Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL095W
Length:
810
Number of sequences:
5887
Description:
YIL095W PRK1 SGDID:S000001357, Chr IX from 183937-186369, Genome Release 64-1-1, Verified ORF, "Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40494    810   PRK1_YEAST Actin-regulating kinase PRK1 OS=Sa...8100     1669     100     100GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0000147; P:actin cortical patch assembly; TAS:SGD.::GO:0007015; P:actin filament organization; IMP:SGD.::GO:0000910; P:cytokinesis; TAS:SGD.::GO:0030100; P:regulation of endocytosis; IMP:SGD.
2P53974    638   ARK1_YEAST Actin-regulating kinase 1 OS=Sacch...3792e-164     498     63     78GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0000147; P:actin cortical patch assembly; TAS:SGD.::GO:0007015; P:actin filament organization; IMP:SGD.::GO:0000910; P:cytokinesis; TAS:SGD.::GO:0030100; P:regulation of endocytosis; IMP:SGD.
3O43066    953   PPK30_SCHPO Serine/threonine-protein kinase p...2982e-92     317     49     65GO:0030479; C:actin cortical patch; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:PomBase.
GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.
4Q9USS2    872   PPK29_SCHPO Serine/threonine-protein kinase p...3013e-87     301     48     65GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:PomBase.
GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0065007; P:biological regulation; NAS:PomBase.
5P38080    1108   AKL1_YEAST Serine/threonine-protein kinase AK...3322e-86     302     45     62GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; IMP:SGD.::GO:0030100; P:regulation of endocytosis; IMP:SGD.
6Q9UU85    650   PPK38_SCHPO Protein kinase domain-containing ...3006e-84     287     47     61GO:0030479; C:actin cortical patch; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:PomBase.
GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.
7F1MH24    957   AAK1_BOVIN AP2-associated protein kinase 1 OS...2963e-60     224     38     56GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; ISS:UniProtKB.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; IDA:UniProtKB.::GO:0043195; C:terminal button; ISS:UniProtKB.
GO:0035612; F:AP-2 adaptor complex binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005112; F:Notch binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045747; P:positive regulation of Notch signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
8Q2M2I8    961   AAK1_HUMAN AP2-associated protein kinase 1 OS...2964e-60     223     38     56GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; ISS:UniProtKB.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0043195; C:terminal button; ISS:UniProtKB.
GO:0035612; F:AP-2 adaptor complex binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005112; F:Notch binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045747; P:positive regulation of Notch signaling pathway; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050821; P:protein stabilization; IDA:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; IDA:UniProtKB.::GO:0032880; P:regulation of protein localization; IDA:UniProtKB.
9F1SPM8    968   AAK1_PIG AP2-associated protein kinase 1 OS=S...2965e-60     223     38     56GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; IDA:UniProtKB.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0043195; C:terminal button; ISS:UniProtKB.
GO:0035612; F:AP-2 adaptor complex binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005112; F:Notch binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045747; P:positive regulation of Notch signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; IDA:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
10Q54VV7    1126   Y0111_DICDI Probable serine/threonine-protein...2932e-59     223     38     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
11Q3UHJ0    959   AAK1_MOUSE AP2-associated protein kinase 1 OS...2962e-59     221     37     56GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; ISS:UniProtKB.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0043195; C:terminal button; ISS:UniProtKB.
GO:0035612; F:AP-2 adaptor complex binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005112; F:Notch binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045747; P:positive regulation of Notch signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
12Q9NSY1    1161   BMP2K_HUMAN BMP-2-inducible protein kinase OS...2952e-58     220     37     56GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
13Q91Z96    1138   BMP2K_MOUSE BMP-2-inducible protein kinase OS...2951e-57     218     37     57GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019208; F:phosphatase regulator activity; IDA:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0030500; P:regulation of bone mineralization; IDA:MGI.
14P0C1X8    962   AAK1_RAT AP2-associated protein kinase 1 OS=R...2963e-57     215     37     55GO:0031252; C:cell leading edge; IDA:UniProtKB.::GO:0071439; C:clathrin complex; IDA:UniProtKB.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0043195; C:terminal button; IDA:UniProtKB.
GO:0035612; F:AP-2 adaptor complex binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005112; F:Notch binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045747; P:positive regulation of Notch signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; IDA:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
15Q86HW6    798   Y6461_DICDI Probable serine/threonine-protein...2909e-57     212     38     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
16O14976    1311   GAK_HUMAN Cyclin-G-associated kinase OS=Homo ...3009e-42     169     35     54GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
17P97874    1305   GAK_RAT Cyclin-G-associated kinase OS=Rattus ...2995e-41     166     34     54GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IDA:RGD.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
18Q99KY4    1305   GAK_MOUSE Cyclin-G-associated kinase OS=Mus m...2997e-41     166     34     54GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
19O75716    305   STK16_HUMAN Serine/threonine-protein kinase 1...2844e-21     99     27     50GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
20Q54QQ1    1387   PHG2_DICDI Serine/threonine-protein kinase ph...2983e-20     100     28     47GO:0030666; C:endocytic vesicle membrane; IDA:dictyBase.::GO:0005886; C:plasma membrane; IDA:dictyBase.
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.::GO:0017016; F:Ras GTPase binding; IPI:dictyBase.
GO:0007015; P:actin filament organization; IMP:dictyBase.::GO:0000902; P:cell morphogenesis; IMP:dictyBase.::GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006928; P:cellular component movement; IMP:dictyBase.::GO:0031670; P:cellular response to nutrient; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0006909; P:phagocytosis; IMP:dictyBase.::GO:0051489; P:regulation of filopodium assembly; IMP:dictyBase.::GO:0031156; P:regulation of sorocarp development; IMP:dictyBase.
21Q9R0A5    511   NEK3_MOUSE Serine/threonine-protein kinase Ne...2204e-20     98.6     30     49GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
22P57760    305   STK16_RAT Serine/threonine-protein kinase 16 ...2865e-20     95.9     26     49GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:RGD.
GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.
23O88697    305   STK16_MOUSE Serine/threonine-protein kinase 1...2868e-19     92     25     48GO:0005798; C:Golgi-associated vesicle; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
24Q54RJ4    979   IKSA_DICDI Probable serine/threonine-protein ...3098e-19     95.5     27     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
25P51954    1203   NEK1_MOUSE Serine/threonine-protein kinase Ne...2761e-18     95.1     29     48GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IMP:MGI.::GO:0010212; P:response to ionizing radiation; IMP:MGI.
26B4KYX8    778   PLK4_DROMO Serine/threonine-protein kinase PL...2701e-18     94.4     28     47GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
27P51956    506   NEK3_HUMAN Serine/threonine-protein kinase Ne...2902e-18     93.2     27     46GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; NAS:UniProtKB.
28Q0IHQ8    951   STK10_XENTR Serine/threonine-protein kinase 1...2782e-18     94     26     48GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB.
29Q54RR9    1761   Y9844_DICDI Probable serine/threonine-protein...2936e-18     93.2     26     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
30Q6P3R8    708   NEK5_HUMAN Serine/threonine-protein kinase Ne...2779e-18     91.7     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
31Q96PY6    1258   NEK1_HUMAN Serine/threonine-protein kinase Ne...2221e-17     92     31     48GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0000242; C:pericentriolar material; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
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