Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL113W
Length:
209
Number of sequences:
5887
Description:
YIL113W SDP1 SGDID:S000001375, Chr IX from 150559-151188, Genome Release 64-1-1, Verified ORF, "Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates Slt2p MAP kinase by direct dephosphorylation, diffuse localization under normal conditions shifts to punctate localization after heat shock"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40479    209   SDP1_YEAST Dual-specificity protein phosphata...2098e-154     432     100     100GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:SGD.
GO:0033550; F:MAP kinase tyrosine phosphatase activity; IDA:SGD.::GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IBA:RefGenome.::GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:RefGenome.
2P38590    489   MSG5_YEAST Tyrosine-protein phosphatase MSG5 ...1513e-47     167     52     72GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:SGD.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IMP:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0071511; P:inactivation of MAPK activity involved in conjugation with cellular fusion; IMP:SGD.::GO:0060237; P:regulation of fungal-type cell wall organization; IMP:SGD.::GO:0071701; P:regulation of MAPK export from nucleus; IMP:SGD.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:RefGenome.
3O13453    278   PMP1_SCHPO Tyrosine-protein phosphatase pmp1 ...1955e-33     125     37     58GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; ISS:RefGenome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000165; P:MAPK cascade; NAS:PomBase.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:PomBase.
4P43078    597   PTPX_CANAW Probable tyrosine-protein phosphat...1545e-29     117     43     61
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
5O95147    198   DUS14_HUMAN Dual specificity protein phosphat...870.000000000000001     75.9     40     63
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
6Q17QM8    198   DUS14_BOVIN Dual specificity protein phosphat...870.000000000000001     75.9     40     63
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
7Q9JLY7    198   DUS14_MOUSE Dual specificity protein phosphat...870.000000000000001     75.5     41     64GO:0005737; C:cytoplasm; ISS:MGI.::GO:0005634; C:nucleus; ISS:MGI.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
8O55737    142   123R_IIV6 Putative tyrosine phosphatase 123R ...1300.00000000000001     72     34     53
GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
9Q16690    384   DUS5_HUMAN Dual specificity protein phosphata...1800.0000000000003     70.9     27     46GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0001706; P:endoderm formation; IBA:RefGenome.
10Q63340    280   DUS7_RAT Dual specificity protein phosphatase...770.000000000002     67.4     38     61GO:0005829; C:cytosol; IDA:RGD.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.
11Q6AXW7    204   DUS18_RAT Dual specificity protein phosphatas...760.000000000004     65.5     42     61GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
12Q91Z46    422   DUS7_MOUSE Dual specificity protein phosphata...770.000000000007     67     38     61GO:0005829; C:cytosol; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
13Q16829    419   DUS7_HUMAN Dual specificity protein phosphata...770.000000000007     67     38     61GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
14Q2KJ36    381   DUS6_BOVIN Dual specificity protein phosphata...1100.00000000001     66.6     31     55GO:0005829; C:cytosol; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome.
15Q16828    381   DUS6_HUMAN Dual specificity protein phosphata...1100.00000000001     66.6     31     55GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome.::GO:0051409; P:response to nitrosative stress; IEP:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
16Q9DBB1    381   DUS6_MOUSE Dual specificity protein phosphata...1100.00000000001     66.2     31     55GO:0005829; C:cytosol; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IMP:MGI.
17Q64346    381   DUS6_RAT Dual specificity protein phosphatase...1100.00000000001     66.2     31     55GO:0005829; C:cytosol; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0030154; P:cell differentiation; IEP:RGD.::GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:RGD.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome.::GO:0042493; P:response to drug; IEP:RGD.::GO:0070848; P:response to growth factor stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.
18O54838    384   DUS5_RAT Dual specificity protein phosphatase...1800.00000000001     66.2     26     46GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0001706; P:endoderm formation; IBA:RefGenome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:RGD.
19Q9H596    190   DUS21_HUMAN Dual specificity protein phosphat...900.00000000004     62.8     36     58GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
20Q5R8X2    188   DUS18_PONAB Dual specificity protein phosphat...1270.00000000004     62.4     34     51GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
21Q8NEJ0    188   DUS18_HUMAN Dual specificity protein phosphat...1240.00000000004     62.4     34     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
22Q8VE01    188   DUS18_MOUSE Dual specificity protein phosphat...1230.00000000005     62.4     35     53GO:0031314; C:extrinsic to mitochondrial inner membrane; ISS:MGI.::GO:0031304; C:intrinsic to mitochondrial inner membrane; ISS:MGI.::GO:0005758; C:mitochondrial intermembrane space; ISS:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0006612; P:protein targeting to membrane; ISS:MGI.::GO:0006626; P:protein targeting to mitochondrion; ISS:MGI.::GO:0046677; P:response to antibiotic; ISS:MGI.
23Q0IID7    482   DUS10_BOVIN Dual specificity protein phosphat...620.0000000001     63.5     42     73GO:0005634; C:nucleus; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0043508; P:negative regulation of JUN kinase activity; IBA:RefGenome.
24Q9D9D8    189   DUS21_MOUSE Dual specificity phosphatase 21 O...760.0000000001     61.2     38     61GO:0019898; C:extrinsic to membrane; ISS:MGI.::GO:0005743; C:mitochondrial inner membrane; ISS:MGI.::GO:0005758; C:mitochondrial intermembrane space; ISS:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0006612; P:protein targeting to membrane; ISS:MGI.::GO:0006626; P:protein targeting to mitochondrion; ISS:MGI.
25Q54Y32    856   MPL3_DICDI MAP kinase phosphatase with leucin...630.0000000001     63.9     40     71
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
26Q9ESS0    483   DUS10_MOUSE Dual specificity protein phosphat...620.0000000001     63.5     42     73GO:0005634; C:nucleus; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0046329; P:negative regulation of JNK cascade; IMP:MGI.::GO:0043508; P:negative regulation of JUN kinase activity; IMP:MGI.::GO:0060266; P:negative regulation of respiratory burst involved in inflammatory response; IMP:MGI.::GO:0002819; P:regulation of adaptive immune response; IMP:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.
27Q9Y6W6    482   DUS10_HUMAN Dual specificity protein phosphat...620.0000000001     63.5     42     73GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0043508; P:negative regulation of JUN kinase activity; IBA:RefGenome.
28Q60969    223   STYX_MOUSE Serine/threonine/tyrosine-interact...860.0000000002     61.6     34     51
GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
29Q76I79    1042   SSH1_MOUSE Protein phosphatase Slingshot homo...2030.0000000002     63.5     27     44GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
30Q5BIP9    188   DUS18_BOVIN Dual specificity protein phosphat...760.0000000002     60.8     39     58GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
31Q9M8K7    167   DUS1B_ARATH Dual specificity protein phosphat...890.0000000002     60.5     33     54GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0033549; F:MAP kinase phosphatase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0034599; P:cellular response to oxidative stress; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IC:TAIR.::GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.::GO:0034051; P:negative regulation of plant-type hypersensitive response; IMP:UniProtKB.::GO:0010193; P:response to ozone; IMP:TAIR.
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