Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL095W
Length:
810
Number of sequences:
5887
Description:
YIL095W PRK1 SGDID:S000001357, Chr IX from 183937-186369, Genome Release 64-1-1, Verified ORF, "Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
871Q68Y49    508   CIPKJ_ORYSJ CBL-interacting protein kinase 19...3110.00000001     62     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
872Q91009    778   NTRK1_CHICK High affinity nerve growth factor...2430.00000001     62.4     24     44GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048406; F:nerve growth factor binding; ISS:UniProtKB.::GO:0010465; F:nerve growth factor receptor activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; ISS:UniProtKB.
GO:0060385; P:axonogenesis involved in innervation; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0032320; P:positive regulation of Ras GTPase activity; ISS:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.
873P34314    965   TLK1_CAEEL Serine/threonine-protein kinase to...2960.00000001     62.4     26     42GO:0000790; C:nuclear chromatin; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IMP:UniProtKB.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0045860; P:positive regulation of protein kinase activity; IDA:WormBase.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006479; P:protein methylation; IMP:WormBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
874Q9QZS5    367   SGK2_MOUSE Serine/threonine-protein kinase Sg...1640.00000001     61.2     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015459; F:potassium channel regulator activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
875P29597    1187   TYK2_HUMAN Non-receptor tyrosine-protein kina...2240.00000001     62.4     25     46GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005131; F:growth hormone receptor binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.
GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
876Q20845    615   PLK3_CAEEL Serine/threonine-protein kinase pl...2710.00000001     62     24     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
877Q00372    612   SNF1_CANGA Carbon catabolite-derepressing pro...2860.00000001     62     25     45GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
878P53739    893   FPK1_YEAST Flippase kinase 1 OS=Saccharomyces...1980.00000001     62.4     24     43GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IMP:SGD.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:SGD.::GO:0019236; P:response to pheromone; IMP:SGD.
879Q8VCR8    613   MYLK2_MOUSE Myosin light chain kinase 2, skel...2000.00000001     62     25     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0055007; P:cardiac muscle cell differentiation; IEP:UniProtKB.::GO:0007274; P:neuromuscular synaptic transmission; IMP:MGI.::GO:0014816; P:satellite cell differentiation; IMP:UniProtKB.::GO:0035914; P:skeletal muscle cell differentiation; IEP:UniProtKB.
880Q0CL79    1342   SEPH_ASPTN Cytokinesis protein sepH OS=Asperg...2190.00000001     62.4     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
881O94168    619   SNF1_CANTR Carbon catabolite-derepressing pro...2860.00000001     62     24     45GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
882Q28948    552   AAPK2_PIG 5'-AMP-activated protein kinase cat...2480.00000001     61.6     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
883Q6H9I1    952   ATG1_BOTFU Serine/threonine-protein kinase AT...3110.00000001     62.4     24     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
884A6RYB8    952   ATG1_BOTFB Serine/threonine-protein kinase at...3110.00000001     62.4     24     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
885O64556    877   Y2923_ARATH Putative leucine-rich repeat rece...2170.00000001     62     26     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
886Q7X996    443   CIPK2_ORYSJ CBL-interacting protein kinase 2 ...2750.00000001     61.6     25     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
887Q6PAD2    944   PLK4_XENLA Serine/threonine-protein kinase PL...2000.00000001     62     30     47GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.
888Q550L8    1358   IFKB_DICDI Probable serine/threonine-protein ...2250.00000001     62.4     24     45GO:0005622; C:intracellular; IC:dictyBase.
GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; ISS:dictyBase.::GO:0000049; F:tRNA binding; IEA:InterPro.
GO:0016337; P:cell-cell adhesion; IGI:dictyBase.::GO:0031589; P:cell-substrate adhesion; IGI:dictyBase.
889Q9C562    479   CIPKA_ARATH CBL-interacting serine/threonine-...2780.00000002     61.6     25     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
890P62343    524   CDPK1_PLAFK Calcium-dependent protein kinase ...1900.00000002     61.6     27     45GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
891P62344    524   CDPK1_PLAF7 Calcium-dependent protein kinase ...1900.00000002     61.6     27     45GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
892C0LGV0    895   Y5487_ARATH Probable LRR receptor-like serine...2430.00000002     62     28     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
893Q99KH8    431   STK24_MOUSE Serine/threonine-protein kinase 2...1940.00000002     61.2     27     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008631; P:induction of apoptosis by oxidative stress; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
894P42686    505   SRK1_SPOLA Tyrosine-protein kinase isoform SR...2190.00000002     61.6     24     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
895B0LT89    431   STK24_RAT Serine/threonine-protein kinase 24 ...1940.00000002     61.2     27     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008631; P:induction of apoptosis by oxidative stress; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0048680; P:positive regulation of axon regeneration; IMP:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
896Q9P1W9    311   PIM2_HUMAN Serine/threonine-protein kinase pi...1800.00000002     60.5     32     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0007140; P:male meiosis; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0050821; P:protein stabilization; IMP:UniProtKB.::GO:0009615; P:response to virus; IEP:UniProtKB.
897Q5B4Z3    1346   SEPH_EMENI Cytokinesis protein sepH OS=194 / ...2210.00000002     62.4     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
898P87253    1142   KPC1_NEUCR Protein kinase C-like OS=1257 / FG...2850.00000002     62     22     42GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
899Q13976    671   KGP1_HUMAN cGMP-dependent protein kinase 1 OS...2680.00000002     62     26     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; IDA:UniProtKB.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0090331; P:negative regulation of platelet aggregation; IMP:UniProtKB.::GO:0043087; P:regulation of GTPase activity; IMP:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
900P00516    671   KGP1_BOVIN cGMP-dependent protein kinase 1 OS...2680.00000002     61.6     26     45GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; ISS:UniProtKB.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; ISS:UniProtKB.
GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0043087; P:regulation of GTPase activity; ISS:UniProtKB.
901Q9ZQR3    868   Y2451_ARATH Leucine-rich repeat receptor-like...3340.00000002     62     26     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
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