Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL095W
Length:
810
Number of sequences:
5887
Description:
YIL095W PRK1 SGDID:S000001357, Chr IX from 183937-186369, Genome Release 64-1-1, Verified ORF, "Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton and reduces endocytic ability of cell through the phosphorylation of the Pan1p-Sla1p-End3p protein complex"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
481A8X0C4    649   PAR4_CAEBR Serine/threonine-protein kinase pa...2410.0000000001     68.9     24     47GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
482O22187    834   Y2232_ARATH Probable receptor-like protein ki...2120.0000000001     68.9     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
483P42685    505   FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo...2700.0000000001     68.6     23     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
484Q9ZRF9    540   RPK1_ARATH Probable LRR receptor-like serine/...2110.0000000001     68.6     26     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0048508; P:embryonic meristem development; IMP:UniProtKB.::GO:0009942; P:longitudinal axis specification; IMP:UniProtKB.::GO:0009945; P:radial axis specification; IMP:UniProtKB.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009651; P:response to salt stress; IEP:UniProtKB.::GO:0009414; P:response to water deprivation; IEP:UniProtKB.
485Q6YY75    534   NEK6_ORYSJ Serine/threonine-protein kinase Ne...2150.0000000001     68.6     22     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
486Q9LHI7    571   NEK7_ARATH Serine/threonine-protein kinase Ne...2220.0000000001     68.6     24     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
487Q924X7    491   STK33_MOUSE Serine/threonine-protein kinase 3...2880.0000000001     68.2     22     42GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
488Q61851    801   FGFR3_MOUSE Fibroblast growth factor receptor...3050.0000000001     68.9     24     43GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; ISS:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0070977; P:bone maturation; IMP:BHF-UCL.::GO:0048640; P:negative regulation of developmental growth; IMP:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0010518; P:positive regulation of phospholipase activity; ISS:UniProtKB.::GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; ISS:UniProtKB.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.::GO:0035121; P:tail morphogenesis; IMP:BHF-UCL.
489A7MBB4    966   M3K13_BOVIN Mitogen-activated protein kinase ...2380.0000000001     68.9     24     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; IEA:InterPro.
GO:0046777; P:protein autophosphorylation; IEA:InterPro.
490Q21017    822   KIN29_CAEEL Serine/threonine-protein kinase k...2400.0000000001     68.9     26     46GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0043053; P:dauer entry; IMP:WormBase.::GO:0050907; P:detection of chemical stimulus involved in sensory perception; IMP:WormBase.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; TAS:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0046777; P:protein autophosphorylation; IDA:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IGI:WormBase.
491Q09831    566   PPK14_SCHPO Serine/threonine-protein kinase p...2070.0000000001     68.6     27     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0019236; P:response to pheromone; ISS:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
492P21802    821   FGFR2_HUMAN Fibroblast growth factor receptor...2960.0000000001     68.6     23     45GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; ISS:UniProtKB.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; IDA:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IDA:UniProtKB.::GO:0008201; F:heparin binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0030282; P:bone mineralization; ISS:UniProtKB.::GO:0060349; P:bone morphogenesis; ISS:UniProtKB.::GO:0060667; P:branch elongation involved in salivary gland morphogenesis; ISS:UniProtKB.::GO:0060670; P:branching involved in embryonic placenta morphogenesis; ISS:UniProtKB.::GO:0048755; P:branching morphogenesis of a nerve; ISS:UniProtKB.::GO:0060449; P:bud elongation involved in lung branching; ISS:UniProtKB.::GO:0045165; P:cell fate commitment; ISS:UniProtKB.::GO:0007267; P:cell-cell signaling; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.::GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; ISS:UniProtKB.::GO:0035603; P:fibroblast growth factor receptor signaling pathway involved in hemopoiesis; ISS:UniProtKB.::GO:0060595; P:fibroblast growth factor receptor signaling pathway involved in mammary gland specification; ISS:UniProtKB.::GO:0035602; P:fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow; ISS:UniProtKB.::GO:0035607; P:fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development; ISS:UniProtKB.::GO:0035604; P:fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow; ISS:UniProtKB.::GO:0031069; P:hair follicle morphogenesis; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0032808; P:lacrimal gland development; ISS:UniProtKB.::GO:0060601; P:lateral sprouting from an epithelium; ISS:UniProtKB.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0048286; P:lung alveolus development; ISS:UniProtKB.::GO:0060463; P:lung lobe morphogenesis; ISS:UniProtKB.::GO:0060484; P:lung-associated mesenchyme development; ISS:UniProtKB.::GO:0060615; P:mammary gland bud formation; ISS:UniProtKB.::GO:0003149; P:membranous septum morphogenesis; ISS:UniProtKB.::GO:0060915; P:mesenchymal cell differentiation involved in lung development; ISS:UniProtKB.::GO:0060916; P:mesenchymal cell proliferation involved in lung development; ISS:UniProtKB.::GO:0030901; P:midbrain development; ISS:UniProtKB.::GO:0035264; P:multicellular organism growth; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042476; P:odontogenesis; ISS:UniProtKB.::GO:0035265; P:organ growth; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0003148; P:outflow tract septum morphogenesis; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051781; P:positive regulation of cell division; ISS:UniProtKB.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:0010518; P:positive regulation of phospholipase activity; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB.::GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; ISS:UniProtKB.::GO:0060523; P:prostate epithelial cord elongation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0021860; P:pyramidal neuron development; ISS:UniProtKB.::GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; ISS:UniProtKB.::GO:0010453; P:regulation of cell fate commitment; ISS:UniProtKB.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; TAS:UniProtKB.::GO:0033688; P:regulation of osteoblast proliferation; TAS:UniProtKB.::GO:0051150; P:regulation of smooth muscle cell differentiation; ISS:UniProtKB.::GO:0008589; P:regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0060529; P:squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; ISS:UniProtKB.::GO:0001657; P:ureteric bud development; ISS:UniProtKB.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:UniProtKB.::GO:0021847; P:ventricular zone neuroblast division; ISS:UniProtKB.
