Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIR005W
Length:
148
Number of sequences:
5887
Description:
YIR005W IST3 SGDID:S000001444, Chr IX from 364889-365335, Genome Release 64-1-1, Verified ORF, "Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361Q6CEW9    828   MRD1_YARLI Multiple RNA-binding domain-contai...730.11     35.8     32     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
362P48809    421   RB27C_DROME Heterogeneous nuclear ribonucleop...490.075     36.2     24     61GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005654; C:nucleoplasm; IDA:FlyBase.::GO:0043234; C:protein complex; IPI:FlyBase.::GO:0030529; C:ribonucleoprotein complex; IDA:FlyBase.
GO:0003730; F:mRNA 3'-UTR binding; IDA:FlyBase.::GO:0048027; F:mRNA 5'-UTR binding; NAS:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:FlyBase.::GO:0003697; F:single-stranded DNA binding; IDA:FlyBase.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0007319; P:negative regulation of oskar mRNA translation; TAS:FlyBase.::GO:0045451; P:pole plasm oskar mRNA localization; IMP:FlyBase.::GO:0045727; P:positive regulation of translation; IDA:FlyBase.::GO:0048024; P:regulation of nuclear mRNA splicing, via spliceosome; IMP:FlyBase.
363Q05196    682   PABP5_ARATH Polyadenylate-binding protein 5 O...1040.11     35.8     25     49GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; IDA:TAIR.
GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IGI:TAIR.::GO:0006413; P:translational initiation; IGI:TAIR.
364O81126    200   RZP22_ARATH Serine/arginine-rich splicing fac...680.0005     42     32     56GO:0016607; C:nuclear speck; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:TAIR.
365Q871A4    494   PPIL4_NEUCR Peptidyl-prolyl cis-trans isomera...750.0005     42.4     27     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006457; P:protein folding; IEA:UniProtKB-KW.
366Q9UNP9    301   PPIE_HUMAN Peptidyl-prolyl cis-trans isomeras...810.0005     42.4     26     54GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.
GO:0016018; F:cyclosporin A binding; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; TAS:UniProtKB.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:UniProtKB.
367O01671    321   SXL_MEGSC Sex-lethal homolog OS=Megaselia sca...750.046     36.6     25     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
368A4FV72    301   PPIE_BOVIN Peptidyl-prolyl cis-trans isomeras...810.0005     42     26     54GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
369Q9QZH3    301   PPIE_MOUSE Peptidyl-prolyl cis-trans isomeras...810.0006     42     26     54GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
370Q5R723    301   PPIE_PONAB Peptidyl-prolyl cis-trans isomeras...810.0006     42     26     54GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
371A5DM21    631   PABP_PICGU Polyadenylate-binding protein, cyt...720.0008     42     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
372Q9ZQA8    609   PABPX_ARATH Probable polyadenylate-binding pr...840.11     35.8     29     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
373F4I3B3    445   RB47A_ARATH Polyadenylate-binding protein RBP...830.066     36.2     24     52GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; ISS:UniProtKB.
GO:0034605; P:cellular response to heat; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
374P27476    414   NSR1_YEAST Nuclear localization sequence-bind...860.18     35     22     49GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005730; C:nucleolus; TAS:SGD.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IDA:SGD.::GO:0003697; F:single-stranded DNA binding; IDA:SGD.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0000028; P:ribosomal small subunit assembly; TAS:SGD.::GO:0006364; P:rRNA processing; TAS:SGD.
375P16914    483   ELAV_DROME Protein elav OS=Drosophila melanog...920.17     35     26     49GO:0015030; C:Cajal body; IDA:FlyBase.
GO:0003729; F:mRNA binding; NAS:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008266; F:poly(U) RNA binding; IDA:FlyBase.::GO:0000900; F:translation repressor activity, nucleic acid binding; NAS:UniProtKB.
GO:0007417; P:central nervous system development; IMP:FlyBase.::GO:0009790; P:embryo development; NAS:UniProtKB.::GO:0007281; P:germ cell development; NAS:UniProtKB.::GO:0031441; P:negative regulation of mRNA 3'-end processing; IDA:FlyBase.::GO:0007319; P:negative regulation of oskar mRNA translation; NAS:UniProtKB.
