Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL095W
Length:
810
Number of sequences:
5887
Description:
YIL095W PRK1 SGDID:S000001357, Chr IX from 183937-186369, Genome Release 64-1-1, Verified ORF, "Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
571Q03147    346   CDK7_MOUSE Cyclin-dependent kinase 7 OS=Mus m...2270.0000000004     65.9     26     45GO:0005675; C:holo TFIIH complex; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008094; F:DNA-dependent ATPase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
572Q9Y2K2    1263   SIK3_HUMAN Serine/threonine-protein kinase SI...2360.0000000004     67.4     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
573Q8R9T6    625   PKN1_THETN Probable serine/threonine-protein ...2810.0000000004     67     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
574Q8XJL8    685   PKN2_CLOPE Probable serine/threonine-protein ...2660.0000000004     67     21     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
575Q55DD4    1678   PAKD_DICDI Serine/threonine-protein kinase pa...2550.0000000004     67.4     25     42GO:0016592; C:mediator complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
576Q922K9    512   FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus ...2700.0000000004     66.6     23     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
577P15056    766   BRAF_HUMAN Serine/threonine-protein kinase B-...2200.0000000004     67     24     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.
578P41243    467   MATK_RAT Megakaryocyte-associated tyrosine-pr...2250.0000000004     66.6     23     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
579P20911    352   CDK7_XENLA Cyclin-dependent kinase 7 OS=Xenop...2270.0000000004     65.9     25     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.
580Q54XQ2    1125   RCKA_DICDI RGS domain-containing serine/threo...2740.0000000004     67.4     21     43GO:0005737; C:cytoplasm; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007189; P:activation of adenylate cyclase activity by G-protein signaling pathway; IGI:dictyBase.::GO:0007275; P:multicellular organismal development; IMP:dictyBase.::GO:0050921; P:positive regulation of chemotaxis; IMP:dictyBase.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
581Q9P0L2    795   MARK1_HUMAN Serine/threonine-protein kinase M...2030.0000000004     67     27     45GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.::GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
582P05625    647   RAF1_CHICK RAF proto-oncogene serine/threonin...2830.0000000004     67     25     46GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
583P50613    346   CDK7_HUMAN Cyclin-dependent kinase 7 OS=Homo ...2270.0000000005     65.9     26     45GO:0005675; C:holo TFIIH complex; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0008094; F:DNA-dependent ATPase activity; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0007050; P:cell cycle arrest; TAS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0006370; P:mRNA capping; TAS:Reactome.::GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.::GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.::GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
584P53599    1579   SSK2_YEAST MAP kinase kinase kinase SSK2 OS=S...3000.0000000005     67.4     21     43GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005829; C:cytosol; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030036; P:actin cytoskeleton organization; IDA:SGD.::GO:0000161; P:MAPK cascade involved in osmosensory signaling pathway; IMP:SGD.::GO:0007234; P:osmosensory signaling pathway via two-component system; IPI:SGD.::GO:0046777; P:protein autophosphorylation; IDA:SGD.
585Q60670    779   SIK1_MOUSE Serine/threonine-protein kinase SI...2320.0000000005     67     25     45GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008140; F:cAMP response element binding protein binding; IDA:UniProtKB.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0043276; P:anoikis; IMP:BHF-UCL.::GO:0055007; P:cardiac muscle cell differentiation; IMP:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0032792; P:negative regulation of CREB transcription factor activity; IDA:UniProtKB.::GO:0045721; P:negative regulation of gluconeogenesis; IDA:UniProtKB.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0007346; P:regulation of mitotic cell cycle; IDA:UniProtKB.::GO:0010830; P:regulation of myotube differentiation; IDA:UniProtKB.::GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB.
586P47810    646   WEE1_MOUSE Wee1-like protein kinase OS=Mus mu...2500.0000000005     66.6     25     44GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030010; P:establishment of cell polarity; IMP:MGI.::GO:0000226; P:microtubule cytoskeleton organization; IMP:MGI.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0048812; P:neuron projection morphogenesis; IMP:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.
587P18460    806   FGFR3_CHICK Fibroblast growth factor receptor...2980.0000000005     67     22     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
588Q05609    821   CTR1_ARATH Serine/threonine-protein kinase CT...3150.0000000005     67     21     44GO:0005789; C:endoplasmic reticulum membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0071281; P:cellular response to iron ion; IEP:TAIR.::GO:0009873; P:ethylene mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009686; P:gibberellin biosynthetic process; IMP:TAIR.::GO:0010105; P:negative regulation of ethylene mediated signaling pathway; TAS:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:2000069; P:regulation of post-embryonic root development; IMP:TAIR.::GO:2000035; P:regulation of stem cell division; IMP:TAIR.::GO:0048510; P:regulation of timing of transition from vegetative to reproductive phase; IMP:TAIR.::GO:0009750; P:response to fructose stimulus; IMP:TAIR.::GO:0009744; P:response to sucrose stimulus; IMP:TAIR.::GO:0010182; P:sugar mediated signaling pathway; TAS:TAIR.
589Q2QMI0    454   CIPK4_ORYSJ CBL-interacting protein kinase 4 ...2440.0000000005     66.2     27     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
590Q03002    865   FRK1_YEAST Fatty acyl-CoA synthetase and RNA ...2010.0000000005     67     25     47GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
591P22182    812   FGFR1_XENLA Fibroblast growth factor receptor...3000.0000000005     67     22     44GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; ISS:UniProtKB.
GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
592P00531    380   MIL_AVIMH Serine/threonine-protein kinase-tra...2830.0000000005     65.9     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
593Q9C958    361   SRK2B_ARATH Serine/threonine-protein kinase S...2130.0000000005     65.9     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009651; P:response to salt stress; IDA:TAIR.
594Q7XQP4    359   SAPK7_ORYSJ Serine/threonine-protein kinase S...2830.0000000005     65.9     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
595Q4V862    376   CDK9A_XENLA Cyclin-dependent kinase 9-A OS=Xe...2230.0000000005     65.9     28     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
596Q9Z1Z1    1108   E2AK3_RAT Eukaryotic translation initiation f...1960.0000000005     67     27     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; ISS:UniProtKB.
GO:0031018; P:endocrine pancreas development; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0006983; P:ER overload response; ISS:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; TAS:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
597Q16975    743   KPC2_APLCA Calcium-independent protein kinase...2730.0000000005     66.6     23     41GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
598C0LGD6    852   Y1570_ARATH Probable LRR receptor-like serine...2140.0000000005     67     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
599Q501V0    422   KPSH1_DANRE Serine/threonine-protein kinase H...3020.0000000005     65.9     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
600Q61161    821   M4K2_MOUSE Mitogen-activated protein kinase k...3070.0000000005     66.6     23     47GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0006903; P:vesicle targeting; IDA:UniProtKB.
601P50527    658   STE20_SCHPO Serine/threonine-protein kinase s...2260.0000000005     66.6     26     48GO:0071521; C:Cdc42 GTPase complex; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0032488; P:Cdc42 protein signal transduction; IGI:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; TAS:PomBase.::GO:0061161; P:positive regulation of establishment of bipolar cell polarity regulating cell shape; IGI:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.::GO:0070507; P:regulation of microtubule cytoskeleton organization; IGI:PomBase.
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