rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P40479 | 209 | SDP1_YEAST Dual-specificity protein phosphata... | 209 | 8e-154 | 432 | 100 | 100 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0033550; F:MAP kinase tyrosine phosphatase activity; IDA:SGD.::GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IBA:RefGenome.::GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:RefGenome. | 2 | P38590 | 489 | MSG5_YEAST Tyrosine-protein phosphatase MSG5 ... | 151 | 3e-47 | 167 | 52 | 72 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IMP:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0071511; P:inactivation of MAPK activity involved in conjugation with cellular fusion; IMP:SGD.::GO:0060237; P:regulation of fungal-type cell wall organization; IMP:SGD.::GO:0071701; P:regulation of MAPK export from nucleus; IMP:SGD.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:RefGenome. | 3 | O13453 | 278 | PMP1_SCHPO Tyrosine-protein phosphatase pmp1 ... | 195 | 5e-33 | 125 | 37 | 58 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; ISS:RefGenome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000165; P:MAPK cascade; NAS:PomBase.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:PomBase. | 4 | P43078 | 597 | PTPX_CANAW Probable tyrosine-protein phosphat... | 154 | 5e-29 | 117 | 43 | 61 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 5 | O95147 | 198 | DUS14_HUMAN Dual specificity protein phosphat... | 87 | 0.000000000000001 | 75.9 | 40 | 63 | | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 6 | Q17QM8 | 198 | DUS14_BOVIN Dual specificity protein phosphat... | 87 | 0.000000000000001 | 75.9 | 40 | 63 | | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 7 | Q9JLY7 | 198 | DUS14_MOUSE Dual specificity protein phosphat... | 87 | 0.000000000000001 | 75.5 | 41 | 64 | GO:0005737; C:cytoplasm; ISS:MGI.::GO:0005634; C:nucleus; ISS:MGI. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 8 | O55737 | 142 | 123R_IIV6 Putative tyrosine phosphatase 123R ... | 130 | 0.00000000000001 | 72 | 34 | 53 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 9 | Q16690 | 384 | DUS5_HUMAN Dual specificity protein phosphata... | 180 | 0.0000000000003 | 70.9 | 27 | 46 | GO:0005654; C:nucleoplasm; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc. | | | | | | | | | | GO:0001706; P:endoderm formation; IBA:RefGenome. | 10 | Q63340 | 280 | DUS7_RAT Dual specificity protein phosphatase... | 77 | 0.000000000002 | 67.4 | 38 | 61 | GO:0005829; C:cytosol; IDA:RGD. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD. | | | | | | | | | | | 11 | Q6AXW7 | 204 | DUS18_RAT Dual specificity protein phosphatas... | 76 | 0.000000000004 | 65.5 | 42 | 61 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 12 | Q91Z46 | 422 | DUS7_MOUSE Dual specificity protein phosphata... | 77 | 0.000000000007 | 67 | 38 | 61 | GO:0005829; C:cytosol; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 13 | Q16829 | 419 | DUS7_HUMAN Dual specificity protein phosphata... | 77 | 0.000000000007 | 67 | 38 | 61 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 14 | Q2KJ36 | 381 | DUS6_BOVIN Dual specificity protein phosphata... | 110 | 0.00000000001 | 66.6 | 31 | 55 | GO:0005829; C:cytosol; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome. | 15 | Q16828 | 381 | DUS6_HUMAN Dual specificity protein phosphata... | 110 | 0.00000000001 | 66.6 | 31 | 55 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome.::GO:0051409; P:response to nitrosative stress; IEP:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 16 | Q9DBB1 | 381 | DUS6_MOUSE Dual specificity protein phosphata... | 110 | 0.00000000001 | 66.2 | 31 | 55 | GO:0005829; C:cytosol; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IMP:MGI. | 17 | Q64346 | 381 | DUS6_RAT Dual specificity protein phosphatase... | 110 | 0.00000000001 | 66.2 | 31 | 55 | GO:0005829; C:cytosol; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0030154; P:cell differentiation; IEP:RGD.::GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:RGD.::GO:0043065; P:positive regulation of apoptotic process; IBA:RefGenome.::GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.::GO:0060420; P:regulation