493Q8IWU2    1503   LMTK2_HUMAN Serine/threonine-protein kinase L...3310.0000000001     68.9     24     43GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0055037; C:recycling endosome; IDA:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0070853; F:myosin VI binding; IPI:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.::GO:0032456; P:endocytic recycling; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0001881; P:receptor recycling; IMP:UniProtKB.::GO:0033572; P:transferrin transport; IMP:UniProtKB.
494P16054    737   KPCE_MOUSE Protein kinase C epsilon type OS=M...2790.0000000001     68.6     23     40GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0071889; F:14-3-3 protein binding; IPI:UniProtKB.::GO:0003785; F:actin monomer binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004699; F:calcium-independent protein kinase C activity; IDA:MGI.::GO:0035276; F:ethanol binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030546; F:receptor activator activity; IDA:MGI.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071361; P:cellular response to ethanol; IGI:MGI.::GO:0071456; P:cellular response to hypoxia; IDA:MGI.::GO:0007635; P:chemosensory behavior; TAS:MGI.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.::GO:0035641; P:locomotory exploration behavior; IGI:MGI.::GO:0002281; P:macrophage activation involved in immune response; IMP:MGI.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0010811; P:positive regulation of cell-substrate adhesion; IMP:MGI.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0010763; P:positive regulation of fibroblast migration; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0032024; P:positive regulation of insulin secretion; IMP:MGI.::GO:0050996; P:positive regulation of lipid catabolic process; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI.::GO:0070257; P:positive regulation of mucus secretion; IMP:MGI.::GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IMP:MGI.::GO:0090303; P:positive regulation of wound healing; ISS:UniProtKB.::GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IMP:MGI.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0051209; P:release of sequestered calcium ion into cytosol; IMP:MGI.::GO:0043278; P:response to morphine; IMP:MGI.::GO:0035669; P:TRAM-dependent toll-like receptor 4 signaling pathway; IMP:UniProtKB.
495O70405    1051   ULK1_MOUSE Serine/threonine-protein kinase UL...2490.0000000001     68.9     24     42GO:0030659; C:cytoplasmic vesicle membrane; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB.::GO:0070969; C:ULK1-ATG13-FIP200 complex; IPI:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0000045; P:autophagic vacuole assembly; IMP:UniProtKB.::GO:0048675; P:axon extension; IMP:MGI.::GO:0021707; P:cerebellar granule cell differentiation; IMP:MGI.::GO:0048671; P:negative regulation of collateral sprouting; IMP:MGI.::GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0008104; P:protein localization; ISS:UniProtKB.::GO:0021933; P:radial glia guided migration of cerebellar granule cell; IMP:MGI.::GO:0007265; P:Ras protein signal transduction; IDA:MGI.::GO:0031623; P:receptor internalization; IMP:MGI.::GO:0051386; P:regulation of nerve growth factor receptor signaling pathway; IMP:MGI.
496Q9WTQ0    707   KPCT_RAT Protein kinase C theta type OS=Rattu...2870.0000000001     68.6     21     42GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0031594; C:neuromuscular junction; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0042383; C:sarcolemma; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0007568; P:aging; IEP:RGD.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0070233; P:negative regulation of T cell apoptotic process; ISS:UniProtKB.::GO:0030182; P:neuron differentiation; IEP:RGD.::GO:0051491; P:positive regulation of filopodium assembly; IMP:RGD.::GO:0032740; P:positive regulation of interleukin-17 production; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IMP:RGD.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0050714; P:positive regulation of protein secretion; IDA:RGD.::GO:0051496; P:positive regulation of stress fiber assembly; IMP:RGD.::GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:UniProtKB.::GO:2000570; P:positive regulation of T-helper 2 cell activation; ISS:UniProtKB.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:RGD.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0019229; P:regulation of vasoconstriction; IEP:RGD.::GO:0045730; P:respiratory burst; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0042246; P:tissue regeneration; IEP:RGD.
