Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL131C
Length:
484
Number of sequences:
5887
Description:
YIL131C FKH1 SGDID:S000001393, Chr IX from 102235-100781, Genome Release 64-1-1, reverse complement, Verified ORF, "Forkhead family transcription factor with a minor role in the expression of G2/M phase genes; negatively regulates transcriptional elongation; positive role in chromatin silencing at HML and HMR; regulates donor preference during switching"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q3BJS1    506   FOXN4_XENLA Forkhead box protein N4 OS=Xenopu...1321e-16     85.9     36     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
122Q02361    456   FD3_DROME Fork head domain-containing protein...1062e-16     85.5     39     56GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0048484; P:enteric nervous system development; IBA:RefGenome.::GO:0048937; P:lateral line nerve glial cell development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0007422; P:peripheral nervous system development; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0048485; P:sympathetic nervous system development; IBA:RefGenome.::GO:0035121; P:tail morphogenesis; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
123P42128    719   FOXK1_MOUSE Forkhead box protein K1 OS=Mus mu...860.036     40.4     24     55GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0000287; F:magnesium ion binding; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
124Q07342    409   FOXA2_DANRE Forkhead box protein A2 OS=Danio ...892e-16     84.7     44     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0019904; F:protein domain specific binding; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
125P35583    459   FOXA2_MOUSE Hepatocyte nuclear factor 3-beta ...1522e-16     85.1     35     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0007596; P:blood coagulation; IBA:RefGenome.::GO:0021533; P:cell differentiation in hindbrain; IMP:MGI.::GO:0032289; P:central nervous system myelin formation; IBA:RefGenome.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0071542; P:dopaminergic neuron differentiation; IMP:MGI.::GO:0021904; P:dorsal/ventral neural tube patterning; IDA:MGI.::GO:0001705; P:ectoderm formation; IGI:MGI.::GO:0031018; P:endocrine pancreas development; IMP:MGI.::GO:0007492; P:endoderm development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IGI:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0060487; P:lung epithelial cell differentiation; IGI:MGI.::GO:2000971; P:negative regulation of detection of glucose; IDA:BHF-UCL.::GO:0033132; P:negative regulation of glucokinase activity; IDA:BHF-UCL.::GO:0045665; P:negative regulation of neuron differentiation; IGI:MGI.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IDA:BHF-UCL.::GO:0048665; P:neuron fate specification; IMP:MGI.::GO:0021779; P:oligodendrocyte cell fate commitment; IBA:RefGenome.::GO:0040019; P:positive regulation of embryonic development; IMP:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; IMP:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IMP:MGI.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IDA:BHF-UCL.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:UniProtKB.::GO:0090009; P:primitive streak formation; IMP:UniProtKB.::GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IDA:BHF-UCL.::GO:2000976; P:regulation of transcription from RNA polymerase II promoter involved in detection of glucose; IDA:BHF-UCL.::GO:0070741; P:response to interleukin-6; TAS:UniProtKB.::GO:0023019; P:signal transduction involved in regulation of gene expression; IDA:MGI.::GO:0032525; P:somite rostral/caudal axis specification; IMP:MGI.