376P23241    519   ELAV_DROVI Protein elav OS=Drosophila virilis...920.18     35     26     49GO:0016592; C:mediator complex; IEA:InterPro.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
377O13829    261   RU17_SCHPO U1 small nuclear ribonucleoprotein...740.0007     41.6     30     58GO:0000243; C:commitment complex; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005685; C:U1 snRNP; IDA:PomBase.
GO:0003729; F:mRNA binding; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0030619; F:U1 snRNA binding; ISS:PomBase.
GO:0000395; P:nuclear mRNA 5'-splice site recognition; ISS:PomBase.
378O14369    388   SCE3_SCHPO Probable RNA-binding protein sce3 ...850.0008     42     32     55GO:0005829; C:cytosol; IDA:PomBase.::GO:0005840; C:ribosome; ISS:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; ISS:PomBase.
GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.
379P41891    500   GAR2_SCHPO Protein gar2 OS=Schizosaccharomyce...1021.3     32.3     25     46GO:0005730; C:nucleolus; IDA:PomBase.::GO:0005732; C:small nucleolar ribonucleoprotein complex; ISS:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; TAS:PomBase.
GO:0007000; P:nucleolus organization; IMP:PomBase.::GO:0006364; P:rRNA processing; IMP:PomBase.
380P17133    448   RU17_DROME U1 small nuclear ribonucleoprotein...730.0008     41.6     26     56GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.::GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.::GO:0005685; C:U1 snRNP; ISS:FlyBase.
GO:0003729; F:mRNA binding; IDA:FlyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; IPI:FlyBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IMP:FlyBase.
381Q925G0    155   RBM3_RAT Putative RNA-binding protein 3 OS=Ra...750.0008     40.8     25     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0045727; P:positive regulation of translation; IDA:UniProtKB.
382O59670    115   PM14_SCHPO Pre-mRNA branch site p14-like prot...850.0008     40     31     58GO:0005681; C:spliceosomal complex; NAS:PomBase.::GO:0005686; C:U2 snRNP; ISS:PomBase.
GO:0000384; F:first spliceosomal transesterification activity; ISS:PomBase.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
383P48810    385   RB87F_DROME Heterogeneous nuclear ribonucleop...490.24     34.7     29     63GO:0000785; C:chromatin; IDA:FlyBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0035062; C:omega speckle; IDA:FlyBase.::GO:0005703; C:polytene chromosome puff; IDA:FlyBase.::GO:0030529; C:ribonucleoprotein complex; IDA:FlyBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.
GO:0007067; P:mitosis; IMP:FlyBase.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IMP:FlyBase.
384Q14103    355   HNRPD_HUMAN Heterogeneous nuclear ribonucleop...660.0009     41.6     33     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0030530; C:heterogeneous nuclear ribonucleoprotein complex; NAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IDA:UniProtKB.::GO:0042162; F:telomeric DNA binding; IDA:UniProtKB.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:Reactome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006401; P:RNA catabolic process; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
385Q60668    355   HNRPD_MOUSE Heterogeneous nuclear ribonucleop...660.0009     41.6     33     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; ISS:UniProtKB.::GO:0042162; F:telomeric DNA binding; ISS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
386O81127    187   RZP21_ARATH Serine/arginine-rich splicing fac...680.001     40.8     31     60GO:0016607; C:nuclear speck; IDA:TAIR.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:TAIR.
387Q10355    219   YDB2_SCHPO Uncharacterized RNA-binding protei...800.001     41.2     29     54GO:0005634; C:nucleus; IDA:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0007126; P:meiosis; IEP:PomBase.
388Q43472    161   GRP_HORVU Glycine-rich RNA-binding protein bl...750.001     40.8     24     49
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IDA:UniProtKB.::GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0009737; P:response to abscisic acid stimulus; IDA:UniProtKB.::GO:0009409; P:response to cold; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
389Q66II8    471   RU17_XENTR U1 small nuclear ribonucleoprotein...1010.001     41.6     26     51GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; ISS:UniProtKB.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0043484; P:regulation of RNA splicing; ISS:UniProtKB.
390Q8N6W0    485   CELF5_HUMAN CUGBP Elav-like family member 5 O...600.062     36.2     30     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
391P21522    342   ROA1_SCHAM Heterogeneous nuclear ribonucleopr...490.013     38.1     29     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
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