyadenylate-binding p...760.053     36.2     26     53GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; ISS:UniProtKB.
603Q26548    273   PPIE_SCHMA Peptidyl-prolyl cis-trans isomeras...870.054     36.2     26     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0042277; F:peptide binding; IEA:UniProtKB-KW.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
604Q9D0B0    222   SRSF9_MOUSE Serine/arginine-rich splicing fac...730.055     36.2     30     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
605Q6DES0    153   NCBP2_XENTR Nuclear cap-binding protein subun...780.057     35.8     26     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0046833; P:positive regulation of RNA export from nucleus; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0006408; P:snRNA export from nucleus; ISS:UniProtKB.
606Q8CGC6    750   RBM28_MOUSE RNA-binding protein 28 OS=Mus mus...980.061     36.6     27     54GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
607B0BNE4    269   EPAB2_RAT Embryonic polyadenylate-binding pro...900.061     36.2     24     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
608Q9Y4C8    960   RBM19_HUMAN Probable RNA-binding protein 19 O...761.5     32.3     25     50GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0040019; P:positive regulation of embryonic development; ISS:UniProtKB.
609Q22037    346   ROA1_CAEEL Heterogeneous nuclear ribonucleopr...470.062     36.2     30     57GO:0000781; C:chromosome, telomeric region; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0031581; P:hemidesmosome assembly; IGI:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.
610O94359    116   YHOC_SCHPO Uncharacterized RNA-binding protei...740.063     35     23     54GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
611Q08473    344   SQD_DROME RNA-binding protein squid OS=Drosop...510.069     36.2     31     59GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.::GO:0000785; C:chromatin; IDA:FlyBase.::GO:0005737; C:cytoplasm; TAS:FlyBase.::GO:0035062; C:omega speckle; IDA:FlyBase.::GO:0005703; C:polytene chromosome puff; IDA:FlyBase.::GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.
GO:0003730; F:mRNA 3'-UTR binding; TAS:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0008069; P:dorsal/ventral axis specification, ovarian follicular epithelium; IMP:FlyBase.::GO:0006406; P:mRNA export from nucleus; NAS:FlyBase.::GO:0033119; P:negative regulation of RNA splicing; IMP:FlyBase.::GO:0017148; P:negative regulation of translation; TAS:FlyBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:FlyBase.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:FlyBase.::GO:0030720; P:oocyte localization involved in germarium-derived egg chamber formation; IMP:FlyBase.::GO:0016325; P:oocyte microtubule cytoskeleton organization; IMP:FlyBase.::GO:0007297; P:ovarian follicle cell migration; IMP:FlyBase.::GO:0045451; P:pole plasm oskar mRNA localization; IEP:FlyBase.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IMP:FlyBase.
612Q13151    305   ROA0_HUMAN Heterogeneous nuclear ribonucleopr...500.063     36.2     24     62GO:0030530; C:heterogeneous nuclear ribonucleoprotein complex; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0017091; F:AU-rich element binding; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; ISS:UniProtKB.::GO:0006954; P:inflammatory response; ISS:UniProtKB.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:Reactome.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.
613Q5XI28    748   RAVR1_RAT Ribonucleoprotein PTB-binding 1 OS=...1080.063     36.2     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
614Q9CW46    748   RAVR1_MOUSE Ribonucleoprotein PTB-binding 1 O...1080.063     36.2     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
615Q5PPI1    221   SRSF9_RAT Serine/arginine-rich splicing facto...730.066     35.8     30     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
616Q8IY67    606   RAVR1_HUMAN Ribonucleoprotein PTB-binding 1 O...1080.067     36.2     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
617Q62504    3644   MINT_MOUSE Msx2-interacting protein OS=Mus mu...1034.2     31.2     22     42GO:0005634; C:nucleus; IDA:MGI.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0003697; F:single-stranded DNA binding; IDA:MGI.::GO:0003714; F:transcription corepressor activity; IDA:MGI.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
618Q9CX86    305   ROA0_MOUSE Heterogeneous nuclear ribonucleopr...690.068     36.2     19     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0017091; F:AU-rich element binding; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:UniProtKB.::GO:0006954; P:inflammatory response; IDA:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; IDA:UniProtKB.
