Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL124W
Length:
297
Number of sequences:
5887
Description:
YIL124W AYR1 SGDID:S000001386, Chr IX from 126204-127097, Genome Release 64-1-1, Verified ORF, "NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles, ER, and mitochondrial outer membrane; involved in phosphatidic acid biosynthesis; required for spore germination; capable of metabolizing steroid hormones"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q8TC12    318   RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo ...1200.00000003     57.8     38     48GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0052650; F:NADP-retinol dehydrogenase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.
GO:0042574; P:retinal metabolic process; IDA:MGI.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:Reactome.
212Q6AYS8    298   DHB11_RAT Estradiol 17-beta-dehydrogenase 11 ...1750.00000003     57.8     30     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
213Q9RPT1    256   RHLG_PSEAE Rhamnolipids biosynthesis 3-oxoacy...2390.00000003     57     28     44
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.]
214Q9EQ06    298   DHB11_MOUSE Estradiol 17-beta-dehydrogenase 1...1750.00000003     57.4     30     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
215O14756    317   H17B6_HUMAN 17-beta-hydroxysteroid dehydrogen...1870.00000003     57.4     28     47GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC.
GO:0006702; P:androgen biosynthetic process; NAS:UniProtKB.::GO:0006710; P:androgen catabolic process; TAS:UniProtKB.
216Q68ER2    236   CBR4_XENTR Carbonyl reductase family member 4...2050.00000003     56.6     31     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
217P08694    275   BPHB_PSEPS Cis-2,3-dihydrobiphenyl-2,3-diol d...1150.00000004     57     36     55
GO:0018509; F:cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
218Q91X52    244   DCXR_MOUSE L-xylulose reductase OS=Mus muscul...1770.00000004     56.6     29     47GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005903; C:brush border; IDA:MGI.::GO:0005902; C:microvillus; IDA:MGI.
GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0006739; P:NADP metabolic process; IDA:MGI.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:MGI.
219P16544    261   ACT3_STRCO Putative ketoacyl reductase OS=Str...1910.00000004     57     25     43
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
220P52037    247   YGFF_ECOLI Uncharacterized oxidoreductase ygf...2610.00000004     56.6     28     41
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
221P16232    288   DHI1_RAT Corticosteroid 11-beta-dehydrogenase...2070.00000004     57     29     45GO:0045177; C:apical part of cell; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0031965; C:nuclear membrane; IDA:RGD.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD.
GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0050661; F:NADP binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD.
GO:0071392; P:cellular response to estradiol stimulus; IEP:RGD.::GO:0006704; P:glucocorticoid biosynthetic process; IDA:RGD.::GO:0006713; P:glucocorticoid catabolic process; IDA:RGD.::GO:0018963; P:phthalate metabolic process; IEP:RGD.::GO:0043456; P:regulation of pentose-phosphate shunt; IDA:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.]
222A8Q1U2    324   MKAR_MALGO 3-ketoacyl-CoA reductase OS=(Dandr...1780.00000004     57.4     29     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
223Q84ST4    343   NOL_ORYSJ Chlorophyll(ide) b reductase NOL, c...1940.00000004     57.4     26     45GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
GO:0034256; F:chlorophyll(ide) b reductase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0015996; P:chlorophyll catabolic process; IEA:UniProtKB-KW.
224Q1JP75    244   DCXR_BOVIN L-xylulose reductase OS=Bos taurus...1770.00000004     56.6     29     46GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0050038; F:L-xylulose reductase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
225P40580    263   BZRD_YEAST Benzil reductase ((S)-benzoin form...1950.00000005     56.6     28     45GO:0005737; C:cytoplasm; IDA:SGD.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:EC.
226P37694    287   HETN_NOSS1 Ketoacyl reductase hetN OS=Nostoc ...1760.00000006     56.6     26     43
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0043158; P:heterocyst differentiation; IEA:UniProtKB-KW.
227P0C0Y4    266   MTDH_ALTAL Probable NADP-dependent mannitol d...2260.00000006     56.2     27     46
GO:0050085; F:mannitol 2-dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
228P47727    277   CBR1_RAT Carbonyl reductase [NADPH] 1 OS=Ratt...1370.00000007     56.2     32     49GO:0005829; C:cytosol; TAS:RGD.::GO:0005792; C:microsome; IDA:RGD.::GO:0005902; C:microvillus; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.
GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC.
GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0001542; P:ovulation from ovarian follicle; IEP:RGD.::GO:0018205; P:peptidyl-lysine modification; NAS:RGD.::GO:0042376; P:phylloquinone catabolic process; IDA:RGD.::GO:0034698; P:response to gonadotropin stimulus; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.
229P50172    292   DHI1_MOUSE Corticosteroid 11-beta-dehydrogena...2000.00000008     56.2     28     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0030324; P:lung development; IMP:MGI.::GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.]
230Q6QA33    311   DH12B_DANRE Estradiol 17-beta-dehydrogenase 1...2070.00000008     56.2     27     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
231Q5RCF8    278   DHRS4_PONAB Dehydrogenase/reductase SDR famil...1800.00000009     56.2     27     49GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
232Q7TQA3    309   RDHE2_MOUSE Epidermal retinol dehydrogenase 2...1780.00000009     56.2     29     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC.
233Q8WNV7    279   DHRS4_PIG Dehydrogenase/reductase SDR family ...1770.00000009     55.8     27     49GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
234Q8BYK4    316   RDH12_MOUSE Retinol dehydrogenase 12 OS=Mus m...1190.0000001     56.2     36     48GO:0005622; C:intracellular; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
235O75828    277   CBR3_HUMAN Carbonyl reductase [NADPH] 3 OS=Ho...1520.0000001     55.8     32     47GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0070402; F:NADPH binding; IDA:UniProtKB.
236Q9KQH7    244   FABG_VIBCH 3-oxoacyl-[acyl-carrier-protein] r...1870.0000001     55.5     27     46
GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0050661; F:NADP binding; ISS:UniProtKB.
GO:0030497; P:fatty acid elongation; ISS:UniProtKB.]
237A7F8T1    334   MKAR_SCLS1 3-ketoacyl-CoA reductase OS=mold) ...1830.0000001     55.8     26     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
238P87218    280   SOU2_CANAL Sorbose reductase homolog SOU2 OS=...2170.0000001     55.5     29     49
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
239Q7Z4W1    244   DCXR_HUMAN L-xylulose reductase OS=Homo sapie...1760.0000001     55.1     29     45GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.
GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB.
240A8N6B4    339   MKAR_COPC7 3-ketoacyl-CoA reductase OS=9003) ...1980.0000001     55.5     29     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
241Q9BTZ2    278   DHRS4_HUMAN Dehydrogenase/reductase SDR famil...1800.0000002     55.5     26     49GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005777; C:peroxisome; IDA:UniProtKB.
GO:0000253; F:3-keto sterol reductase activity; IDA:UniProtKB.::GO:0018455; F:alcohol dehydrogenase [NAD(P)+ activity; IDA:UniProtKB.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.
GO:0006066; P:alcohol metabolic process; IDA:UniProtKB.::GO:0042180; P:cellular ketone metabolic process; IDA:UniProtKB.::GO:0051262; P:protein tetramerization; IDA:UniProtKB.::GO:0008202; P:steroid metabolic process; IDA:UniProtKB.]
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