126Q91765    434   FXA2A_XENLA Forkhead box protein A2-A OS=Xeno...892e-16     84.7     44     63GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0019904; F:protein domain specific binding; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0001707; P:mesoderm formation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
127Q7T1R4    434   FOXA2_XENTR Forkhead box protein A2 OS=Xenopu...892e-16     84.7     44     63GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0009952; P:anterior/posterior pattern specification; IBA:RefGenome.::GO:0007596; P:blood coagulation; IBA:RefGenome.::GO:0021533; P:cell differentiation in hindbrain; IBA:RefGenome.::GO:0032289; P:central nervous system myelin formation; IBA:RefGenome.::GO:0021904; P:dorsal/ventral neural tube patterning; IBA:RefGenome.::GO:0001705; P:ectoderm formation; IBA:RefGenome.::GO:0031018; P:endocrine pancreas development; IBA:RefGenome.::GO:0007492; P:endoderm development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IBA:RefGenome.::GO:0060487; P:lung epithelial cell differentiation; IBA:RefGenome.::GO:0001707; P:mesoderm formation; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; IBA:RefGenome.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0021779; P:oligodendrocyte cell fate commitment; IBA:RefGenome.::GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
128P85037    733   FOXK1_HUMAN Forkhead box protein K1 OS=Homo s...860.046     40     24     55GO:0005730; C:nucleolus; IDA:HPA.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0000287; F:magnesium ion binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
129P84961    433   FXA2B_XENLA Forkhead box protein A2-B OS=Xeno...893e-16     84.3     43     63GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0019904; F:protein domain specific binding; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0001707; P:mesoderm formation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
130O43058    663   SEP1_SCHPO Forkhead protein sep1 OS=Schizosac...953e-16     85.1     44     62GO:0005667; C:transcription factor complex; IC:PomBase.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; TAS:PomBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010590; P:regulation of cytokinetic cell separation; IMP:PomBase.::GO:0045896; P:regulation of transcription during mitosis; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
131Q96NZ1    517   FOXN4_HUMAN Forkhead box protein N4 OS=Homo s...1294e-16     84.7     34     57GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0048675; P:axon extension; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0048513; P:organ development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0008016; P:regulation of heart contraction; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
132Q9Y261    457   FOXA2_HUMAN Hepatocyte nuclear factor 3-beta ...894e-16     84.3     44     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0021533; P:cell differentiation in hindbrain; IBA:RefGenome.::GO:0032289; P:central nervous system myelin formation; IBA:RefGenome.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0021904; P:dorsal/ventral neural tube patterning; IBA:RefGenome.::GO:0001705; P:ectoderm formation; IBA:RefGenome.::GO:0031018; P:endocrine pancreas development; IDA:BHF-UCL.::GO:0007492; P:endoderm development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IBA:RefGenome.::GO:0001701; P:in utero embryonic development; IBA:RefGenome.::GO:0060487; P:lung epithelial cell differentiation; IBA:RefGenome.::GO:2000971; P:negative regulation of detection of glucose; ISS:BHF-UCL.::GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.::GO:0033132; P:negative regulation of glucokinase activity; ISS:BHF-UCL.::GO:0045665; P:negative regulation of neuron differentiation; IBA:RefGenome.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; ISS:BHF-UCL.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0021779; P:oligodendrocyte cell fate commitment; IBA:RefGenome.::GO:2000049; P:positive regulation of cell-cell adhesion mediated by cadherin; IC:BHF-UCL.::GO:0040019; P:positive regulation of embryonic development; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.::GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; ISS:BHF-UCL.::GO:0090009; P:primitive streak formation; ISS:UniProtKB.::GO:0030193; P:regulation of blood coagulation; IDA:UniProtKB.::GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:BHF-UCL.::GO:2000976; P:regulation of transcription from RNA polymerase II promoter involved in detection of glucose; ISS:BHF-UCL.::GO:0070741; P:response to interleukin-6; TAS:UniProtKB.
133Q5J3Q5    379   FOXE1_XENLA Forkhead box protein E1 OS=Xenopu...854e-16     83.6     41     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
134O14270    743   FHL1_SCHPO Fork head transcription factor 1 O...1340.000000000002     73.6     31     51GO:0005634; C:nucleus; IDA:PomBase.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; TAS:PomBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
135P33205    399   FXA4A_XENLA Forkhead box protein A4-A OS=Xeno...1187e-16     83.2     36     56GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0019904; F:protein domain specific binding; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0009948; P:anterior/posterior axis specification; IMP:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030900; P:forebrain development; IMP:UniProtKB.::GO:0001707; P:mesoderm formation; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0001840; P:neural plate development; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
136Q8ITI5    318   FOXG1_MNELE Forkhead box protein G1 OS=Mnemio...1117e-16     82     42     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
137P33206    400   FXA4B_XENLA Forkhead box protein A4-B OS=Xeno...897e-16     82.8     44     61GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0019904; F:protein domain specific binding; IEA:InterPro.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
138Q6P839    399   FOXA4_XENTR Forkhead box protein A4 OS=Xenopu...897e-16     82.8     44     61GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0009790; P:embryo development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IBA:RefGenome.::GO:0042593; P:glucose homeostasis; IBA:RefGenome.::GO:0060487; P:lung epithelial cell differentiation; IBA:RefGenome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0010817; P:regulation of hormone levels; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
139P34683    237   LIN31_CAEEL Protein lin-31 OS=Caenorhabditis ...920.000000000000001     80.1     42     58GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:WormBase.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0009790; P:embryo development; IBA:RefGenome.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.::GO:0040025; P:vulval development; IMP:WormBase.
