UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YIL137C

Length:

946

Number of sequences:

5887

Description:

YIL137C TMA108 SGDID:S000001399, Chr IX from 92788-89948, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein that associates with ribosomes and is involved in ribosome biogenesis; putative metalloprotease"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P40462	946	TM108_YEAST Protein TMA108 OS=Saccharomyces c...	946	0	1959	100	100	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0042254; P:ribosome biogenesis; IMP:SGD.
2	P95928	785	APE2_SULSO Leucyl aminopeptidase OS=P2). GN=a...	537	8e-51	195	28	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
3	Q59KZ1	924	APE2_CANAL Aminopeptidase 2 OS=Candida albica...	582	3e-50	195	27	46	GO:0005576; C:extracellular region; IDA:CGD.::GO:0009277; C:fungal-type cell wall; IDA:CGD.::GO:0005622; C:intracellular; IDA:CGD.
									GO:0070006; F:metalloaminopeptidase activity; IDA:CGD.::GO:0008236; F:serine-type peptidase activity; IDA:CGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
4	P37898	856	AAP1_YEAST Alanine/arginine aminopeptidase OS...	814	7e-50	193	24	44	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0005977; P:glycogen metabolic process; IMP:SGD.::GO:0006508; P:proteolysis; IMP:SGD.
5	Q9USX1	882	APE1_SCHPO Aminopeptidase 1 OS=Schizosaccharo...	584	7e-49	191	28	47	GO:0005829; C:cytosol; IDA:PomBase.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0044248; P:cellular catabolic process; NAS:PomBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
6	P32454	952	APE2_YEAST Aminopeptidase 2, mitochondrial OS...	586	2e-48	190	27	46	GO:0030287; C:cell wall-bounded periplasmic space; IDA:SGD.::GO:0005576; C:extracellular region; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
									GO:0070006; F:metalloaminopeptidase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0043171; P:peptide catabolic process; IDA:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
7	Q97AJ6	779	TRF3_THEVO Tricorn protease-interacting facto...	485	3e-47	185	28	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
8	Q11011	920	PSA_MOUSE Puromycin-sensitive aminopeptidase ...	586	6e-46	182	26	46	GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
9	P55786	919	PSA_HUMAN Puromycin-sensitive aminopeptidase ...	586	7e-46	182	26	46	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; TAS:ProtInc.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.::GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
10	O93655	780	TRF3_THEAC Tricorn protease-interacting facto...	472	3e-45	178	27	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
11	Q8SRG3	864	AMP12_ENCCU Probable M1 family aminopeptidase...	717	5e-44	176	24	43
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
12	Q96ZT9	786	APE1_SULTO Probable aminopeptidase 1 OS=Sulfo...	439	7e-44	174	29	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
13	P97629	1025	LCAP_RAT Leucyl-cystinyl aminopeptidase OS=Ra...	599	7e-44	176	28	46	GO:0009986; C:cell surface; IDA:RGD.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0032593; C:insulin-responsive compartment; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.
									GO:0004177; F:aminopeptidase activity; IDA:RGD.::GO:0001595; F:angiotensin receptor activity; IMP:RGD.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0017046; F:peptide hormone binding; IMP:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0010813; P:neuropeptide catabolic process; IMP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:RGD.::GO:0009725; P:response to hormone stimulus; IDA:RGD.
14	Q9UIQ6	1025	LCAP_HUMAN Leucyl-cystinyl aminopeptidase OS=...	691	2e-43	174	26	46	GO:0005829; C:cytosol; TAS:Reactome.::GO:0031905; C:early endosome lumen; TAS:Reactome.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
									GO:0004177; F:aminopeptidase activity; TAS:HGNC.::GO:0008237; F:metallopeptidase activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
									GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.::GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007565; P:female pregnancy; TAS:ProtInc.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0006508; P:proteolysis; TAS:ProtInc.
15	Q8SQI6	864	AMP11_ENCCU Probable M1 family aminopeptidase...	717	3e-43	173	24	42
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
16	Q978U3	783	TRF2_THEVO Tricorn protease-interacting facto...	476	3e-42	169	26	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
