Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIR005W
Length:
148
Number of sequences:
5887
Description:
YIR005W IST3 SGDID:S000001444, Chr IX from 364889-365335, Genome Release 64-1-1, Verified ORF, "Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q8QZY9    424   SF3B4_MOUSE Splicing factor 3B subunit 4 OS=M...810.0003     42.7     22     58GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
122Q3ZC12    320   EIF3G_BOVIN Eukaryotic translation initiation...670.000001     50.1     31     60GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
123Q8TBF4    217   ZCRB1_HUMAN Zinc finger CCHC-type and RNA-bin...900.000001     49.3     31     54GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005689; C:U12-type spliceosomal complex; IDA:HGNC.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IC:HGNC.
124Q15427    424   SF3B4_HUMAN Splicing factor 3B subunit 4 OS=H...810.0003     42.7     22     58GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005689; C:U12-type spliceosomal complex; IDA:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:HGNC.
125Q6CSV3    592   PABP_KLULA Polyadenylate-binding protein, cyt...860.047     36.6     26     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
126Q2UK72    765   PABP_ASPOR Polyadenylate-binding protein, cyt...910.64     33.5     22     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
127Q6DJI8    308   EI3GA_XENLA Eukaryotic translation initiation...670.000001     49.7     31     60GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
128P49310    166   GRP1_SINAL Glycine-rich RNA-binding protein G...750.000002     48.1     28     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
129P53883    403   NOP13_YEAST Nucleolar protein 13 OS=Saccharom...900.000002     49.7     27     61GO:0005730; C:nucleolus; IDA:SGD.::GO:0030684; C:preribosome; IDA:SGD.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
130Q9ZUU4    289   ROC1_ARATH Ribonucleoprotein At2g37220, chlor...810.009     38.5     26     47GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.::GO:0010319; C:stromule; IDA:TAIR.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008266; F:poly(U) RNA binding; IDA:TAIR.
GO:0045087; P:innate immune response; IDA:TAIR.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0009737; P:response to abscisic acid stimulus; IEP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.
131A3LXL0    632   PABP_PICST Polyadenylate-binding protein, cyt...800.00007     45.1     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
132Q1JQ73    337   ELV1A_XENLA ELAV-like protein 1-A OS=Xenopus ...840.002     40.4     27     54GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0030529; C:ribonucleoprotein complex; IDA:UniProtKB.
GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008266; F:poly(U) RNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007369; P:gastrulation; IMP:UniProtKB.::GO:0008298; P:intracellular mRNA localization; IMP:UniProtKB.::GO:0048255; P:mRNA stabilization; IGI:UniProtKB.::GO:0031440; P:regulation of mRNA 3'-end processing; IC:UniProtKB.
133Q1DXH0    768   PABP_COCIM Polyadenylate-binding protein, cyt...910.71     33.5     22     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
134Q9V3G3    300   PPIE_DROME Peptidyl-prolyl cis-trans isomeras...940.000002     49.3     27     52GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.::GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.
135P70372    326   ELAV1_MOUSE ELAV-like protein 1 OS=Mus muscul...970.021     37.7     24     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI.
GO:0017091; F:AU-rich element binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; ISS:UniProtKB.::GO:0045727; P:positive regulation of translation; IMP:MGI.
136Q15717    326   ELAV1_HUMAN ELAV-like protein 1 OS=Homo sapie...970.012     38.1     24     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0017091; F:AU-rich element binding; IDA:UniProtKB.::GO:0003729; F:mRNA binding; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:UniProtKB.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0045727; P:positive regulation of translation; IDA:MGI.
137Q8JIY8    269   MK67I_DANRE MKI67 FHA domain-interacting nucl...1030.000002     48.9     24     50GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
138Q56JZ7    217   ZCRB1_BOVIN Zinc finger CCHC-type and RNA-bin...900.000002     48.5     31     53GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
139Q91579    462   CEL3A_XENLA CUGBP Elav-like family member 3-A...627.1     30.4     24     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0048026; P:positive regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.
140Q23121    312   RSP1_CAEEL Probable splicing factor, arginine...770.000002     48.9     35     56GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; NAS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0001703; P:gastrulation with mouth forming first; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0008380; P:RNA splicing; NAS:UniProtKB.::GO:0007283; P:spermatogenesis; IGI:UniProtKB.
141Q15415    496   RBY1F_HUMAN RNA-binding motif protein, Y chro...740.000002     49.3     34     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; NAS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; NAS:UniProtKB.
142A1CRM1    754   PABP_ASPCL Polyadenylate-binding protein, cyt...811.7     32.3     21     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
143P42731    629   PABP2_ARATH Polyadenylate-binding protein 2 O...727.2     30.4     24     49GO:0005829; C:cytosol; IDA:TAIR.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0009651; P:response to salt stress; IEP:TAIR.
144Q01085    375   TIAR_HUMAN Nucleolysin TIAR OS=Homo sapiens (...730.007     38.9     32     60GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0005764; C:lysosome; TAS:ProtInc.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; TAS:ProtInc.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006952; P:defense response; TAS:ProtInc.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
145Q7ZWA3    379   RBMX_DANRE RNA-binding motif protein, X chrom...750.000003     48.9     32     59GO:0071013; C:catalytic step 2 spliceosome; ISS:UniProtKB.::GO:0070062; C:extracellular vesicular exosome; ISS:UniProtKB.::GO:0005719; C:nuclear euchromatin; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0001047; F:core promoter binding; ISS:UniProtKB.::GO:0003729; F:mRNA binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0071347; P:cellular response to interleukin-1; ISS:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048025; P:negative regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0048026; P:positive regulation of nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
146P70318    392   TIAR_MOUSE Nucleolysin TIAR OS=Mus musculus (...900.76     33.1     29     51GO:0010494; C:cytoplasmic stress granule; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0017091; F:AU-rich element binding; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007281; P:germ cell development; IMP:MGI.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0017145; P:stem cell division; IMP:MGI.
147Q2GSX8    783   PABP_CHAGB Polyadenylate-binding protein, cyt...910.055     36.6     22     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
148Q6CDH3    629   PABP_YARLI Polyadenylate-binding protein, cyt...722.1     32     25     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
149O43040    363   CTF1_SCHPO Cleavage and termination factor 1 ...1060.000003     48.9     27     55GO:0005829; C:cytosol; IDA:PomBase.::GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IDA:PomBase.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006378; P:mRNA polyadenylation; IC:PomBase.
150Q5AJS6    841   MRD1_CANAL Multiple RNA-binding domain-contai...1660.000003     49.3     23     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
151A6NEQ0    496   RBY1E_HUMAN RNA-binding motif protein, Y chro...740.000003     48.9     34     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
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