Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIR005W
Length:
148
Number of sequences:
5887
Description:
YIR005W IST3 SGDID:S000001444, Chr IX from 364889-365335, Genome Release 64-1-1, Verified ORF, "Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
421Q96DU9    382   PABP5_HUMAN Polyadenylate-binding protein 5 O...754.5     30.8     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
422P60047    382   PABP5_GORGO Polyadenylate-binding protein 5 O...754.5     30.8     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
423P26369    475   U2AF2_MOUSE Splicing factor U2AF 65 kDa subun...770.002     40.4     30     55GO:0016607; C:nuclear speck; TAS:UniProtKB.
GO:0070742; F:C2H2 zinc finger domain binding; IPI:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IDA:UniProtKB.
424P26368    475   U2AF2_HUMAN Splicing factor U2AF 65 kDa subun...770.002     40.4     30     55GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005681; C:spliceosomal complex; IDA:HGNC.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.::GO:0006406; P:mRNA export from nucleus; TAS:Reactome.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:HGNC.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
425Q9Y6M1    599   IF2B2_HUMAN Insulin-like growth factor 2 mRNA...850.002     40.4     28     56GO:0044430; C:cytoskeletal part; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.::GO:0048027; F:mRNA 5'-UTR binding; IDA:BHF-UCL.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0045182; F:translation regulator activity; ISS:BHF-UCL.
GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.::GO:0017148; P:negative regulation of translation; ISS:BHF-UCL.::GO:0042035; P:regulation of cytokine biosynthetic process; IC:BHF-UCL.
426Q5M9F1    428   RBM34_RAT RNA-binding protein 34 OS=Rattus no...980.002     40.4     28     52GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
427Q5SF07    592   IF2B2_MOUSE Insulin-like growth factor 2 mRNA...850.003     40.4     28     56GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0044430; C:cytoskeletal part; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0048027; F:mRNA 5'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
428O22315    303   SRSF1_ARATH Pre-mRNA-splicing factor SF2 OS=A...730.003     40     26     56GO:0035061; C:interchromatin granule; IDA:TAIR.::GO:0016607; C:nuclear speck; IDA:TAIR.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
429O57526    593   IF23B_XENLA Insulin-like growth factor 2 mRNA...860.003     40.4     26     56GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
430O14327    166   PAB2_SCHPO Polyadenylate-binding protein 2 OS...890.003     39.7     29     52GO:0005634; C:nucleus; IDA:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; IDA:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IMP:PomBase.
431Q9JKL7    494   SREK1_RAT Splicing regulatory glutamine/lysin...1110.003     40     30     50GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
432O73932    594   IF23A_XENLA Insulin-like growth factor 2 mRNA...860.003     40     26     56GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IPI:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
433Q1JPH6    228   IF4H_BOVIN Eukaryotic translation initiation ...720.003     40     32     60GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
434Q8BZX4    494   SREK1_MOUSE Splicing regulatory glutamine/lys...1110.003     40     30     50GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
435Q6CQR6    878   MRD1_KLULA Multiple RNA-binding domain-contai...980.68     33.5     24     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
436A5E1Z4    279   EIF3G_LODEL Eukaryotic translation initiation...680.003     40     35     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
437Q6DCB7    371   DND1_XENLA Dead end protein homolog 1 OS=Xeno...960.003     40     28     51GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0017091; F:AU-rich element binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0060965; P:negative regulation of gene silencing by miRNA; ISS:UniProtKB.
438O14979    420   HNRDL_HUMAN Heterogeneous nuclear ribonucleop...830.37     33.9     22     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030530; C:heterogeneous nuclear ribonucleoprotein complex; TAS:ProtInc.
GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; TAS:ProtInc.::GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
439Q5RBR8    228   IF4H_PONAB Eukaryotic translation initiation ...720.003     39.7     32     60GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
440P23246    707   SFPQ_HUMAN Splicing factor, proline- and glut...1070.003     40     23     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0042382; C:paraspeckles; IDA:BHF-UCL.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000380; P:alternative nuclear mRNA splicing, via spliceosome; IMP:BHF-UCL.::GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
441Q8IUH3    476   RBM45_HUMAN RNA-binding protein 45 OS=Homo sa...810.004     39.7     30     49GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IDA:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; ISS:UniProtKB.
442Q5RB68    556   IF2B2_PONAB Insulin-like growth factor 2 mRNA...850.004     39.7     28     56GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0044430; C:cytoskeletal part; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0048027; F:mRNA 5'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
443Q62376    448   RU17_MOUSE U1 small nuclear ribonucleoprotein...1010.004     39.7     25     50GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; ISS:UniProtKB.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0043484; P:regulation of RNA splicing; ISS:UniProtKB.
444Q5NVM8    305   RNPS1_PONAB RNA-binding protein with serine-r...760.004     39.7     28     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
445Q99M28    305   RNPS1_MOUSE RNA-binding protein with serine-r...760.004     39.7     28     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
446Q4R5N1    305   RNPS1_MACFA RNA-binding protein with serine-r...760.004     39.7     28     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
447Q15287    305   RNPS1_HUMAN RNA-binding protein with serine-r...760.004     39.7     28     58GO:0005829; C:cytosol; TAS:Reactome.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.::GO:0006406; P:mRNA export from nucleus; TAS:Reactome.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:Reactome.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
448A6QR16    305   RNPS1_BOVIN RNA-binding protein with serine-r...760.004     39.7     28     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
449Q9UT83    609   MUG28_SCHPO Meiotically up-regulated gene 28 ...647.6     30.4     23     50GO:0005619; C:ascospore wall; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005628; C:prospore membrane; IDA:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0031321; P:ascospore-type prospore assembly; IMP:PomBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
450Q6AYK1    305   RNPS1_RAT RNA-binding protein with serine-ric...760.004     39.7     28     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
451Q8VIJ6    699   SFPQ_MOUSE Splicing factor, proline- and glut...1070.004     39.7     23     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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