UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YIL138C

Length:

161

Number of sequences:

5887

Description:

YIL138C TPM2 SGDID:S000001400, Chr IX from 89715-89230, Genome Release 64-1-1, reverse complement, Verified ORF, "Minor isoform of tropomyosin, binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; appears to have distinct and also overlapping functions with Tpm1p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P40414	161	TPM2_YEAST Tropomyosin-2 OS=Saccharomyces cer...	161	5e-102	296	100	100	GO:0032432; C:actin filament bundle; IDA:SGD.::GO:0000142; C:cellular bud neck contractile ring; IDA:SGD.
									GO:0003786; F:actin lateral binding; TAS:SGD.
									GO:0051017; P:actin filament bundle assembly; IGI:SGD.::GO:0008154; P:actin polymerization or depolymerization; TAS:SGD.::GO:0007118; P:budding cell apical bud growth; TAS:SGD.::GO:0007119; P:budding cell isotropic bud growth; TAS:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0006887; P:exocytosis; TAS:SGD.::GO:0008298; P:intracellular mRNA localization; TAS:SGD.::GO:0000001; P:mitochondrion inheritance; TAS:SGD.::GO:0000011; P:vacuole inheritance; TAS:SGD.
2	P17536	199	TPM1_YEAST Tropomyosin-1 OS=Saccharomyces cer...	199	3e-55	179	53	71	GO:0032432; C:actin filament bundle; IDA:SGD.::GO:0000142; C:cellular bud neck contractile ring; IDA:SGD.
									GO:0003786; F:actin lateral binding; TAS:SGD.
									GO:0051017; P:actin filament bundle assembly; IGI:SGD.::GO:0008154; P:actin polymerization or depolymerization; TAS:SGD.::GO:0007118; P:budding cell apical bud growth; TAS:SGD.::GO:0007119; P:budding cell isotropic bud growth; TAS:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0006887; P:exocytosis; TAS:SGD.::GO:0008298; P:intracellular mRNA localization; TAS:SGD.::GO:0000001; P:mitochondrion inheritance; TAS:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0000011; P:vacuole inheritance; TAS:SGD.
3	Q02088	161	TPM_SCHPO Tropomyosin OS=Schizosaccharomyces ...	164	0.000000000002	65.1	36	65	GO:0032432; C:actin filament bundle; IDA:PomBase.::GO:0005826; C:actomyosin contractile ring; IDA:PomBase.
									GO:0003779; F:actin binding; TAS:PomBase.
									GO:0071519; P:actin filament bundle assembly involved in actomyosin contractile ring formation; NAS:PomBase.::GO:0032220; P:plasma membrane fusion involved in cytogamy; IMP:PomBase.
4	Q60675	3106	LAMA2_MOUSE Laminin subunit alpha-2 OS=Mus mu...	173	0.000006	48.9	27	48	GO:0005606; C:laminin-1 complex; IEA:InterPro.
									GO:0005102; F:receptor binding; IEA:InterPro.
									GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.
5	O97162	284	TPM_BOOMI Tropomyosin OS=Boophilus microplus ...	169	0.000009	47.8	32	55
6	P24043	3122	LAMA2_HUMAN Laminin subunit alpha-2 OS=Homo s...	163	0.00003	46.6	28	48	GO:0005606; C:laminin-1 complex; IEA:InterPro.
									GO:0005102; F:receptor binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; TAS:ProtInc.
									GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.
7	Q8IT89	284	TPM_HAELO Tropomyosin OS=Haemaphysalis longic...	169	0.00005	45.4	31	55
8	O13335	697	NDE1_NEUCR Nuclear distribution protein nudE ...	152	3.9	31.2	22	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
									GO:0006810; P:transport; IEA:UniProtKB-KW.
9	P42638	284	TPM2_SCHMA Tropomyosin-2 OS=Schistosoma manso...	162	0.012	38.5	27	53
10	P19352	284	TPM2_CHICK Tropomyosin beta chain OS=Gallus g...	165	0.0003	43.1	30	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.
11	P91958	284	TPM_MYTGA Tropomyosin OS=Mytilus galloprovinc...	173	0.0003	43.1	29	53
12	Q25457	284	TPM_MYTED Tropomyosin OS=Mytilus edulis (Blue...	173	0.0003	43.1	29	53
13	P86704	284	TPM_PANBO Tropomyosin OS=Pandalus borealis (N...	165	0.11	35.8	25	58
14	A1KYZ2	284	TPM_PENMO Tropomyosin OS=Penaeus monodon (Gia...	141	0.39	34.3	26	58
15	Q8WXE1	791	ATRIP_HUMAN ATR-interacting protein OS=Homo s...	101	0.001	42	30	52	GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0000077; P:DNA damage checkpoint; TAS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; TAS:Reactome.
16	Q9UBC2	864	EP15R_HUMAN Epidermal growth factor receptor ...	166	1.4	32.7	18	43	GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
									GO:0005509; F:calcium ion binding; IEA:InterPro.
									GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
17	O44119	284	TPM_HOMAM Tropomyosin OS=Homarus americanus (...	129	0.81	33.1	26	58
18	O95153	1857	RIMB1_HUMAN Peripheral-type benzodiazepine re...	165	0.002	40.8	24	47	GO:0005739; C:mitochondrion; IDA:UniProtKB.
									GO:0030156; F:benzodiazepine receptor binding; IPI:UniProtKB.
19	Q23939	284	TPM_DERFA Tropomyosin OS=Dermatophagoides far...	169	0.002	40.4	30	56
20	P42636	284	TPM1_BIOGL Tropomyosin-1 OS=Biomphalaria glab...	173	0.002	40.4	27	55
21	O97192	284	TPM_HELAS Tropomyosin OS=Helix aspersa (Brown...	169	0.002	40.4	28	57
22	Q23758	284	TPM_CLOSI Tropomyosin OS=Clonorchis sinensis ...	169	0.004	39.7	30	55
23	Q86YV0	1011	RASL3_HUMAN RAS protein activator like-3 OS=H...	86	0.005	40	27	56	GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
									GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
									GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0007165; P:signal transduction; IEA:InterPro.
24	P43689	284	TPM2_BIOGL Tropomyosin-2 OS=Biomphalaria glab...	173	0.007	39.3	27	55
25	A2V735	284	TPM_CHIOP Tropomyosin OS=Chionoecetes opilio ...	155	0.31	34.3	26	55
26	Q9GZ70	284	TPM_PERVI Tropomyosin OS=Perna viridis (Tropi...	173	0.008	38.9	28	51
27	Q8JHV6	1827	LAMB4_DANRE Laminin subunit beta-4 OS=Danio r...	152	0.69	33.9	21	50	GO:0005604; C:basement membrane; IEA:UniProtKB-SubCell.
									GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
28	Q8BMG1	785	ATRIP_MOUSE ATR-interacting protein OS=Mus mu...	96	0.012	38.9	30	51	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
29	P07951	284	TPM2_HUMAN Tropomyosin beta chain OS=Homo sap...	165	0.013	38.5	28	58	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005862; C:muscle thin filament tropomyosin; TAS:ProtInc.
									GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
									GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0043462; P:regulation of ATPase activity; IDA:UniProtKB.
30	Q8T380	284	TPM_LEPSA Tropomyosin OS=Lepisma saccharina (...	152	0.014	38.5	26	52
31	Q07068	284	TPM1_CIOIN Tropomyosin, smooth muscle/fibrobl...	157	0.28	34.7	31	44

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