Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL138C
Length:
161
Number of sequences:
5887
Description:
YIL138C TPM2 SGDID:S000001400, Chr IX from 89715-89230, Genome Release 64-1-1, reverse complement, Verified ORF, "Minor isoform of tropomyosin, binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; appears to have distinct and also overlapping functions with Tpm1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121P50023    613   DNAK_THEAC Chaperone protein DnaK OS=NBRC 151...1152.4     32     23     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.
122A6NNT2    1141   CP096_HUMAN Putative uncharacterized protein ...1472.5     32     22     45
123P25391    3075   LAMA1_HUMAN Laminin subunit alpha-1 OS=Homo s...1342.7     32     20     49GO:0005615; C:extracellular space; IDA:UniProtKB.::GO:0005606; C:laminin-1 complex; IDA:UniProtKB.::GO:0005608; C:laminin-3 complex; IPI:UniProtKB.
GO:0005201; F:extracellular matrix structural constituent; ISS:UniProtKB.::GO:0005102; F:receptor binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007166; P:cell surface receptor signaling pathway; ISS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.
124P85001    2439   CE290_DANRE Centrosomal protein of 290 kDa OS...1413     32     28     53GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0021549; P:cerebellum development; IMP:ZFIN.::GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.::GO:0042462; P:eye photoreceptor cell development; IMP:HGNC.::GO:0030916; P:otic vesicle formation; IMP:HGNC.::GO:0048793; P:pronephros development; IMP:HGNC.::GO:0015031; P:protein transport; ISS:UniProtKB.
125Q9GZ71    284   TPM_HALDV Tropomyosin OS=Haliotis diversicolo...1693.1     31.6     26     54
126Q62839    998   GOGA2_RAT Golgin subfamily A member 2 OS=Ratt...1483.1     31.6     27     49GO:0005801; C:cis-Golgi network; IDA:MGI.::GO:0000137; C:Golgi cis cisterna; IDA:RGD.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0032403; F:protein complex binding; IDA:RGD.
127Q5PQX0    420   UXS1_RAT UDP-glucuronic acid decarboxylase 1 ...753.2     31.6     25     55GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0048040; F:UDP-glucuronate decarboxylase activity; IDA:RGD.
GO:0044237; P:cellular metabolic process; IEA:InterPro.
128O88902    1499   PTN23_RAT Tyrosine-protein phosphatase non-re...1373.5     31.6     27     42GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
129Q2KIW6    389   PRS10_BOVIN 26S protease regulatory subunit 1...663.6     31.2     36     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
130Q96NL6    688   SCLT1_HUMAN Sodium channel and clathrin linke...1323.6     31.6     27     51GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.
131Q9P219    2028   DAPLE_HUMAN Protein Daple OS=Homo sapiens (Hu...613.7     31.6     34     59GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005626; C:insoluble fraction; ISS:UniProtKB.
GO:0008017; F:microtubule binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0043621; F:protein self-association; ISS:UniProtKB.
GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0001932; P:regulation of protein phosphorylation; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
132O29106    676   VATI_ARCFU V-type ATP synthase subunit I OS=9...475.1     31.2     30     68GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0033177; C:proton-transporting two-sector ATPase complex, proton-transporting domain; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.::GO:0004828; F:serine-tRNA ligase activity; IEA:InterPro.
GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
133P62335    389   PRS10_SPETR 26S protease regulatory subunit 1...663.9     31.2     36     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
134P62334    389   PRS10_MOUSE 26S protease regulatory subunit 1...663.9     31.2     36     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
135P62333    389   PRS10_HUMAN 26S protease regulatory subunit 1...663.9     31.2     36     59GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:UniProtKB.::GO:0030674; F:protein binding, bridging; NAS:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
136Q66HB6    847   CAGE1_RAT Cancer-associated gene 1 protein ho...953.9     31.2     28     56
137Q05870    866   MYSP_SCHJA Paramyosin OS=Schistosoma japonicu...1663.9     31.2     27     48GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
GO:0003774; F:motor activity; IEA:InterPro.
