UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YIR005W

Length:

148

Number of sequences:

5887

Description:

YIR005W IST3 SGDID:S000001444, Chr IX from 364889-365335, Genome Release 64-1-1, Verified ORF, "Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q6GL69	276	MK67I_XENTR MKI67 FHA domain-interacting nucl...	164	0.00000002	55.1	26	45	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
32	P49314	292	ROC2_NICPL 31 kDa ribonucleoprotein, chloropl...	87	0.25	34.3	23	48	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
33	Q08935	273	ROC1_NICSY 29 kDa ribonucleoprotein A, chloro...	74	0.01	38.5	27	49	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
34	Q08937	291	ROC2_NICSY 29 kDa ribonucleoprotein B, chloro...	87	0.076	35.8	24	48	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
35	Q0CR95	753	PABP_ASPTN Polyadenylate-binding protein, cyt...	91	0.66	33.5	22	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
36	Q14498	530	RBM39_HUMAN RNA-binding protein 39 OS=Homo sa...	87	0.52	33.5	28	47	GO:0005813; C:centrosome; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
37	P49313	279	ROC1_NICPL 30 kDa ribonucleoprotein, chloropl...	74	0.017	37.7	27	49	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
38	Q28IQ9	166	CIRBP_XENTR Cold-inducible RNA-binding protei...	79	0.00000004	52.8	30	57	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0019899; F:enzyme binding; ISS:UniProtKB.::GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007369; P:gastrulation; ISS:UniProtKB.::GO:0048255; P:mRNA stabilization; ISS:UniProtKB.::GO:0060212; P:negative regulation of nuclear-transcribed mRNA poly(A) tail shortening; ISS:UniProtKB.::GO:0022008; P:neurogenesis; ISS:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0048793; P:pronephros development; ISS:UniProtKB.::GO:0009409; P:response to cold; ISS:UniProtKB.
39	Q0U6E7	281	EIF3G_PHANO Eukaryotic translation initiation...	77	0.00000004	54.3	31	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
40	Q5RC80	524	RBM39_PONAB RNA-binding protein 39 OS=Pongo a...	87	0.61	33.5	28	47	GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
41	Q8VH51	530	RBM39_MOUSE RNA-binding protein 39 OS=Mus mus...	87	0.61	33.5	28	47	GO:0005634; C:nucleus; TAS:MGI.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; TAS:MGI.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; TAS:MGI.
42	Q3SZM1	296	MK67I_BOVIN MKI67 FHA domain-interacting nucl...	97	0.00000005	53.9	33	51	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
43	A5A6M3	391	RBMX_PANTR RNA-binding motif protein, X chrom...	75	0.00000006	54.3	35	60	GO:0071013; C:catalytic step 2 spliceosome; ISS:UniProtKB.::GO:0070062; C:extracellular vesicular exosome; ISS:UniProtKB.::GO:0005719; C:nuclear euchromatin; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001047; F:core promoter binding; ISS:UniProtKB.::GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0071347; P:cellular response to interleukin-1; ISS:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0048026; P:positive regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
44	P38159	391	RBMX_HUMAN RNA-binding motif protein, X chrom...	75	0.00000006	54.3	35	60	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0070062; C:extracellular vesicular exosome; IDA:UniProtKB.::GO:0030530; C:heterogeneous nuclear ribonucleoprotein complex; NAS:UniProtKB.::GO:0005719; C:nuclear euchromatin; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
									GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0001047; F:core promoter binding; IDA:UniProtKB.::GO:0003729; F:mRNA binding; IDA:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0071347; P:cellular response to interleukin-1; IDA:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.::GO:0048026; P:positive regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
45	Q4R7F0	391	RBMX_MACFA RNA-binding motif protein, X chrom...	75	0.00000006	54.3	35	60	GO:0071013; C:catalytic step 2 spliceosome; ISS:UniProtKB.::GO:0070062; C:extracellular vesicular exosome; ISS:UniProtKB.::GO:0005719; C:nuclear euchromatin; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001047; F:core promoter binding; ISS:UniProtKB.::GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0071347; P:cellular response to interleukin-1; ISS:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0048026; P:positive regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
46	Q4V898	390	RBMX_RAT RNA-binding motif protein, X chromos...	75	0.00000006	53.9	35	60	GO:0005681; C:spliceosomal complex; IDA:RGD.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0003727; F:single-stranded RNA binding; IDA:RGD.
									GO:0006376; P:mRNA splice site selection; IMP:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
47	P52912	386	TIA1_MOUSE Nucleolysin TIA-1 OS=Mus musculus ...	76	0.058	36.2	24	50
48	Q9WV02	391	RBMX_MOUSE RNA-binding motif protein, X chrom...	75	0.00000006	53.9	35	60	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49	A1D4K4	751	PABP_NEOFI Polyadenylate-binding protein, cyt...	91	0.52	33.9	22	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
50	Q4WK03	753	PABP_ASPFU Polyadenylate-binding protein, cyt...	91	0.55	33.5	22	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
51	B0VZS1	272	EIF3G_CULQU Eukaryotic translation initiation...	66	0.0000001	52.8	36	59	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
52	P31483	386	TIA1_HUMAN Nucleolysin TIA-1 isoform p40 OS=H...	76	0.099	35.8	24	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0048024; P:regulation of nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.
53	Q1HQN4	272	EIF3G_AEDAE Eukaryotic translation initiation...	66	0.0000001	52.8	36	59	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
54	Q91VM5	388	RMXL1_MOUSE RNA binding motif protein, X-link...	75	0.0000001	53.1	33	60	GO:0071013; C:catalytic step 2 spliceosome; ISS:UniProtKB.::GO:0070062; C:extracellular vesicular exosome; ISS:UniProtKB.::GO:0005719; C:nuclear euchromatin; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0001047; F:core promoter binding; IDA:UniProtKB.::GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0071347; P:cellular response to interleukin-1; ISS:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0048026; P:positive regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
55	Q7SYS2	278	MK67I_XENLA MKI67 FHA domain-interacting nucl...	81	0.0000001	52.8	32	56	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
56	Q4P8R9	651	PABP_USTMA Polyadenylate-binding protein, cyt...	92	0.005	39.7	26	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
57	Q7S6N6	764	PABP_NEUCR Polyadenylate-binding protein, cyt...	105	0.002	40.4	24	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
58	Q29RT0	396	RBMX_BOVIN RNA-binding motif protein, X chrom...	72	0.0000001	52.8	35	60	GO:0071013; C:catalytic step 2 spliceosome; ISS:UniProtKB.::GO:0070062; C:extracellular vesicular exosome; ISS:UniProtKB.::GO:0005719; C:nuclear euchromatin; ISS:UniProtKB.
									GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001047; F:core promoter binding; ISS:UniProtKB.::GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0071347; P:cellular response to interleukin-1; ISS:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0048026; P:positive regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
59	B4NTY9	269	EI3G1_DROSI Eukaryotic translation initiation...	66	0.0000001	52.4	36	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
60	B4I9X1	269	EI3G1_DROSE Eukaryotic translation initiation...	66	0.0000001	52.4	36	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
61	B4Q0Y7	269	EI3G1_DROYA Eukaryotic translation initiation...	66	0.0000002	52.4	36	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.

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