of heart growth; IBA:RefGenome.::GO:0042493; P:response to drug; IEP:RGD.::GO:0070848; P:response to growth factor stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD. | 18 | O54838 | 384 | DUS5_RAT Dual specificity protein phosphatase... | 180 | 0.00000000001 | 66.2 | 26 | 46 | GO:0005654; C:nucleoplasm; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0001706; P:endoderm formation; IBA:RefGenome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:RGD. | 19 | Q9H596 | 190 | DUS21_HUMAN Dual specificity protein phosphat... | 90 | 0.00000000004 | 62.8 | 36 | 58 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | | 20 | Q5R8X2 | 188 | DUS18_PONAB Dual specificity protein phosphat... | 127 | 0.00000000004 | 62.4 | 34 | 51 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 21 | Q8NEJ0 | 188 | DUS18_HUMAN Dual specificity protein phosphat... | 124 | 0.00000000004 | 62.4 | 34 | 52 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | | 22 | Q8VE01 | 188 | DUS18_MOUSE Dual specificity protein phosphat... | 123 | 0.00000000005 | 62.4 | 35 | 53 | GO:0031314; C:extrinsic to mitochondrial inner membrane; ISS:MGI.::GO:0031304; C:intrinsic to mitochondrial inner membrane; ISS:MGI.::GO:0005758; C:mitochondrial intermembrane space; ISS:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0006612; P:protein targeting to membrane; ISS:MGI.::GO:0006626; P:protein targeting to mitochondrion; ISS:MGI.::GO:0046677; P:response to antibiotic; ISS:MGI. | 23 | Q0IID7 | 482 | DUS10_BOVIN Dual specificity protein phosphat... | 62 | 0.0000000001 | 63.5 | 42 | 73 | GO:0005634; C:nucleus; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0043508; P:negative regulation of JUN kinase activity; IBA:RefGenome. | 24 | Q9D9D8 | 189 | DUS21_MOUSE Dual specificity phosphatase 21 O... | 76 | 0.0000000001 | 61.2 | 38 | 61 | GO:0019898; C:extrinsic to membrane; ISS:MGI.::GO:0005743; C:mitochondrial inner membrane; ISS:MGI.::GO:0005758; C:mitochondrial intermembrane space; ISS:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0006612; P:protein targeting to membrane; ISS:MGI.::GO:0006626; P:protein targeting to mitochondrion; ISS:MGI. | 25 | Q54Y32 | 856 | MPL3_DICDI MAP kinase phosphatase with leucin... | 63 | 0.0000000001 | 63.9 | 40 | 71 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 26 | Q9ESS0 | 483 | DUS10_MOUSE Dual specificity protein phosphat... | 62 | 0.0000000001 | 63.5 | 42 | 73 | GO:0005634; C:nucleus; IBA:RefGenome. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046329; P:negative regulation of JNK cascade; IMP:MGI.::GO:0043508; P:negative regulation of JUN kinase activity; IMP:MGI.::GO:0060266; P:negative regulation of respiratory burst involved in inflammatory response; IMP:MGI.::GO:0002819; P:regulation of adaptive immune response; IMP:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI. | 27 | Q9Y6W6 | 482 | DUS10_HUMAN Dual specificity protein phosphat... | 62 | 0.0000000001 | 63.5 | 42 | 73 | GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0043508; P:negative regulation of JUN kinase activity; IBA:RefGenome. | 28 | Q60969 | 223 | STYX_MOUSE Serine/threonine/tyrosine-interact... | 86 | 0.0000000002 | 61.6 | 34 | 51 | | | | | | | | | | | GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 29 | Q76I79 | 1042 | SSH1_MOUSE Protein phosphatase Slingshot homo... | 203 | 0.0000000002 | 63.5 | 27 | 44 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome. | 30 | Q5BIP9 | 188 | DUS18_BOVIN Dual specificity protein phosphat... | 76 | 0.0000000002 | 60.8 | 39 | 58 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 31 | Q9M8K7 | 167 | DUS1B_ARATH Dual specificity protein phosphat... | 89 | 0.0000000002 | 60.5 | 33 | 54 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0033549; F:MAP kinase phosphatase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0034599; P:cellular response to oxidative stress; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IC:TAIR.::GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.::GO:0034051; P:negative regulation of plant-type hypersensitive response; IMP:UniProtKB.::GO:0010193; P:response to ozone; IMP:TAIR. |