138Q13751    1172   LAMB3_HUMAN Laminin subunit beta-3 OS=Homo sa...1338.1     30.4     20     47
GO:0005198; F:structural molecule activity; NAS:ProtInc.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0008544; P:epidermis development; TAS:ProtInc.::GO:0031581; P:hemidesmosome assembly; TAS:Reactome.
139Q5IR70    849   CAGE1_MOUSE Cancer-associated gene 1 protein ...804.1     31.2     31     58
140Q7S304    707   BRE1_NEUCR E3 ubiquitin-protein ligase bre-1 ...1234.2     31.2     32     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
141P05659    1509   MYSN_ACACA Myosin-2 heavy chain, non muscle O...914.4     31.2     33     54GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
142Q21313    3672   EPI1_CAEEL Laminin-like protein epi-1 OS=Caen...1414.6     31.2     20     48GO:0005604; C:basement membrane; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:InterPro.
143Q6VGS5    2009   DAPLE_MOUSE Protein Daple OS=Mus musculus (Mo...615.2     31.2     34     59GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005626; C:insoluble fraction; IDA:UniProtKB.
GO:0008017; F:microtubule binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; IPI:UniProtKB.::GO:0043621; F:protein self-association; IPI:UniProtKB.
GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0051260; P:protein homooligomerization; IPI:UniProtKB.::GO:0001932; P:regulation of protein phosphorylation; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
144Q9NDS0    284   TPM_BRABE Tropomyosin OS=Branchiostoma belche...1626.9     30.4     27     53
145O16127    278   TPM_ECHGR Tropomyosin A OS=Echinococcus granu...1627     30.4     24     51
146Q9UTJ8    1285   RAD50_SCHPO DNA repair protein rad50 OS=Schiz...887.3     30.4     32     50GO:0030870; C:Mre11 complex; TAS:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; TAS:PomBase.::GO:0003677; F:DNA binding; TAS:PomBase.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000724; P:double-strand break repair via homologous recombination; IGI:PomBase.::GO:0000734; P:gene conversion at mating-type locus, DNA repair synthesis; IMP:PomBase.::GO:0031573; P:intra-S DNA damage checkpoint; TAS:PomBase.::GO:0042138; P:meiotic DNA double-strand break formation; IMP:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.::GO:0000723; P:telomere maintenance; IMP:PomBase.
147Q8VDP3    1048   MICA1_MOUSE Protein-methionine sulfoxide oxid...1387.4     30.4     24     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0071949; F:FAD binding; ISS:UniProtKB.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030042; P:actin filament depolymerization; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:UniProtKB.
148Q9HLR8    896   RAD50_THEAC DNA double-strand break repair Ra...1037.6     30.4     32     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
149Q8BW94    4083   DYH3_MOUSE Dynein heavy chain 3, axonemal OS=...837.6     30.4     36     51GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003777; F:microtubule motor activity; IEA:InterPro.
GO:0007018; P:microtubule-based movement; IEA:InterPro.
150P85120    2058   DAPLE_XENLA Daple-like protein OS=Xenopus lae...617.8     30.4     31     59GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005626; C:insoluble fraction; ISS:UniProtKB.
GO:0008017; F:microtubule binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.
GO:0007257; P:activation of JUN kinase activity; IMP:UniProtKB.::GO:0060070; P:canonical Wnt receptor signaling pathway; IGI:UniProtKB.::GO:0009950; P:dorsal/ventral axis specification; IMP:UniProtKB.::GO:0001736; P:establishment of planar polarity; IMP:UniProtKB.::GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.::GO:0060071; P:Wnt receptor signaling pathway, planar cell polarity pathway; IMP:UniProtKB.
151Q99816    390   TS101_HUMAN Tumor susceptibility gene 101 pro...637.8     30.4     33     63GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005771; C:multivesicular body; TAS:HGNC.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0043130; F:ubiquitin binding; TAS:HGNC.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0046788; P:egress of virus within host cell; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0046755; P:non-lytic virus budding; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IDA:HGNC.
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