Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL139C
Length:
245
Number of sequences:
5887
Description:
YIL139C REV7 SGDID:S000001401, Chr IX from 88716-87979, Genome Release 64-1-1, reverse complement, Verified ORF, "Accessory subunit of DNA polymerase zeta, involved in translesion synthesis during post-replication repair; required for mutagenesis induced by DNA damage; involved in double-strand break repair"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38927    245   REV7_YEAST DNA polymerase zeta processivity s...2451e-179     500     100     100GO:0005739; C:mitochondrion; IDA:SGD.::GO:0016035; C:zeta DNA polymerase complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0070987; P:error-free translesion synthesis; IDA:SGD.::GO:0042276; P:error-prone translesion synthesis; IDA:SGD.
2Q568H3    211   MD2L2_DANRE Mitotic spindle assembly checkpoi...880.23     35.8     30     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q0E7J8    213   REV7_SCHPO DNA polymerase zeta processivity s...750.38     35     32     55GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
4Q556Y9    203   MD2L1_DICDI Mitotic spindle assembly checkpoi...1230.66     34.3     24     48GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:dictyBase.
5P40958    196   MAD2_YEAST Mitotic spindle checkpoint compone...1411.4     33.1     26     47GO:0033597; C:mitotic checkpoint complex; IDA:SGD.::GO:0005643; C:nuclear pore; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051312; P:chromosome decondensation; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IGI:SGD.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IGI:SGD.
6Q13257    205   MD2L1_HUMAN Mitotic spindle assembly checkpoi...1222.1     32.7     29     45GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; IDA:UniProtKB.::GO:0090267; P:positive regulation of mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.
7B0BT71    513   NHAB_ACTPJ Na(+)/H(+) antiporter nhaB OS=Acti...342.5     33.1     38     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro.
8B3H0G7    513   NHAB_ACTP7 Na(+)/H(+) antiporter nhaB OS=Acti...342.5     33.1     38     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro.
9Q7VKY3    513   NHAB_HAEDU Na(+)/H(+) antiporter nhaB OS=Haem...272.6     32.7     44     74GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro.
10Q9Z1B5    205   MD2L1_MOUSE Mitotic spindle assembly checkpoi...1212.6     32.3     25     45GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0000922; C:spindle pole; IDA:MGI.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:MGI.::GO:0000070; P:mitotic sister chromatid segregation; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0090267; P:positive regulation of mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.
11Q9UI95    211   MD2L2_HUMAN Mitotic spindle assembly checkpoi...886.6     31.2     28     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005819; C:spindle; IDA:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; IDA:UniProtKB.
GO:0008432; F:JUN kinase binding; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; IDA:UniProtKB.::GO:0006302; P:double-strand break repair; IGI:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:ProtInc.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; IDA:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0001558; P:regulation of cell growth; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12D3Z8D9    211   MD2L2_RAT Mitotic spindle assembly checkpoint...886.9     31.2     28     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB.
GO:0008432; F:JUN kinase binding; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13Q9D752    211   MD2L2_MOUSE Mitotic spindle assembly checkpoi...886.9     31.2     28     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB.
GO:0008432; F:JUN kinase binding; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14Q2KIP7    211   MD2L2_BOVIN Mitotic spindle assembly checkpoi...888.5     30.8     28     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; ISS:UniProtKB.::GO:0016035; C:zeta DNA polymerase complex; ISS:UniProtKB.
GO:0008432; F:JUN kinase binding; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042772; P:DNA damage response, signal transduction resulting in transcription; ISS:UniProtKB.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15P36345    322   VP40_NPVHZ Structural glycoprotein p40 OS=sin...558.9     31.2     27     56GO:0019012; C:virion; IEA:UniProtKB-SubCell.
GO:0005198; F:structural molecule activity; IEA:InterPro.
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