Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL112W
Length:
1083
Number of sequences:
5887
Description:
YIL112W HOS4 SGDID:S000001374, Chr IX from 151595-154846, Genome Release 64-1-1, Verified ORF, "Subunit of the Set3 complex, which is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
931Q09YK6    477   ASZ1_ATEGE Ankyrin repeat, SAM and basic leuc...586.4     34.3     40     52GO:0071546; C:pi-body; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.::GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0007140; P:male meiosis; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
932Q9R172    2319   NOTC3_RAT Neurogenic locus notch homolog prot...1065.3     35     32     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007219; P:Notch signaling pathway; IDA:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IDA:RGD.::GO:0042246; P:tissue regeneration; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
933Q0VC93    158   ANR37_BOVIN Ankyrin repeat domain-containing ...1282.8     34.3     27     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
934P46531    2555   NOTC1_HUMAN Neurogenic locus notch homolog pr...1377.9     34.3     29     41GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; NAS:UniProtKB.::GO:0002193; C:MAML1-RBP-Jkappa- ICN1 complex; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001047; F:core promoter binding; ISS:UniProtKB.::GO:0019899; F:enzyme binding; ISS:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; ISS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0003180; P:aortic valve morphogenesis; IMP:BHF-UCL.::GO:2000811; P:negative regulation of anoikis; IMP:BHF-UCL.::GO:0030514; P:negative regulation of BMP signaling pathway; ISS:BHF-UCL.::GO:0010812; P:negative regulation of cell-substrate adhesion; IDA:BHF-UCL.::GO:0060253; P:negative regulation of glial cell proliferation; ISS:UniProtKB.::GO:0045662; P:negative regulation of myoblast differentiation; IMP:UniProtKB.::GO:0010832; P:negative regulation of myotube differentiation; ISS:UniProtKB.::GO:0048715; P:negative regulation of oligodendrocyte differentiation; ISS:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:BHF-UCL.::GO:2000974; P:negative regulation of pro-B cell differentiation; ISS:UniProtKB.::GO:2000737; P:negative regulation of stem cell differentiation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0097150; P:neuronal stem cell maintenance; IEP:UniProtKB.::GO:0007220; P:Notch receptor processing; TAS:Reactome.::GO:0048711; P:positive regulation of astrocyte differentiation; ISS:UniProtKB.::GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.::GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.::GO:0046427; P:positive regulation of JAK-STAT cascade; ISS:UniProtKB.::GO:0061419; P:positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; ISS:UniProtKB.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
935Q3J9B6    845   IF2_NITOC Translation initiation factor IF-2 ...652.9     35.8     40     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
936P17558    318   RTPT_YEAST 37S ribosomal protein PET123, mito...713     35     41     58GO:0005763; C:mitochondrial small ribosomal subunit; IPI:SGD.
GO:0003735; F:structural constituent of ribosome; IPI:SGD.
GO:0032543; P:mitochondrial translation; IC:SGD.
937Q63369    522   NFKB1_RAT Nuclear factor NF-kappa-B p105 subu...1199.1     33.9     26     50GO:0005829; C:cytosol; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0031072; F:heat shock protein binding; IPI:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:RGD.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:RGD.
GO:0006916; P:anti-apoptosis; IMP:RGD.::GO:0009617; P:response to bacterium; IEP:RGD.::GO:0046688; P:response to copper ion; IEP:RGD.::GO:0006979; P:response to oxidative stress; IDA:RGD.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
938Q9NWX5    421   ASB6_HUMAN Ankyrin repeat and SOCS box protei...805.3     34.7     35     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
939Q5UNX2    275   YL715_MIMIV Putative ankyrin repeat protein L...563.3     35     38     61
940Q9J512    141   V223_FOWPN Putative ankyrin repeat protein FP...759.6     32.3     36     49
941Q93650    583   GLS2_CAEEL Putative glutaminase F30F8.2 OS=Ca...1063.6     35.4     29     46
GO:0004359; F:glutaminase activity; IEA:EC.
GO:0006541; P:glutamine metabolic process; IEA:InterPro.