140O88470    375   FOXL2_MOUSE Forkhead box protein L2 OS=Mus mu...900.000000000000003     80.5     42     60GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; ISS:UniProtKB.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0030331; F:estrogen receptor binding; IPI:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:RefGenome.
GO:0060026; P:convergent extension; IBA:RefGenome.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; ISS:UniProtKB.::GO:0048048; P:embryonic eye morphogenesis; IMP:MGI.::GO:0002074; P:extraocular skeletal muscle development; ISS:UniProtKB.::GO:0019101; P:female somatic sex determination; IMP:MGI.::GO:0060014; P:granulosa cell differentiation; IMP:MGI.::GO:0006917; P:induction of apoptosis; IDA:MGI.::GO:0042703; P:menstruation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
141Q6VFT6    377   FOXL2_PIG Forkhead box protein L2 OS=Sus scro...900.000000000000004     80.5     42     60GO:0005634; C:nucleus; ISS:AgBase.
GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:AgBase.
GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; ISS:UniProtKB.::GO:0048048; P:embryonic eye morphogenesis; ISS:AgBase.::GO:0002074; P:extraocular skeletal muscle development; ISS:UniProtKB.::GO:0019101; P:female somatic sex determination; ISS:AgBase.::GO:0060014; P:granulosa cell differentiation; ISS:AgBase.::GO:0006917; P:induction of apoptosis; ISS:AgBase.::GO:0042703; P:menstruation; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:AgBase.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:AgBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
142P58012    376   FOXL2_HUMAN Forkhead box protein L2 OS=Homo s...900.000000000000005     80.1     42     60GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; IMP:UniProtKB.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0030331; F:estrogen receptor binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.
GO:0060026; P:convergent extension; IBA:RefGenome.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IMP:UniProtKB.::GO:0048048; P:embryonic eye morphogenesis; IBA:RefGenome.::GO:0002074; P:extraocular skeletal muscle development; IMP:UniProtKB.::GO:0019101; P:female somatic sex determination; IBA:RefGenome.::GO:0006917; P:induction of apoptosis; IBA:RefGenome.::GO:0042703; P:menstruation; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0001541; P:ovarian follicle development; IMP:UniProtKB.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
143Q4VUF1    373   FOXL2_ELLLU Forkhead box protein L2 OS=Ellobi...900.000000000000005     80.1     42     60GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; ISS:UniProtKB.::GO:0002074; P:extraocular skeletal muscle development; ISS:UniProtKB.::GO:0042703; P:menstruation; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
144Q6VFT7    377   FOXL2_BOVIN Forkhead box protein L2 OS=Bos ta...900.000000000000005     80.1     42     60GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; ISS:UniProtKB.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0030331; F:estrogen receptor binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:RefGenome.
GO:0060026; P:convergent extension; IBA:RefGenome.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; ISS:UniProtKB.::GO:0048048; P:embryonic eye morphogenesis; ISS:AgBase.::GO:0002074; P:extraocular skeletal muscle development; ISS:UniProtKB.::GO:0019101; P:female somatic sex determination; ISS:AgBase.::GO:0060014; P:granulosa cell differentiation; ISS:AgBase.::GO:0006917; P:induction of apoptosis; ISS:AgBase.::GO:0042703; P:menstruation; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:AgBase.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:AgBase.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
145Q8MIP2    377   FOXL2_CAPHI Forkhead box protein L2 OS=Capra ...900.000000000000005     80.1     42     60GO:0005634; C:nucleus; ISS:AgBase.
GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; ISS:UniProtKB.::GO:0048048; P:embryonic eye morphogenesis; ISS:AgBase.::GO:0008210; P:estrogen metabolic process; NAS:UniProtKB.::GO:0002074; P:extraocular skeletal muscle development; ISS:UniProtKB.::GO:0019101; P:female somatic sex determination; ISS:AgBase.::GO:0060014; P:granulosa cell differentiation; ISS:AgBase.::GO:0006917; P:induction of apoptosis; ISS:AgBase.::GO:0042703; P:menstruation; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; IEP:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:AgBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
146Q6VFT5    384   FOXL2_RABIT Forkhead box protein L2 OS=Orycto...900.000000000000006     80.1     42     60GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; ISS:UniProtKB.::GO:0002074; P:extraocular skeletal muscle development; ISS:UniProtKB.::GO:0042703; P:menstruation; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
147Q02360    365   FD2_DROME Fork head domain-containing protein...870.000000000000007     79.7     44     60GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0016199; P:axon midline choice point recognition; IBA:RefGenome.::GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0009792; P:embryo development ending in birth or egg hatching; IBA:RefGenome.::GO:0045665; P:negative regulation of neuron differentiation; IBA:RefGenome.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0035058; P:nonmotile primary cilium assembly; IBA:RefGenome.::GO:0045787; P:positive regulation of cell cycle; IBA:RefGenome.::GO:0002052; P:positive regulation of neuroblast proliferation; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007346; P:regulation of mitotic cell cycle; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0007380; P:specification of segmental identity, head; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.
148P25364    564   HCM1_YEAST Forkhead transcription factor HCM1...920.000000000000007     80.5     42     59GO:0005737; C:cytoplasm; IDA:SGD.::GO:0000790; C:nuclear chromatin; IDA:SGD.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0008134; F:transcription factor binding; IBA:RefGenome.
GO:0034599; P:cellular response to oxidative stress; IMP:SGD.::GO:0007005; P:mitochondrion organization; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.::GO:0090418; P:positive regulation of transcription involved in S-phase of mitotic cell cycle; IMP:SGD.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0051300; P:spindle pole body organization; IGI:SGD.
149P39521    936   FHL1_YEAST Pre-rRNA-processing protein FHL1 O...1240.00000000006     68.6     38     56GO:0000790; C:nuclear chromatin; IDA:SGD.::GO:0005730; C:nucleolus; IDA:SGD.::GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0070491; F:repressing transcription factor binding; IPI:SGD.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.
GO:0010688; P:negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter; IMP:SGD.::GO:0060963; P:positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter; IMP:SGD.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
150P55317    472   FOXA1_HUMAN Hepatocyte nuclear factor 3-alpha...890.00000000000001     79.7     42     61GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0006338; P:chromatin remodeling; ISS:UniProtKB.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0060743; P:epithelial cell maturation involved in prostate gland development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IBA:RefGenome.::GO:0060738; P:epithelial-mesenchymal signaling involved in prostate gland development; IBA:RefGenome.::GO:0042593; P:glucose homeostasis; IBA:RefGenome.::GO:0060487; P:lung epithelial cell differentiation; IBA:RefGenome.::GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.::GO:0008634; P:negative regulation of survival gene product expression; IDA:UniProtKB.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:2000049; P:positive regulation of cell-cell adhesion mediated by cadherin; IC:BHF-UCL.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IMP:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0060740; P:prostate gland epithelium morphogenesis; IBA:RefGenome.::GO:0060741; P:prostate gland stromal morphogenesis; IBA:RefGenome.::GO:0032355; P:response to estradiol stimulus; IDA:UniProtKB.::GO:0060528; P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; IBA:RefGenome.
151P23512    466   FOXA1_RAT Hepatocyte nuclear factor 3-alpha O...890.00000000000001     79.7     42     61GO:0005667; C:transcription factor complex; IBA:RefGenome.
GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IDA:RGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IPI:MGI.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0060743; P:epithelial cell maturation involved in prostate gland development; IBA:RefGenome.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IBA:RefGenome.::GO:0060738; P:epithelial-mesenchymal signaling involved in prostate gland development; IBA:RefGenome.::GO:0042593; P:glucose homeostasis; IBA:RefGenome.::GO:0060487; P:lung epithelial cell differentiation; IBA:RefGenome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0048665; P:neuron fate specification; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.::GO:0060740; P:prostate gland epithelium morphogenesis; IBA:RefGenome.::GO:0060741; P:prostate gland stromal morphogenesis; IBA:RefGenome.::GO:0010817; P:regulation of hormone levels; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0060528; P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; IBA:RefGenome.
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