Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL113W
Length:
209
Number of sequences:
5887
Description:
YIL113W SDP1 SGDID:S000001375, Chr IX from 150559-151188, Genome Release 64-1-1, Verified ORF, "Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates Slt2p MAP kinase by direct dephosphorylation, diffuse localization under normal conditions shifts to punctate localization after heat shock"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q6GQJ8    209   DUS22_XENLA Dual specificity protein phosphat...670.00001     48.1     33     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
92P0C591    219   DUPD1_BOVIN Dual specificity phosphatase DUPD...950.00001     48.1     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
93Q9EMX1    165   PTPH_AMEPV Putative tyrosine-protein phosphat...940.00001     47     31     55
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
94Q8WTR2    217   DUS19_HUMAN Dual specificity protein phosphat...730.00001     47.8     29     51GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0008579; F:JUN kinase phosphatase activity; IBA:RefGenome.::GO:0005078; F:MAP-kinase scaffold activity; ISS:BHF-UCL.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; ISS:BHF-UCL.::GO:0030295; F:protein kinase activator activity; ISS:BHF-UCL.::GO:0004860; F:protein kinase inhibitor activity; ISS:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007254; P:JNK cascade; IBA:RefGenome.::GO:0046329; P:negative regulation of JNK cascade; ISS:BHF-UCL.::GO:0043508; P:negative regulation of JUN kinase activity; ISS:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; ISS:BHF-UCL.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:BHF-UCL.
95Q5XHB2    209   DUS22_XENTR Dual specificity protein phosphat...670.00002     47.4     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome.
96Q8R4V2    235   DUS15_MOUSE Dual specificity protein phosphat...770.00004     46.6     32     49
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
97Q02256    364   PVH1_YEAST Tyrosine-protein phosphatase YVH1 ...600.00004     47     37     57GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:SGD.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0030476; P:ascospore wall assembly; IMP:SGD.::GO:0019933; P:cAMP-mediated signaling; IMP:SGD.::GO:0007126; P:meiosis; IMP:SGD.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0000027; P:ribosomal large subunit assembly; IMP:SGD.
98Q8K4T5    220   DUS19_MOUSE Dual specificity protein phosphat...910.00005     46.2     27     46
GO:0005078; F:MAP-kinase scaffold activity; IDA:BHF-UCL.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:BHF-UCL.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:BHF-UCL.::GO:0030295; F:protein kinase activator activity; IDA:BHF-UCL.::GO:0004860; F:protein kinase inhibitor activity; IDA:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0046329; P:negative regulation of JNK cascade; IDA:BHF-UCL.::GO:0043508; P:negative regulation of JUN kinase activity; IDA:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:BHF-UCL.
99Q9H1R2    295   DUS15_HUMAN Dual specificity protein phosphat...740.00005     46.6     32     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
100Q8TE77    659   SSH3_HUMAN Protein phosphatase Slingshot homo...1140.00007     46.6     28     50GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
101P0C5A0    206   DUPD1_GASAC Dual specificity phosphatase DUPD...750.00008     45.4     35     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
102P0C595    215   DUPD1_RAT Dual specificity phosphatase DUPD1 ...950.00009     45.4     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
103P38148    807   PPS1_YEAST Dual specificity protein phosphata...580.00009     46.2     36     60GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005634; C:nucleus; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IBA:RefGenome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:RefGenome.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IGI:SGD.
104Q5VZP5    1158   DUS27_HUMAN Inactive dual specificity phospha...600.0001     46.2     40     65
GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
105Q9UII6    198   DUS13_HUMAN Dual specificity protein phosphat...810.0001     45.1     31     57
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0007126; P:meiosis; TAS:ProtInc.::GO:0007283; P:spermatogenesis; TAS:ProtInc.
106Q8BK84    215   DUPD1_MOUSE Dual specificity phosphatase DUPD...1000.0001     45.1     36     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
107Q5XIS1    652   SSH3_RAT Protein phosphatase Slingshot homolo...1140.0001     45.8     26     50GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
108Q5RD73    185   DUS3_PONAB Dual specificity protein phosphata...650.0001     44.7     32     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
109P51452    185   DUS3_HUMAN Dual specificity protein phosphata...650.0001     44.7     32     58GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0033549; F:MAP kinase phosphatase activity; IMP:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.::GO:0050868; P:negative regulation of T cell activation; IDA:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
110Q5UR74    212   PTPH_MIMIV Putative tyrosine-protein phosphat...670.0001     45.1     31     51
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
111Q9JIM4    339   DUS12_RAT Dual specificity protein phosphatas...890.0002     45.1     26     53GO:0005737; C:cytoplasm; IDA:RGD.
GO:0019900; F:kinase binding; IPI:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0033133; P:positive regulation of glucokinase activity; IDA:RGD.
112Q55E39    212   DUSP1_DICDI Probable dual specificity protein...690.0002     44.7     33     54
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
113Q68J44    220   DUPD1_HUMAN Dual specificity phosphatase DUPD...990.0002     44.3     33     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
114P0C5A2    211   DUPD1_CALMI Dual specificity phosphatase DUPD...790.0004     43.5     33     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
115Q148W8    1138   DUS27_MOUSE Inactive dual specificity phospha...590.0005     43.9     36     64
GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
116P0C5A1    203   DUPD1_ORYLA Dual specificity phosphatase DUPD...1750.0005     43.1     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
117P0C594    220   DUPD1_PANTR Dual specificity phosphatase DUPD...760.0005     43.1     36     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
118Q9D7X3    185   DUS3_MOUSE Dual specificity protein phosphata...650.0008     42.4     32     57GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0033549; F:MAP kinase phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:MGI.
GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0050868; P:negative regulation of T cell activation; IBA:RefGenome.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IBA:RefGenome.::GO:0045931; P:positive regulation of mitotic cell cycle; IBA:RefGenome.
119Q29RA3    189   DUPD1_DANRE Dual specificity phosphatase DUPD...610.0008     42.4     39     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
120Q75QN6    929   PHS1_ARATH Dual specificity protein phosphata...1300.0008     43.5     26     45GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043622; P:cortical microtubule organization; IMP:TAIR.::GO:0010468; P:regulation of gene expression; IMP:TAIR.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.
121Q1LWL2    208   DS22A_DANRE Dual specificity protein phosphat...680.001     42.4     28     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome.
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