942Q1RJM6    97   Y357_RICBR Putative ankyrin repeat protein RB...583.7     32.7     31     62
943Q5UPK1    339   YL120_MIMIV Putative ankyrin repeat protein L...893.8     35     30     52
944Q54HT1    1336   TIRA_DICDI Protein tirA OS=Dictyostelium disc...804     35.4     33     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0008283; P:cell proliferation; IMP:dictyBase.::GO:0006952; P:defense response; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro.
945Q8IZ07    590   AN13A_HUMAN Ankyrin repeat domain-containing ...954     35     28     52
946Q91ZU1    418   ASB6_MOUSE Ankyrin repeat and SOCS box protei...1134.2     35     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
947P35845    1188   OSH1_YEAST Oxysterol-binding protein homolog ...2484.4     35     24     35GO:0005769; C:early endosome; IDA:SGD.::GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0000138; C:Golgi trans cisterna; IDA:SGD.::GO:0005640; C:nuclear outer membrane; IEA:UniProtKB-SubCell.
GO:0005545; F:1-phosphatidylinositol binding; ISS:SGD.::GO:0008142; F:oxysterol binding; ISS:SGD.::GO:0015248; F:sterol transporter activity; IDA:SGD.
948Q5R4M7    421   ASB6_PONAB Ankyrin repeat and SOCS box protei...807.9     33.9     34     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
949P19838    968   NFKB1_HUMAN Nuclear factor NF-kappa-B p105 su...564.9     35     32     63GO:0005829; C:cytosol; TAS:Reactome.::GO:0033256; C:I-kappaB/NF-kappaB complex; TAS:BHF-UCL.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB.
GO:0006916; P:anti-apoptosis; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071347; P:cellular response to interleukin-1; IEP:BHF-UCL.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0010956; P:negative regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0032269; P:negative regulation of cellular protein metabolic process; IC:BHF-UCL.::GO:0032375; P:negative regulation of cholesterol transport; IC:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0010957; P:negative regulation of vitamin D biosynthetic process; IC:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:1900127; P:positive regulation of hyaluronan biosynthetic process; IDA:UniProtKB.::GO:0010884; P:positive regulation of lipid storage; IC:BHF-UCL.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IC:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:UniProtKB.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
950Q8IDX6    3130   RBP2A_PLAF7 Reticulocyte-binding protein 2 ho...1225.2     35     30     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.
951Q9J503    482   V232_FOWPN Putative ankyrin repeat protein FP...725.3     34.7     33     58
952A2ARZ3    6995   FSIP2_MOUSE Fibrous sheath-interacting protei...1217.4     34.7     30     50GO:0009434; C:microtubule-based flagellum; IC:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.
953Q6F3J0    972   NFKB1_CANFA Nuclear factor NF-kappa-B p105 su...1067.5     34.3     31     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000975; F:regulatory region DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
954Q5F4B2    586   SWP70_CHICK Switch-associated protein 70 OS=G...797.9     34.3     35     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
955Q5UP66    274   YR597_MIMIV Putative ankyrin repeat protein R...708.7     33.5     31     54
956P25799    971   NFKB1_MOUSE Nuclear factor NF-kappa-B p105 su...569     33.9     34     61GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0000975; F:regulatory region DNA binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048535; P:lymph node development; TAS:MGI.::GO:0001818; P:negative regulation of cytokine production; IMP:BHF-UCL.::GO:0045083; P:negative regulation of interleukin-12 biosynthetic process; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
957O14964    777   HGS_HUMAN Hepatocyte growth factor-regulated ...959.4     33.9     26     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0046426; P:negative regulation of JAK-STAT cascade; IDA:HGNC.::GO:0042176; P:regulation of protein catabolic process; TAS:HGNC.
958Q9JJ50    776   HGS_RAT Hepatocyte growth factor-regulated ty...959.6     33.9     26     56GO:0005829; C:cytosol; IDA:RGD.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.::GO:0030141; C:secretory granule; IDA:RGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; NAS:RGD.
GO:0008333; P:endosome to lysosome transport; IMP:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.
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