UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YIR005W

Length:

148

Number of sequences:

5887

Description:

YIR005W IST3 SGDID:S000001444, Chr IX from 364889-365335, Genome Release 64-1-1, Verified ORF, "Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
151	A6NEQ0	496	RBY1E_HUMAN RNA-binding motif protein, Y chro...	74	0.000003	48.9	34	62	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
152	P0C7P1	496	RBY1D_HUMAN RNA-binding motif protein, Y chro...	74	0.000003	48.9	34	62	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
153	P0DJD4	496	RBY1C_HUMAN RNA-binding motif protein, Y chro...	74	0.000003	48.9	34	62	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
154	P0DJD3	496	RBY1A_HUMAN RNA-binding motif protein, Y chro...	74	0.000003	48.9	34	62	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
155	Q9IBD1	452	CELF3_DANRE CUGBP Elav-like family member 3 O...	70	0.16	35	24	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048026; P:positive regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.
156	A6NDE4	496	RBY1B_HUMAN RNA-binding motif protein, Y chro...	74	0.000004	48.9	34	62	GO:0005634; C:nucleus; TAS:UniProtKB.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; NAS:UniProtKB.
									GO:0008584; P:male gonad development; IMP:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IDA:UniProtKB.::GO:0007283; P:spermatogenesis; TAS:UniProtKB.
157	O93235	166	CIRBA_XENLA Cold-inducible RNA-binding protei...	79	0.000004	47	29	54	GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0019899; F:enzyme binding; ISS:UniProtKB.::GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0070181; F:SSU rRNA binding; ISS:UniProtKB.::GO:0030371; F:translation repressor activity; ISS:UniProtKB.
									GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0007369; P:gastrulation; IMP:UniProtKB.::GO:0072004; P:kidney field specification; IMP:UniProtKB.::GO:0048255; P:mRNA stabilization; ISS:UniProtKB.::GO:0060212; P:negative regulation of nuclear-transcribed mRNA poly(A) tail shortening; ISS:UniProtKB.::GO:0022008; P:neurogenesis; IMP:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0048793; P:pronephros development; IMP:UniProtKB.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0034063; P:stress granule assembly; ISS:UniProtKB.
158	B4PP90	273	EI3G2_DROYA Eukaryotic translation initiation...	69	0.000004	48.1	32	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
159	Q28BZ1	174	RBM8A_XENTR RNA-binding protein 8A OS=Xenopus...	78	0.000004	47	31	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
160	Q6DEY7	629	EPAB_XENTR Embryonic polyadenylate-binding pr...	84	0.091	35.8	24	50	GO:0005737; C:cytoplasm; ISS:UniProtKB.
									GO:0031370; F:eukaryotic initiation factor 4G binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; ISS:UniProtKB.::GO:0043621; F:protein self-association; ISS:UniProtKB.
									GO:0043009; P:chordate embryonic development; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048255; P:mRNA stabilization; ISS:UniProtKB.::GO:0060212; P:negative regulation of nuclear-transcribed mRNA poly(A) tail shortening; ISS:UniProtKB.::GO:0006412; P:translation; IEA:UniProtKB-KW.
161	A2Q848	731	PABP_ASPNC Polyadenylate-binding protein, cyt...	91	0.47	33.9	22	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
162	P53316	781	YG5B_YEAST Uncharacterized RNA-binding protei...	97	0.000005	48.5	28	54	GO:0010494; C:cytoplasmic stress granule; IDA:SGD.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
163	Q6GR16	629	EPABB_XENLA Embryonic polyadenylate-binding p...	84	0.34	34.3	24	49	GO:0005737; C:cytoplasm; ISS:UniProtKB.
									GO:0031370; F:eukaryotic initiation factor 4G binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008143; F:poly(A) RNA binding; ISS:UniProtKB.::GO:0043621; F:protein self-association; ISS:UniProtKB.
									GO:0043009; P:chordate embryonic development; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048255; P:mRNA stabilization; ISS:UniProtKB.::GO:0060212; P:negative regulation of nuclear-transcribed mRNA poly(A) tail shortening; ISS:UniProtKB.::GO:0006412; P:translation; IEA:UniProtKB-KW.
164	Q9DF42	174	RB8AA_XENLA RNA-binding protein 8A-A OS=Xenop...	78	0.000006	47	31	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
165	B3NYY7	273	EI3G2_DROER Eukaryotic translation initiation...	66	0.000006	47.8	32	62	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
166	Q6PH90	174	RB8AB_XENLA RNA-binding protein 8A-B OS=Xenop...	78	0.000006	47	31	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
167	Q9JII5	406	DAZP1_MOUSE DAZ-associated protein 1 OS=Mus m...	102	0.015	38.1	21	48	GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
168	Q96EP5	407	DAZP1_HUMAN DAZ-associated protein 1 OS=Homo ...	102	0.019	37.7	23	48	GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; TAS:ProtInc.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; TAS:ProtInc.
169	Q9BYG3	293	MK67I_HUMAN MKI67 FHA domain-interacting nucl...	72	0.000006	47.8	29	56	GO:0000794; C:condensed nuclear chromosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IDA:UniProtKB.
									GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.::GO:0006461; P:protein complex assembly; NAS:UniProtKB.::GO:0016072; P:rRNA metabolic process; NAS:UniProtKB.::GO:0009303; P:rRNA transcription; NAS:UniProtKB.
170	Q74ZS6	585	PABP_ASHGO Polyadenylate-binding protein, cyt...	72	5.6	30.8	22	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
171	Q0CPF9	286	EIF3G_ASPTN Eukaryotic translation initiation...	70	0.000007	47.8	30	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
172	Q5D018	174	RBM8A_DANRE RNA-binding protein 8A OS=Danio r...	78	0.000007	46.6	29	59	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
173	Q3T106	235	SRSF7_BOVIN Serine/arginine-rich splicing fac...	93	0.000007	47.4	30	52	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
174	Q6PFR5	281	TRA2A_MOUSE Transformer-2 protein homolog alp...	78	0.000008	47.4	32	58	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
175	Q13595	282	TRA2A_HUMAN Transformer-2 protein homolog alp...	78	0.000008	47.4	32	58	GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.
176	Q16629	238	SRSF7_HUMAN Serine/arginine-rich splicing fac...	93	0.000008	47.4	30	52	GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.::GO:0006406; P:mRNA export from nucleus; TAS:Reactome.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:Reactome.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
177	Q0U1G2	744	PABP_PHANO Polyadenylate-binding protein, cyt...	91	0.18	35	22	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
178	P09651	372	ROA1_HUMAN Heterogeneous nuclear ribonucleopr...	52	3.7	31.2	25	54	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:HGNC.::GO:0030530; C:heterogeneous nuclear ribonucleoprotein complex; TAS:ProtInc.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; IDA:HGNC.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003697; F:single-stranded DNA binding; IDA:HGNC.::GO:0003727; F:single-stranded RNA binding; IC:HGNC.
									GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0051170; P:nuclear import; IDA:HGNC.::GO:0006405; P:RNA export from nucleus; IC:HGNC.
179	B3MSP2	269	EI3G2_DROAN Eukaryotic translation initiation...	69	0.000008	47.4	32	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
180	Q2H0U6	303	EIF3G_CHAGB Eukaryotic translation initiation...	72	0.000009	47.4	28	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
181	A5DW14	661	PABP_LODEL Polyadenylate-binding protein, cyt...	72	0.21	34.7	25	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.

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