Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIR005W
Length:
148
Number of sequences:
5887
Description:
YIR005W IST3 SGDID:S000001444, Chr IX from 364889-365335, Genome Release 64-1-1, Verified ORF, "Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q7SZT7    400   ELAV4_XENLA ELAV-like protein 4 OS=Xenopus la...790.002     40.4     28     54GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
302Q9EPH8    636   PABP1_RAT Polyadenylate-binding protein 1 OS=...840.56     33.5     23     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:2000623; P:negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; ISS:UniProtKB.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
303O09032    373   ELAV4_RAT ELAV-like protein 4 OS=Rattus norve...820.008     38.9     29     54
GO:0017091; F:AU-rich element binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
304P26378    380   ELAV4_HUMAN ELAV-like protein 4 OS=Homo sapie...820.008     38.9     29     54
GO:0017091; F:AU-rich element binding; IDA:UniProtKB.::GO:0003730; F:mRNA 3'-UTR binding; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; TAS:ProtInc.
305Q5R8F7    636   PABP1_PONAB Polyadenylate-binding protein 1 O...840.56     33.5     23     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:2000623; P:negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; ISS:UniProtKB.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
306P11940    636   PABP1_HUMAN Polyadenylate-binding protein 1 O...840.56     33.5     23     49GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; TAS:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0008494; F:translation activator activity; TAS:UniProtKB.
GO:0006378; P:mRNA polyadenylation; TAS:UniProtKB.::GO:0048255; P:mRNA stabilization; TAS:UniProtKB.::GO:2000623; P:negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.::GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.::GO:0006413; P:translational initiation; TAS:Reactome.
307P61286    636   PABP1_BOVIN Polyadenylate-binding protein 1 O...840.56     33.5     23     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:AgBase.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:2000623; P:negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; ISS:UniProtKB.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
308Q9CQT2    265   RBM7_MOUSE RNA-binding protein 7 OS=Mus muscu...720.00007     44.7     31     64
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
309B4LVR8    259   EI3G2_DROVI Eukaryotic translation initiation...690.00007     44.7     30     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
310Q32P51    320   RA1L2_HUMAN Heterogeneous nuclear ribonucleop...535     30.4     28     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
311Q8WXA9    508   SREK1_HUMAN Splicing regulatory glutamine/lys...760.00007     44.7     36     55GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
312P17130    365   ROA1_XENLA Heterogeneous nuclear ribonucleopr...521.2     32.3     27     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
313Q1LZD9    520   PSPC1_BOVIN Paraspeckle component 1 OS=Bos ta...1000.00008     44.7     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
314P0C8Z4    992   RMXL3_PANTR RNA-binding motif protein, X-link...750.00008     45.1     29     55
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
315Q99729    332   ROAA_HUMAN Heterogeneous nuclear ribonucleopr...950.00008     44.7     24     51GO:0005737; C:cytoplasm; ISS:HGNC.::GO:0005634; C:nucleus; ISS:HGNC.::GO:0030529; C:ribonucleoprotein complex; IDA:UniProtKB.
GO:0003729; F:mRNA binding; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0001837; P:epithelial to mesenchymal transition; ISS:HGNC.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:HGNC.
316Q5ZK88    523   PSPC1_CHICK Paraspeckle component 1 OS=Gallus...1000.00008     44.7     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
317Q9H361    631   PABP3_HUMAN Polyadenylate-binding protein 3 O...841.4     32.3     21     48GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; IDA:UniProtKB.
GO:0016071; P:mRNA metabolic process; NAS:UniProtKB.
318Q5U1W5    244   U1SBP_RAT U11/U12 small nuclear ribonucleopro...780.00009     44.3     29     56
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
319Q9BRL6    282   SRSF8_HUMAN Serine/arginine-rich splicing fac...700.00009     44.3     29     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
320P51991    378   ROA3_HUMAN Heterogeneous nuclear ribonucleopr...503.7     31.2     24     56GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; TAS:ProtInc.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.
321Q6URK4    379   ROA3_RAT Heterogeneous nuclear ribonucleoprot...503.7     31.2     24     56GO:0005737; C:cytoplasm; IDA:RGD.::GO:0030530; C:heterogeneous nuclear ribonucleoprotein complex; IDA:RGD.::GO:0043005; C:neuron projection; IDA:RGD.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003729; F:mRNA binding; IMP:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0051033; F:RNA transmembrane transporter activity; IMP:RGD.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IMP:RGD.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
322Q8BG05    379   ROA3_MOUSE Heterogeneous nuclear ribonucleopr...503.7     31.2     24     56
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
323Q8WXF0    261   SRS12_HUMAN Serine/arginine-rich splicing fac...750.0001     44.3     35     52GO:0005654; C:nucleoplasm; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; NAS:UniProtKB.::GO:0050733; F:RS domain binding; NAS:UniProtKB.::GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
GO:0000244; P:assembly of spliceosomal tri-snRNP; NAS:UniProtKB.::GO:0016482; P:cytoplasmic transport; ISS:UniProtKB.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0000395; P:nuclear mRNA 5'-splice site recognition; IDA:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.
324Q99070    168   GRP2_SORBI Glycine-rich RNA-binding protein 2...750.0001     43.5     24     53
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
325Q8L716    589   U2A2B_ARATH Splicing factor U2af large subuni...720.0001     44.3     33     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
326O23212    573   U2A2A_ARATH Splicing factor U2af large subuni...720.0001     44.3     32     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0042742; P:defense response to bacterium; IEP:TAIR.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
327Q4KLH4    522   PSPC1_RAT Paraspeckle component 1 OS=Rattus n...1000.0001     44.3     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
328Q8R326    523   PSPC1_MOUSE Paraspeckle component 1 OS=Mus mu...1000.0001     44.3     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0042382; C:paraspeckles; IDA:MGI.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
329Q9D384    244   U1SBP_MOUSE U11/U12 small nuclear ribonucleop...780.0001     43.9     29     56GO:0005689; C:U12-type spliceosomal complex; ISS:HGNC.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
330A4RHN3    303   EIF3G_MAGO7 Eukaryotic translation initiation...670.0001     43.9     25     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
331Q0VFL7    291   RALYL_XENTR RNA-binding Raly-like protein OS=...1010.0001     43.9     32     49
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
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