Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL112W
Length:
1083
Number of sequences:
5887
Description:
YIL112W HOS4 SGDID:S000001374, Chr IX from 151595-154846, Genome Release 64-1-1, Verified ORF, "Subunit of the Set3 complex, which is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40480    1083   HOS4_YEAST Protein HOS4 OS=Saccharomyces cere...10830     2217     100     100GO:0034967; C:Set3 complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0016575; P:histone deacetylation; IDA:SGD.::GO:0045835; P:negative regulation of meiosis; IPI:SGD.
2Q8IWZ3    2542   ANKH1_HUMAN Ankyrin repeat and KH domain-cont...2174.9     35     25     41GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
3Q9ULJ7    1429   ANR50_HUMAN Ankyrin repeat domain-containing ...1480.0007     47.8     30     43
4Q5F478    990   ANR44_CHICK Serine/threonine-protein phosphat...1470.99     37.4     24     41
5Q9ULH0    1771   KDIS_HUMAN Kinase D-interacting substrate of ...951.1     37.4     33     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.
6Q8N8A2    993   ANR44_HUMAN Serine/threonine-protein phosphat...1000.54     38.1     32     51
GO:0005515; F:protein binding; IPI:IntAct.
7Q01484    3957   ANK2_HUMAN Ankyrin-2 OS=Homo sapiens (Human)....1250.000006     54.7     33     47GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007165; P:signal transduction; IEA:InterPro.
8Q9EQG6    1762   KDIS_RAT Kinase D-interacting substrate of 22...2950.000001     56.6     23     40GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0019901; F:protein kinase binding; IDA:RGD.::GO:0019887; F:protein kinase regulator activity; IDA:RGD.
9B2RXR6    993   ANR44_MOUSE Serine/threonine-protein phosphat...1070.53     38.1     32     50
10Q502K3    1071   ANR52_DANRE Serine/threonine-protein phosphat...2164.3     35     25     40
11Q8N7Z5    1873   ANR31_HUMAN Ankyrin repeat domain-containing ...1131.1     37     29     43
12Q12955    4377   ANK3_HUMAN Ankyrin-3 OS=Homo sapiens (Human)....1070.0004     48.5     31     46GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045184; P:establishment of protein localization; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
13Q8C8R3    3898   ANK2_MOUSE Ankyrin-2 OS=Mus musculus (Mouse)....1250.00002     53.1     32     47GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0060048; P:cardiac muscle contraction; IMP:MGI.::GO:0034394; P:protein localization at cell surface; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
14O75179    2603   ANR17_HUMAN Ankyrin repeat domain-containing ...2598     34.3     21     36GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
15Q9VCA8    4001   ANKHM_DROME Ankyrin repeat and KH domain-cont...526.8     34.7     37     54GO:0005811; C:lipid particle; IDA:FlyBase.
GO:0019887; F:protein kinase regulator activity; IGI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0019730; P:antimicrobial humoral response; IMP:FlyBase.::GO:0051298; P:centrosome duplication; IMP:FlyBase.::GO:0001751; P:compound eye photoreceptor cell differentiation; IMP:FlyBase.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IGI:FlyBase.
16Q9H2K2    1166   TNKS2_HUMAN Tankyrase-2 OS=Homo sapiens (Huma...909.7     33.9     32     46GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0000784; C:nuclear chromosome, telomeric region; IC:BHF-UCL.::GO:0005635; C:nuclear envelope; IDA:BHF-UCL.::GO:0000242; C:pericentriolar material; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0032212; P:positive regulation of telomere maintenance via telomerase; IC:BHF-UCL.::GO:0070213; P:protein auto-ADP-ribosylation; IDA:UniProtKB.::GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
17Q3UES3    1166   TNKS2_MOUSE Tankyrase-2 OS=Mus musculus (Mous...670.002     45.8     36     57GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.
GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
18Q6PFX9    1320   TNKS1_MOUSE Tankyrase-1 OS=Mus musculus (Mous...680.0009     47.4     40     62GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
19O95271    1327   TNKS1_HUMAN Tankyrase-1 OS=Homo sapiens (Huma...680.0008     47.4     40     62GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0000784; C:nuclear chromosome, telomeric region; IDA:BHF-UCL.::GO:0031965; C:nuclear membrane; TAS:BHF-UCL.::GO:0005643; C:nuclear pore; TAS:BHF-UCL.::GO:0000242; C:pericentriolar material; TAS:BHF-UCL.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:BHF-UCL.
GO:0007052; P:mitotic spindle organization; TAS:BHF-UCL.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0043392; P:negative regulation of DNA binding; IDA:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0032212; P:positive regulation of telomere maintenance via telomerase; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; IDA:UniProtKB.::GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.::GO:0070212; P:protein poly-ADP-ribosylation; IDA:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; TAS:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
20Q7T163    1672   KDIS_DANRE Kinase D-interacting substrate of ...3130.000000000003     75.1     25     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
21Q8CGN4    1759   BCOR_MOUSE BCL-6 corepressor OS=Mus musculus ...1150.001     46.6     35     47
GO:0005515; F:protein binding; IPI:MGI.::GO:0003714; F:transcription corepressor activity; IPI:MGI.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22Q71S21    1002   INVSB_XENLA Inversin-B OS=Xenopus laevis (Afr...980.00009     50.4     36     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
23Q6W2J9    1755   BCOR_HUMAN BCL-6 corepressor OS=Homo sapiens ...1150.0002     49.3     36     48GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0031072; F:heat shock protein binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IMP:UniProtKB.
GO:0007507; P:heart development; IMP:UniProtKB.::GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.::GO:0030502; P:negative regulation of bone mineralization; IMP:UniProtKB.::GO:0000415; P:negative regulation of histone H3-K36 methylation; IMP:UniProtKB.::GO:0051572; P:negative regulation of histone H3-K4 methylation; IMP:UniProtKB.::GO:0070171; P:negative regulation of tooth mineralization; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0042476; P:odontogenesis; IMP:UniProtKB.::GO:0060021; P:palate development; IMP:UniProtKB.::GO:0065001; P:specification of axis polarity; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24Q99728    777   BARD1_HUMAN BRCA1-associated RING domain prot...921.1     37     32     45GO:0070531; C:BRCA1-A complex; IDA:UniProtKB.::GO:0031436; C:BRCA1-BARD1 complex; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; NAS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0031441; P:negative regulation of mRNA 3'-end processing; NAS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; NAS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0042325; P:regulation of phosphorylation; IMP:UniProtKB.::GO:0001894; P:tissue homeostasis; TAS:UniProtKB.
25Q6UB99    2663   ANR11_HUMAN Ankyrin repeat domain-containing ...1130.00005     51.6     29     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
26Q99NH0    2603   ANR17_MOUSE Ankyrin repeat domain-containing ...525.4     35     38     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0007492; P:endoderm development; TAS:MGI.
27A9JR78    1427   TONSL_DANRE Tonsoku-like protein OS=Danio rer...1070.0009     47.4     30     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043596; C:nuclear replication fork; ISS:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.
GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0031297; P:replication fork processing; ISS:UniProtKB.
28Q9VSA4    1405   TONSL_DROME Tonsoku-like protein OS=Drosophil...1629e-16     86.7     35     55
GO:0005488; F:binding; IEA:InterPro.
29Q4UMH6    1179   Y381_RICFE Putative ankyrin repeat protein RF...700.77     37.7     30     54
GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
30Q9QZH2    768   BARD1_RAT BRCA1-associated RING domain protei...1400.000000000000003     84.3     41     56GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0042325; P:regulation of phosphorylation; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEP:RGD.
31A2AQH4    1781   BCORL_MOUSE BCL-6 corepressor-like protein 1 ...740.14     40     38     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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