Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL138C
Length:
161
Number of sequences:
5887
Description:
YIL138C TPM2 SGDID:S000001400, Chr IX from 89715-89230, Genome Release 64-1-1, reverse complement, Verified ORF, "Minor isoform of tropomyosin, binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; appears to have distinct and also overlapping functions with Tpm1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q03025    432   APRE_PSEAE Alkaline protease secretion protei...1040.74     33.5     32     44GO:0009276; C:Gram-negative-bacterium-type cell wall; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0009306; P:protein secretion; IEA:InterPro.::GO:0055085; P:transmembrane transport; IEA:InterPro.
92Q3UW12    575   CNGA4_MOUSE Cyclic nucleotide-gated cation ch...1110.74     33.5     25     43
GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007608; P:sensory perception of smell; IMP:MGI.
93Q6IRU2    248   TPM4_MOUSE Tropomyosin alpha-4 chain OS=Mus m...1650.76     33.1     25     56GO:0030863; C:cortical cytoskeleton; IDA:MGI.::GO:0002102; C:podosome; IDA:MGI.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
94Q0CQF3    639   SPB4_ASPTN ATP-dependent rRNA helicase spb4 O...880.79     33.5     30     49GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
95Q6PB44    1692   PTN23_MOUSE Tyrosine-protein phosphatase non-...1370.81     33.5     28     42GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
96P49455    518   TPM4_DROME Tropomyosin-1, isoforms 33/34 OS=D...1296     30.8     26     58GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030017; C:sarcomere; IDA:FlyBase.
GO:0003779; F:actin binding; TAS:FlyBase.
GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0006936; P:muscle contraction; NAS:FlyBase.::GO:0045451; P:pole plasm oskar mRNA localization; IMP:FlyBase.::GO:0010591; P:regulation of lamellipodium assembly; IMP:FlyBase.
97P02469    1786   LAMB1_MOUSE Laminin subunit beta-1 OS=Mus mus...1123     32     27     52GO:0005606; C:laminin-1 complex; IDA:MGI.::GO:0043259; C:laminin-10 complex; IPI:MGI.::GO:0005607; C:laminin-2 complex; ISS:HGNC.::GO:0043257; C:laminin-8 complex; ISS:HGNC.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0019899; F:enzyme binding; IPI:MGI.::GO:0005201; F:extracellular matrix structural constituent; ISS:HGNC.::GO:0043208; F:glycosphingolipid binding; IDA:MGI.::GO:0005178; F:integrin binding; IMP:MGI.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:MGI.::GO:0007566; P:embryo implantation; IMP:MGI.::GO:0007611; P:learning or memory; NAS:UniProtKB.::GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.::GO:0031175; P:neuron projection development; IDA:MGI.::GO:0042476; P:odontogenesis; ISS:HGNC.::GO:0030335; P:positive regulation of cell migration; ISS:HGNC.
98P09491    284   TPM2_DROME Tropomyosin-2 OS=Drosophila melano...1620.84     33.1     26     57
GO:0007507; P:heart development; IMP:FlyBase.
99Q9NFZ4    284   TPM_LEPDS Tropomyosin OS=Lepidoglyphus destru...1650.99     32.7     24     57
100P31816    283   TPM_LOCMI Tropomyosin OS=Locusta migratoria (...1651.1     32.7     24     58
101P07942    1786   LAMB1_HUMAN Laminin subunit beta-1 OS=Homo sa...1125.1     31.2     22     52GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0005606; C:laminin-1 complex; IDA:UniProtKB.::GO:0043259; C:laminin-10 complex; IDA:UniProtKB.::GO:0005607; C:laminin-2 complex; IDA:UniProtKB.::GO:0043257; C:laminin-8 complex; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0005201; F:extracellular matrix structural constituent; IDA:HGNC.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0042476; P:odontogenesis; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; TAS:HGNC.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL.
102Q8LE98    344   ICR1_ARATH Interactor of constitutive active ...841.3     32.7     36     60GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0090404; C:pollen tube tip; IDA:TAIR.
GO:2000012; P:regulation of auxin polar transport; IMP:TAIR.
103Q8TXI4    876   RAD50_METKA DNA double-strand break repair Ra...1911.3     32.7     29     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
104Q97BG8    613   DNAK_THEVO Chaperone protein DnaK OS=15438 / ...991.4     32.7     21     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
105Q5JDS2    663   VATI_PYRKO V-type ATP synthase subunit I OS=(...441.4     32.7     30     66GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
106Q8TDZ2    1067   MICA1_HUMAN Protein-methionine sulfoxide oxid...1451.4     32.7     26     47GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005882; C:intermediate filament; NAS:UniProtKB.
GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0071949; F:FAD binding; IDA:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030042; P:actin filament depolymerization; IDA:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.
107Q9BXX0    1053   EMIL2_HUMAN EMILIN-2 OS=Homo sapiens (Human)....1161.4     32.7     24     51GO:0005581; C:collagen; IEA:UniProtKB-KW.
GO:0030023; F:extracellular matrix constituent conferring elasticity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
108A1X157    1666   CTTB2_ECHTE Cortactin-binding protein 2 OS=Ec...1601.4     32.7     22     47
109Q26503    284   TPM_SCHHA Tropomyosin OS=Schistosoma haematob...1691.5     32.3     29     54
110F1MH07    1070   MICA1_BOVIN Protein-methionine sulfoxide oxid...1451.5     32.7     26     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0071949; F:FAD binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030042; P:actin filament depolymerization; ISS:UniProtKB.
111O75116    1388   ROCK2_HUMAN Rho-associated protein kinase 2 O...921.5     32.7     33     57GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005198; F:structural molecule activity; NAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051298; P:centrosome duplication; IMP:UniProtKB.::GO:0000910; P:cytokinesis; NAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; TAS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; TAS:UniProtKB.::GO:0045616; P:regulation of keratinocyte differentiation; IMP:UniProtKB.::GO:0051492; P:regulation of stress fiber assembly; TAS:UniProtKB.::GO:0006939; P:smooth muscle contraction; TAS:UniProtKB.
112Q8C0G2    513   T3JAM_MOUSE TRAF3-interacting JNK-activating ...901.6     32.3     30     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
113P08964    1928   MYO1_YEAST Myosin-1 OS=Saccharomyces cerevisi...941.6     32.7     35     55GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; ISS:SGD.
GO:0000916; P:contractile ring contraction involved in cell cycle cytokinesis; IMP:SGD.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:SGD.::GO:0007109; P:cytokinesis, completion of separation; IMP:SGD.
114Q9UI47    895   CTNA3_HUMAN Catenin alpha-3 OS=Homo sapiens (...851.7     32.3     28     51GO:0015629; C:actin cytoskeleton; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005916; C:fascia adherens; IDA:UniProtKB.
GO:0045296; F:cadherin binding; TAS:UniProtKB.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0016337; P:cell-cell adhesion; IPI:UniProtKB.
115Q6PKC3    985   TXD11_HUMAN Thioredoxin domain-containing pro...1038.4     30.4     26     54GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
116Q6A078    2472   CE290_MOUSE Centrosomal protein of 290 kDa OS...1451.8     32.3     31     51GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:HGNC.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:HGNC.::GO:0032391; C:photoreceptor connecting cilium; IDA:UniProtKB.::GO:0036038; C:TCTN-B9D complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0042462; P:eye photoreceptor cell development; ISS:HGNC.::GO:0030902; P:hindbrain development; ISS:HGNC.::GO:0030916; P:otic vesicle formation; ISS:HGNC.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:HGNC.::GO:0048793; P:pronephros development; ISS:HGNC.::GO:0015031; P:protein transport; IMP:UniProtKB.::GO:0060041; P:retina development in camera-type eye; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
117P10587    1979   MYH11_CHICK Myosin-11 OS=Gallus gallus (Chick...1641.9     32.3     30     52GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; ISS:UniProtKB.
GO:0048739; P:cardiac muscle fiber development; ISS:UniProtKB.::GO:0048251; P:elastic fiber assembly; ISS:UniProtKB.::GO:0030241; P:skeletal muscle myosin thick filament assembly; ISS:UniProtKB.::GO:0006939; P:smooth muscle contraction; ISS:UniProtKB.
118Q62261    2363   SPTB2_MOUSE Spectrin beta chain, brain 1 OS=M...1112.1     32.3     29     49GO:0032437; C:cuticular plate; IDA:MGI.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0008091; C:spectrin; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007182; P:common-partner SMAD protein phosphorylation; IDA:MGI.::GO:0007184; P:SMAD protein import into nucleus; IDA:MGI.
119Q01082    2364   SPTB2_HUMAN Spectrin beta chain, brain 1 OS=H...1112.2     32.3     29     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HGNC.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008091; C:spectrin; TAS:ProtInc.
GO:0003779; F:actin binding; TAS:ProtInc.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.
120P42637    284   TPM1_SCHMA Tropomyosin-1 OS=Schistosoma manso...1692.3     32     29     54
121P50023    613   DNAK_THEAC Chaperone protein DnaK OS=NBRC 151...1152.4     32     23     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
records
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