619Q8JGR6    155   NCBP2_DANRE Nuclear cap-binding protein subun...780.069     35.4     26     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0046833; P:positive regulation of RNA export from nucleus; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0006408; P:snRNA export from nucleus; ISS:UniProtKB.
620P52299    153   NCBP2_XENLA Nuclear cap-binding protein subun...780.072     35.4     26     53GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005845; C:mRNA cap binding complex; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0000340; F:RNA 7-methylguanosine cap binding; ISS:UniProtKB.
GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006370; P:mRNA capping; ISS:UniProtKB.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; ISS:UniProtKB.::GO:0046833; P:positive regulation of RNA export from nucleus; IDA:UniProtKB.::GO:0006446; P:regulation of translational initiation; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IDA:UniProtKB.::GO:0006408; P:snRNA export from nucleus; IDA:UniProtKB.
621P92966    356   RSP41_ARATH Arginine/serine-rich-splicing fac...770.075     35.8     29     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0008380; P:RNA splicing; NAS:TAIR.
622Q96T37    977   RBM15_HUMAN Putative RNA-binding protein 15 O...600.083     36.2     28     60GO:0005634; C:nucleus; IDA:HPA.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
623Q27294    399   CAZ_DROME RNA-binding protein cabeza OS=Droso...800.085     35.8     26     49GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008344; P:adult locomotory behavior; IMP:FlyBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:FlyBase.
624Q9CPN8    579   IF2B3_MOUSE Insulin-like growth factor 2 mRNA...830.095     35.8     27     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
625O08583    255   THOC4_MOUSE THO complex subunit 4 OS=Mus musc...910.095     35.4     25     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0003697; F:single-stranded DNA binding; IDA:MGI.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
626Q54J05    241   RU2B_DICDI U2 small nuclear ribonucleoprotein...970.096     35.4     28     55GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0017069; F:snRNA binding; IEA:InterPro.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IEA:InterPro.
627P32831    672   NGR1_YEAST Negative growth regulatory protein...940.35     34.3     23     50GO:0000932; C:cytoplasmic mRNA processing body; IDA:SGD.::GO:0010494; C:cytoplasmic stress granule; IDA:SGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:SGD.
GO:0003729; F:mRNA binding; IDA:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0061158; P:3'-UTR-mediated mRNA destabilization; IDA:SGD.::GO:0007005; P:mitochondrion organization; IMP:SGD.
628Q7ZXB8    295   PAB2B_XENLA Polyadenylate-binding protein 2-B...640.098     35.4     34     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; ISS:UniProtKB.
GO:0006378; P:mRNA polyadenylation; ISS:UniProtKB.
629Q96T58    3664   MINT_HUMAN Msx2-interacting protein OS=Homo s...720.1     35.8     28     53GO:0017053; C:transcriptional repressor complex; IDA:BHF-UCL.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0050769; P:positive regulation of neurogenesis; IMP:BHF-UCL.
630Q6NVP7    296   PABP2_XENTR Polyadenylate-binding protein 2 O...780.1     35.4     33     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; ISS:UniProtKB.
GO:0006378; P:mRNA polyadenylation; ISS:UniProtKB.
631Q00916    300   RU17_YEAST U1 small nuclear ribonucleoprotein...1120.1     35.4     26     54GO:0000243; C:commitment complex; IPI:SGD.::GO:0005685; C:U1 snRNP; IDA:SGD.::GO:0071004; C:U2-type prespliceosome; IDA:SGD.
GO:0003729; F:mRNA binding; IPI:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0030619; F:U1 snRNA binding; IPI:SGD.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IPI:SGD.
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