UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YIL137C

Length:

946

Number of sequences:

5887

Description:

YIL137C TMA108 SGDID:S000001399, Chr IX from 92788-89948, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein that associates with ribosomes and is involved in ribosome biogenesis; putative metalloprotease"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	P37896	843	AMPN_LACDL Aminopeptidase N OS=Lactobacillus ...	511	2e-37	155	26	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
32	P15144	967	AMPN_HUMAN Aminopeptidase N OS=Homo sapiens (...	737	5e-37	154	23	44	GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
									GO:0004177; F:aminopeptidase activity; TAS:ProtInc.::GO:0008237; F:metallopeptidase activity; TAS:ProtInc.::GO:0004872; F:receptor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
33	Q9CIQ1	846	AMPN_LACLA Aminopeptidase N OS=lactis). GN=pe...	748	2e-36	152	26	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
34	P79098	965	AMPN_BOVIN Aminopeptidase N OS=Bos taurus (Bo...	766	2e-36	152	24	42	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
35	Q48656	849	AMPN_LACLL Aminopeptidase N OS=Lactococcus la...	541	2e-36	152	27	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
36	Q5RFP3	960	ERAP2_PONAB Endoplasmic reticulum aminopeptid...	648	4e-36	151	26	43	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
37	Q6P179	960	ERAP2_HUMAN Endoplasmic reticulum aminopeptid...	821	5e-36	151	24	42	GO:0005788; C:endoplasmic reticulum lumen; TAS:HGNC.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004177; F:aminopeptidase activity; IDA:HGNC.::GO:0008237; F:metallopeptidase activity; IDA:HGNC.::GO:0008270; F:zinc ion binding; TAS:HGNC.
									GO:0019885; P:antigen processing and presentation of endogenous peptide antigen via MHC class I; TAS:HGNC.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0008217; P:regulation of blood pressure; TAS:HGNC.
38	Q10730	844	AMPN_LACHE Aminopeptidase N OS=Lactobacillus ...	533	1e-35	149	26	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
39	P15541	966	AMPN_RABIT Aminopeptidase N OS=Oryctolagus cu...	477	2e-35	149	27	45	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
40	P15145	963	AMPN_PIG Aminopeptidase N OS=Sus scrofa (Pig)...	748	3e-34	145	23	42	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
41	A6NEC2	478	PSAL_HUMAN Puromycin-sensitive aminopeptidase...	338	4e-34	141	28	48
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
42	Q10737	972	AMPN_HAECO Aminopeptidase N OS=Haemonchus con...	507	1e-33	143	26	44	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
43	Q10736	355	AMPN_ACEPA Aminopeptidase N OS=Acetobacter pa...	253	2e-33	137	34	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
44	Q6Q4G3	990	AMPQ_HUMAN Aminopeptidase Q OS=Homo sapiens (...	534	3e-33	142	26	43	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
45	P0C2T8	846	AMPN_LACLC Aminopeptidase N OS=Lactococcus la...	751	3e-33	142	25	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
46	A2RI32	846	AMPN_LACLM Aminopeptidase N OS=Lactococcus la...	751	3e-33	141	25	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
47	P79171	967	AMPN_FELCA Aminopeptidase N OS=Felis catus (C...	639	2e-32	139	24	41	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
48	P15684	965	AMPN_RAT Aminopeptidase N OS=Rattus norvegicu...	474	7e-32	137	26	45	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0031983; C:vesicle lumen; IDA:RGD.::GO:0012506; C:vesicle membrane; IDA:RGD.
									GO:0004177; F:aminopeptidase activity; IDA:RGD.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006725; P:cellular aromatic compound metabolic process; IDA:RGD.::GO:0035814; P:negative regulation of renal sodium excretion; IMP:RGD.::GO:0006508; P:proteolysis; IDA:RGD.
49	P91887	946	AMPN_PLUXY Aminopeptidase N OS=Plutella xylos...	784	3e-31	135	22	40	GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
50	Q9JJ22	930	ERAP1_RAT Endoplasmic reticulum aminopeptidas...	533	4e-31	135	24	41	GO:0005788; C:endoplasmic reticulum lumen; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.
									GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0005138; F:interleukin-6 receptor binding; ISS:UniProtKB.::GO:0008235; F:metalloexopeptidase activity; ISS:UniProtKB.::GO:0005164; F:tumor necrosis factor receptor binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IMP:RGD.
									GO:0019882; P:antigen processing and presentation; TAS:RGD.::GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.
51	Q9NZ08	941	ERAP1_HUMAN Endoplasmic reticulum aminopeptid...	622	9e-31	134	24	40	GO:0005829; C:cytosol; NAS:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; TAS:HGNC.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IDA:UniProtKB.::GO:0016021; C:integral to membrane; NAS:UniProtKB.
									GO:0004177; F:aminopeptidase activity; IDA:UniProtKB.::GO:0005151; F:interleukin-1, Type II receptor binding; TAS:HGNC.::GO:0005138; F:interleukin-6 receptor binding; IPI:UniProtKB.::GO:0008235; F:metalloexopeptidase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
									GO:0001525; P:angiogenesis; TAS:HGNC.::GO:0019885; P:antigen processing and presentation of endogenous peptide antigen via MHC class I; NAS:UniProtKB.::GO:0045444; P:fat cell differentiation; NAS:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.::GO:0008217; P:regulation of blood pressure; NAS:UniProtKB.::GO:0045088; P:regulation of innate immune response; NAS:UniProtKB.::GO:0009617; P:response to bacterium; IEP:BHF-UCL.
52	Q9EQH2	930	ERAP1_MOUSE Endoplasmic reticulum aminopeptid...	402	6e-30	131	25	45	GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0005138; F:interleukin-6 receptor binding; ISS:UniProtKB.::GO:0008235; F:metalloexopeptidase activity; ISS:UniProtKB.
									GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; IMP:MGI.
53	Q11001	990	AMPM_MANSE Membrane alanyl aminopeptidase OS=...	675	8e-30	131	22	41	GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
54	P91885	942	AMPN_MANSE Aminopeptidase N OS=Manduca sexta ...	614	1e-28	127	24	41	GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
55	Q2KHK3	559	AMPQ_MOUSE Aminopeptidase Q OS=Mus musculus (...	486	7e-28	123	26	42	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
56	P97449	966	AMPN_MOUSE Aminopeptidase N OS=Mus musculus (...	385	3e-27	123	25	43	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
57	Q11000	1009	AMPM_HELVI Membrane alanyl aminopeptidase OS=...	636	2e-24	114	22	39	GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
58	Q11010	857	AMPN_STRLI Aminopeptidase N OS=Streptomyces l...	361	7e-19	95.9	23	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
59	A2QKF8	618	LKHA4_ASPNC Leukotriene A-4 hydrolase homolog...	328	0.00000000002	71.2	26	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; IEA:EC.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0019370; P:leukotriene biosynthetic process; IEA:UniProtKB-KW.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
60	P52922	606	LKHA4_DICDI Leukotriene A-4 hydrolase homolog...	425	0.00000000003	70.9	22	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; IEA:EC.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0019370; P:leukotriene biosynthetic process; IEA:UniProtKB-KW.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
61	Q7S785	614	LKHA4_NEUCR Leukotriene A-4 hydrolase homolog...	305	0.00000000004	70.5	26	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.::GO:0004301; F:epoxide hydrolase activity; ISS:UniProtKB.::GO:0004463; F:leukotriene-A4 hydrolase activity; IEA:EC.::GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0019370; P:leukotriene biosynthetic process; IEA:UniProtKB-KW.::GO:0043171; P:peptide catabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.

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