UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YIR002C

Length:

993

Number of sequences:

5887

Description:

YIR002C MPH1 SGDID:S000001441, Chr IX from 360396-357415, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of the DEAH family of helicases, functions in an error-free DNA damage bypass pathway that involves homologous recombination, binds to flap DNA and stimulates activity of Rad27p and Dna2p; mutations confer a mutator phenotype"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
91	A1D071	399	FAL1_NEOFI ATP-dependent RNA helicase fal1 OS...	121	0.000003	54.3	29	50	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
92	Q0ILZ4	628	RH9_ORYSJ DEAD-box ATP-dependent RNA helicase...	103	0.000003	54.7	32	56
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
93	A1C595	399	FAL1_ASPCL ATP-dependent RNA helicase fal1 OS...	121	0.000003	54.3	29	50	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
94	P96614	494	CSHA_BACSU DEAD-box ATP-dependent RNA helicas...	133	0.000003	54.3	30	44	GO:0043590; C:bacterial nucleoid; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004004; F:ATP-dependent RNA helicase activity; IDA:UniProtKB.::GO:0003723; F:RNA binding; IDA:UniProtKB.
									GO:0009409; P:response to cold; IGI:UniProtKB.::GO:0010501; P:RNA secondary structure unwinding; IDA:UniProtKB.
95	A7LFZ6	1657	DCL4_ORYSJ Endoribonuclease Dicer homolog 4 O...	103	0.000004	54.7	31	55	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.
									GO:0010492; P:maintenance of shoot apical meristem identity; IMP:UniProtKB.::GO:0009944; P:polarity specification of adaxial/abaxial axis; IMP:UniProtKB.::GO:0010267; P:production of ta-siRNAs involved in RNA interference; IDA:UniProtKB.::GO:0048608; P:reproductive structure development; IMP:UniProtKB.
96	Q0DBS1	590	RH51_ORYSJ Putative DEAD-box ATP-dependent RN...	120	0.000004	54.7	28	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
97	P0CR00	484	RRP3_CRYNJ ATP-dependent rRNA helicase RRP3 O...	95	0.000004	54.3	34	51	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
98	P0CR01	484	RRP3_CRYNB ATP-dependent rRNA helicase RRP3 O...	95	0.000004	54.3	34	51	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
99	Q9NR30	783	DDX21_HUMAN Nucleolar RNA helicase 2 OS=Homo ...	81	0.000004	54.3	40	54	GO:0005730; C:nucleolus; IDA:HPA.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
100	Q9GLV6	940	DDX58_PIG Probable ATP-dependent RNA helicase...	81	0.000005	54.3	40	57	GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; ISS:UniProtKB.::GO:0005923; C:tight junction; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.::GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0045087; P:innate immune response; ISS:UniProtKB.::GO:0002230; P:positive regulation of defense response to virus by host; ISS:UniProtKB.::GO:0032727; P:positive regulation of interferon-alpha production; ISS:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0039529; P:RIG-I signaling pathway; ISS:UniProtKB.
101	Q75EW9	487	RRP3_ASHGO ATP-dependent rRNA helicase RRP3 O...	99	0.000005	53.9	35	48	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
102	Q65N62	487	CSHA_BACLD DEAD-box ATP-dependent RNA helicas...	133	0.000005	53.9	30	44	GO:0043590; C:bacterial nucleoid; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; ISS:UniProtKB.
103	Q4P184	397	FAL1_USTMA ATP-dependent RNA helicase FAL1 OS...	97	0.000005	53.5	30	55	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
104	Q4P3U9	551	RRP3_USTMA ATP-dependent rRNA helicase RRP3 O...	167	0.000005	53.9	25	44	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
105	Q2VF18	1451	DCL2_CRYPA Dicer-like protein 2 OS=parasitica...	127	0.000006	54.3	28	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.
106	Q9SA27	491	RH36_ARATH DEAD-box ATP-dependent RNA helicas...	83	0.000006	53.9	31	49	GO:0005634; C:nucleus; IDA:TAIR.::GO:0090406; C:pollen tube; IDA:TAIR.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR.
									GO:0009561; P:megagametogenesis; IMP:TAIR.::GO:0009791; P:post-embryonic development; IMP:TAIR.::GO:0006364; P:rRNA processing; IMP:TAIR.
107	Q10MH8	770	RH24_ORYSJ DEAD-box ATP-dependent RNA helicas...	102	0.000006	53.9	31	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
108	Q6C024	575	PRP28_YARLI Pre-mRNA-splicing ATP-dependent R...	124	0.000006	53.9	31	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
109	P25888	454	RHLE_ECOLI ATP-dependent RNA helicase rhlE OS...	205	0.000006	53.5	26	41	GO:0005840; C:ribosome; IDA:EcoCyc.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IDA:EcoCyc.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
110	Q59PR3	440	DBP8_CANAL ATP-dependent RNA helicase DBP8 OS...	177	0.000006	53.5	27	42	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
111	Q8GXD6	558	RH49_ARATH DEAD-box ATP-dependent RNA helicas...	76	0.000006	53.5	33	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
112	Q61656	614	DDX5_MOUSE Probable ATP-dependent RNA helicas...	117	0.000007	53.5	30	50	GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003724; F:RNA helicase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
									GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; IMP:UniProtKB.::GO:2001014; P:regulation of skeletal muscle cell differentiation; IMP:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
113	A1D1E3	738	ROK1_NEOFI ATP-dependent RNA helicase rok1 OS...	100	0.000007	53.9	30	56	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
114	Q11039	563	DEAD_MYCTU Cold-shock DEAD box protein A homo...	124	0.000007	53.5	31	48	GO:0005829; C:cytosol; IDA:MTBBASE.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
115	Q4WRH5	739	ROK1_ASPFU ATP-dependent RNA helicase rok1 OS...	100	0.000008	53.5	30	56	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
116	Q5R4I9	614	DDX5_PONAB Probable ATP-dependent RNA helicas...	117	0.000008	53.5	30	50	GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003724; F:RNA helicase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; ISS:UniProtKB.::GO:2001014; P:regulation of skeletal muscle cell differentiation; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
117	Q2GWJ5	394	FAL1_CHAGB ATP-dependent RNA helicase FAL1 OS...	115	0.000008	53.1	30	50	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
118	A5A6J2	614	DDX5_PANTR Probable ATP-dependent RNA helicas...	117	0.000008	53.5	30	50	GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003724; F:RNA helicase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; ISS:UniProtKB.::GO:2001014; P:regulation of skeletal muscle cell differentiation; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
119	Q4R6M5	614	DDX5_MACFA Probable ATP-dependent RNA helicas...	117	0.000008	53.5	30	50	GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003724; F:RNA helicase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; ISS:UniProtKB.::GO:2001014; P:regulation of skeletal muscle cell differentiation; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
120	Q5VNM3	404	RH2_ORYSJ DEAD-box ATP-dependent RNA helicase...	115	0.000008	53.1	30	47	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
121	P17844	614	DDX5_HUMAN Probable ATP-dependent RNA helicas...	117	0.000008	53.5	30	50	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.
									GO:0050681; F:androgen receptor binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.::GO:0036002; F:pre-mRNA binding; IDA:UniProtKB.::GO:0003724; F:RNA helicase activity; IMP:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
									GO:0016049; P:cell growth; NAS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IMP:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; ISS:UniProtKB.::GO:2001014; P:regulation of skeletal muscle cell differentiation; ISS:UniProtKB.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.

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