497P38991    367   IPL1_YEAST Spindle assembly checkpoint kinase...2030.0000000001     67.4     29     44GO:0032133; C:chromosome passenger complex; IDA:SGD.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005828; C:kinetochore microtubule; IDA:SGD.::GO:0051233; C:spindle midzone; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0008608; P:attachment of spindle microtubules to kinetochore; IMP:SGD.::GO:0045143; P:homologous chromosome segregation; IMP:SGD.::GO:0045144; P:meiotic sister chromatid segregation; IMP:SGD.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IGI:SGD.::GO:0051228; P:mitotic spindle disassembly; IMP:SGD.::GO:0032465; P:regulation of cytokinesis; IMP:SGD.::GO:0031577; P:spindle checkpoint; IMP:SGD.
498P0A5S4    626   PKNB_MYCTU Serine/threonine-protein kinase pk...1410.0000000002     68.2     30     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030145; F:manganese ion binding; IDA:MTBBASE.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MTBBASE.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE.
GO:0040007; P:growth; IMP:MTBBASE.::GO:0043086; P:negative regulation of catalytic activity; IDA:MTBBASE.::GO:0032091; P:negative regulation of protein binding; IDA:MTBBASE.::GO:0043085; P:positive regulation of catalytic activity; IDA:MTBBASE.::GO:0043388; P:positive regulation of DNA binding; IDA:MTBBASE.::GO:0046777; P:protein autophosphorylation; IDA:MTBBASE.::GO:0008360; P:regulation of cell shape; IMP:MTBBASE.::GO:0051338; P:regulation of transferase activity; IDA:MTBBASE.::GO:0052572; P:response to host immune response; IDA:MTBBASE.
499P0A5S5    626   PKNB_MYCBO Serine/threonine-protein kinase pk...1410.0000000002     68.2     30     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
500Q8VDU5    748   SNRK_MOUSE SNF-related serine/threonine-prote...2860.0000000002     68.6     27     45GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
501Q91287    796   FGFR3_PLEWA Fibroblast growth factor receptor...3000.0000000002     68.6     22     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
502O01700    928   DLK1_CAEEL Mitogen-activated protein kinase k...1830.0000000002     68.6     28     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0045202; C:synapse; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:WormBase.
GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0050807; P:regulation of synapse organization; IGI:WormBase.
503P53104    897   ATG1_YEAST Serine/threonine-protein kinase AT...3120.0000000002     68.6     22     42GO:0034273; C:Atg1p signaling complex; IPI:SGD.::GO:0005829; C:cytosol; IDA:SGD.::GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IMP:SGD.
GO:0000045; P:autophagic vacuole assembly; IMP:SGD.::GO:0032258; P:CVT pathway; IMP:SGD.::GO:0000422; P:mitochondrion degradation; IMP:SGD.::GO:0034727; P:piecemeal microautophagy of nucleus; IMP:SGD.
504A6ZU07    897   ATG1_YEAS7 Serine/threonine-protein kinase AT...3120.0000000002     68.6     22     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
505Q9KIG4    641   PK1_STRTO Serine/threonine-protein kinase PK-...1960.0000000002     68.2     29     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
506Q97IC2    657   PKN2_CLOAB Probable serine/threonine-protein ...2960.0000000002     68.2     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
507P18461    823   FGFR2_CHICK Fibroblast growth factor receptor...2960.0000000002     68.6     23     45GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
508Q10056    589   SHK2_SCHPO Serine/threonine-protein kinase sh...2570.0000000002     68.2     25     46GO:0005739; C:mitochondrion; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0032488; P:Cdc42 protein signal transduction; NAS:PomBase.::GO:0000165; P:MAPK cascade; NAS:PomBase.
509Q9LDI3    446   CIPKO_ARATH CBL-interacting serine/threonine-...2660.0000000002     67.8     27     46GO:0009705; C:plant-type vacuole membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
510Q02111    707   KPCT_MOUSE Protein kinase C theta type OS=Mus...2870.0000000002     68.2     21     42GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001772; C:immunological synapse; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004697; F:protein kinase C activity; IDA:MGI.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0006509; P:membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0070233; P:negative regulation of T cell apoptotic process; ISS:UniProtKB.::GO:0032740; P:positive regulation of interleukin-17 production; IMP:UniProtKB.::GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IMP:MGI.::GO:0032753; P:positive regulation of interleukin-4 production; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:2000318; P:positive regulation of T-helper 17 type immune response; IMP:UniProtKB.::GO:2000570; P:positive regulation of T-helper 2 cell activation; IMP:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; IMP:UniProtKB.
511D3ZBE5    302   NEK7_RAT Serine/threonine-protein kinase Nek7...2910.0000000002     66.6     26     45GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
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