17	Q8C129	1025	LCAP_MOUSE Leucyl-cystinyl aminopeptidase OS=...	603	5e-42	170	27	46	GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
									GO:0004177; F:aminopeptidase activity; IMP:MGI.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030163; P:protein catabolic process; IMP:MGI.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
18	O57579	967	AMPN_CHICK Aminopeptidase N OS=Gallus gallus ...	660	2e-41	168	26	41	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
19	O93654	783	TRF2_THEAC Tricorn protease-interacting facto...	469	3e-41	166	26	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
20	Q974N6	781	APE2_SULTO Probable aminopeptidase 2 OS=Sulfo...	473	7e-41	165	25	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
21	P50123	945	AMPE_RAT Glutamyl aminopeptidase OS=Rattus no...	521	1e-40	166	27	46	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0031983; C:vesicle lumen; IDA:RGD.::GO:0012506; C:vesicle membrane; IDA:RGD.
									GO:0070006; F:metalloaminopeptidase activity; ISS:UniProtKB.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006725; P:cellular aromatic compound metabolic process; IDA:RGD.::GO:0006508; P:proteolysis; IDA:RGD.::GO:0003081; P:regulation of systemic arterial blood pressure by renin-angiotensin; ISS:UniProtKB.
22	Q97VF1	784	APE1_SULSO Probable aminopeptidase 1 OS=P2). ...	528	5e-40	163	26	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
23	Q10836	1025	TRHDE_RAT Thyrotropin-releasing hormone-degra...	643	8e-40	163	25	43	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004177; F:aminopeptidase activity; TAS:RGD.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; TAS:RGD.
24	Q8K093	1025	TRHDE_MOUSE Thyrotropin-releasing hormone-deg...	643	2e-39	162	25	43	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
25	P16406	945	AMPE_MOUSE Glutamyl aminopeptidase OS=Mus mus...	499	6e-39	160	27	43	GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005903; C:brush border; IDA:MGI.::GO:0031410; C:cytoplasmic vesicle; IDA:MGI.::GO:0009897; C:external side of plasma membrane; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0070006; F:metalloaminopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0001525; P:angiogenesis; IMP:MGI.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0032835; P:glomerulus development; IEP:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0003081; P:regulation of systemic arterial blood pressure by renin-angiotensin; ISS:UniProtKB.
26	Q9UKU6	1024	TRHDE_HUMAN Thyrotropin-releasing hormone-deg...	618	4e-38	158	26	43	GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
									GO:0004177; F:aminopeptidase activity; TAS:ProtInc.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.
27	Q32LQ0	956	AMPE_BOVIN Glutamyl aminopeptidase OS=Bos tau...	462	6e-38	157	27	47	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0070006; F:metalloaminopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0003081; P:regulation of systemic arterial blood pressure by renin-angiotensin; ISS:UniProtKB.
28	A6QPT7	954	ERAP2_BOVIN Endoplasmic reticulum aminopeptid...	632	8e-38	157	25	43	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
29	Q95334	942	AMPE_PIG Glutamyl aminopeptidase OS=Sus scrof...	369	1e-37	156	29	49	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0070006; F:metalloaminopeptidase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0003081; P:regulation of systemic arterial blood pressure by renin-angiotensin; ISS:UniProtKB.
30	Q07075	957	AMPE_HUMAN Glutamyl aminopeptidase OS=Homo sa...	492	1e-37	156	28	45	GO:0016324; C:apical plasma membrane; ISS:UniProtKB.::GO:0005903; C:brush border; ISS:UniProtKB.::GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0009897; C:external side of plasma membrane; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.
									GO:0070006; F:metalloaminopeptidase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0002005; P:angiotensin catabolic process in blood; NAS:UniProtKB.::GO:0016477; P:cell migration; IDA:MGI.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0007267; P:cell-cell signaling; NAS:UniProtKB.::GO:0032835; P:glomerulus development; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
31	P37896	843	AMPN_LACDL Aminopeptidase N OS=Lactobacillus ...	511	2e-37	155	26	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.

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