Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIR002C
Length:
993
Number of sequences:
5887
Description:
YIR002C MPH1 SGDID:S000001441, Chr IX from 360396-357415, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of the DEAH family of helicases, functions in an error-free DNA damage bypass pathway that involves homologous recombination, binds to flap DNA and stimulates activity of Rad27p and Dna2p; mutations confer a mutator phenotype"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q10055    394   FAL1_SCHPO ATP-dependent RNA helicase fal1 OS...850.00000003     60.5     34     58GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; ISS:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:PomBase.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; ISS:PomBase.
32Q89AF9    602   DEAD_BUCBP Cold-shock DEAD box protein A homo...1250.00000003     61.2     33     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
33A5D7C1    596   DDX52_BOVIN Probable ATP-dependent RNA helica...740.00000008     60.1     36     62GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
34Q8K301    598   DDX52_MOUSE Probable ATP-dependent RNA helica...740.00000008     59.7     36     64GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
35Q99PT0    598   DDX52_RAT Probable ATP-dependent RNA helicase...740.00000009     59.7     36     64GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003724; F:RNA helicase activity; NAS:RGD.
GO:0006364; P:rRNA processing; TAS:RGD.
36Q8L7S8    748   RH3_ARATH DEAD-box ATP-dependent RNA helicase...830.0000001     59.7     34     61GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
37Q9Y2R4    599   DDX52_HUMAN Probable ATP-dependent RNA helica...740.0000001     59.3     35     64GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
38Q96C10    678   DHX58_HUMAN Probable ATP-dependent RNA helica...2230.0000002     58.9     26     45GO:0005737; C:cytoplasm; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0045824; P:negative regulation of innate immune response; IDA:UniProtKB.::GO:0039534; P:negative regulation of MDA-5 signaling pathway; IMP:UniProtKB.::GO:0039536; P:negative regulation of RIG-I signaling pathway; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; IDA:UniProtKB.::GO:1900245; P:positive regulation of MDA-5 signaling pathway; ISS:UniProtKB.::GO:1900246; P:positive regulation of RIG-I signaling pathway; ISS:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; ISS:UniProtKB.
39P0A4D8    524   EXP9_STRR6 Probable ATP-dependent RNA helicas...1490.0000002     58.5     29     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
40P0A4D7    524   EXP9_STRPN Probable ATP-dependent RNA helicas...1490.0000002     58.5     29     47GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
41O95786    925   DDX58_HUMAN Probable ATP-dependent RNA helica...2050.0000003     58.5     25     44GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0032587; C:ruffle membrane; IDA:UniProtKB.::GO:0005923; C:tight junction; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003727; F:single-stranded RNA binding; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0009597; P:detection of virus; IDA:BHF-UCL.::GO:0045087; P:innate immune response; IMP:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0002230; P:positive regulation of defense response to virus by host; IMP:UniProtKB.::GO:0032727; P:positive regulation of interferon-alpha production; IDA:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IC:BHF-UCL.::GO:0042993; P:positive regulation of transcription factor import into nucleus; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0030334; P:regulation of cell migration; IDA:UniProtKB.::GO:0034344; P:regulation of type III interferon production; TAS:UniProtKB.::GO:0039529; P:RIG-I signaling pathway; IMP:UniProtKB.
42Q9LUW5    616   RH53_ARATH DEAD-box ATP-dependent RNA helicas...1030.0000004     57.8     34     57GO:0005618; C:cell wall; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0043234; C:protein complex; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000373; P:Group II intron splicing; IMP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.
43Q6CH58    480   RRP3_YARLI ATP-dependent rRNA helicase RRP3 O...720.0000005     57.4     42     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
44P0C2N8    829   DRS1_NEUCR ATP-dependent RNA helicase drs-1 O...1110.0000005     57.8     31     53GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
45Q1DTB3    399   FAL1_COCIM ATP-dependent RNA helicase FAL1 OS...1210.0000005     57     31     50GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
46A6QSQ0    450   FAL1_AJECN ATP-dependent RNA helicase FAL1 OS...1210.0000006     57     31     50GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
47P0CQ79    605   DBP3_CRYNB ATP-dependent RNA helicase DBP3 OS...1090.0000006     57     34     49GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
48P0CQ78    605   DBP3_CRYNJ ATP-dependent RNA helicase DBP3 OS...1090.0000007     57     34     49GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
49Q9LIH9    568   RH51_ARATH DEAD-box ATP-dependent RNA helicas...780.0000007     57     37     53GO:0005730; C:nucleolus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
50Q7ZVA6    406   IF4A3_DANRE Eukaryotic initiation factor 4A-I...1150.0000007     56.6     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
51Q8L4E9    501   RH36_ORYSJ DEAD-box ATP-dependent RNA helicas...720.0000007     56.6     38     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
52P0CQ98    1072   PRP5_CRYNJ Pre-mRNA-processing ATP-dependent ...890.0000008     57     35     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
53P0CQ99    1072   PRP5_CRYNB Pre-mRNA-processing ATP-dependent ...890.0000008     57     35     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
54Q9H8H2    851   DDX31_HUMAN Probable ATP-dependent RNA helica...770.0000009     57     35     55GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
55O42226    414   I4A3B_XENLA Eukaryotic initiation factor 4A-I...1150.000001     55.8     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
56Q81IT9    533   CSHA_BACCR DEAD-box ATP-dependent RNA helicas...970.000001     56.2     34     47GO:0043590; C:bacterial nucleoid; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; ISS:UniProtKB.
57Q6HPE6    528   CSHA_BACHK DEAD-box ATP-dependent RNA helicas...970.000001     56.2     34     47GO:0043590; C:bacterial nucleoid; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; ISS:UniProtKB.
58Q81VG0    528   CSHA_BACAN DEAD-box ATP-dependent RNA helicas...970.000001     56.2     34     47GO:0043590; C:bacterial nucleoid; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; ISS:UniProtKB.
59A0R8U6    528   CSHA_BACAH DEAD-box ATP-dependent RNA helicas...970.000001     56.2     34     47GO:0043590; C:bacterial nucleoid; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; ISS:UniProtKB.
60Q63GX5    528   CSHA_BACCZ DEAD-box ATP-dependent RNA helicas...970.000001     56.2     34     47GO:0043590; C:bacterial nucleoid; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.::GO:0003723; F:RNA binding; ISS:UniProtKB.
61Q5U526    415   I4A3A_XENLA Eukaryotic initiation factor 4A-I...1150.000001     55.8     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
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