Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL094C
Length:
371
Number of sequences:
5887
Description:
YIL094C LYS12 SGDID:S000001356, Chr IX from 187632-186517, Genome Release 64-1-1, reverse complement, Verified ORF, "Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q2P762    357   LEU3_XANOM 3-isopropylmalate dehydrogenase OS...3543e-51     181     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
62Q21XI1    356   LEU3_RHOFD 3-isopropylmalate dehydrogenase OS...3593e-51     180     37     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
63Q65V05    358   LEU3_MANSM 3-isopropylmalate dehydrogenase OS...3494e-51     180     36     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
64Q3APC4    352   LEU3_CHLCH 3-isopropylmalate dehydrogenase OS...3614e-51     180     34     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
65Q31B91    357   LEU3_PROM9 3-isopropylmalate dehydrogenase OS...3625e-51     180     38     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
66Q8DTG3    344   LEU3_STRMU 3-isopropylmalate dehydrogenase OS...3637e-51     179     37     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
67Q30RK2    355   LEU3_SULDN 3-isopropylmalate dehydrogenase OS...3477e-51     179     37     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
68Q884C0    360   LEU3_PSESM 3-isopropylmalate dehydrogenase OS...3758e-51     179     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
69P93032    367   IDH2_ARATH Isocitrate dehydrogenase [NAD] reg...3609e-51     179     35     56GO:0005739; C:mitochondrion; IDA:TAIR.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; TAS:TAIR.
70P28834    360   IDH1_YEAST Isocitrate dehydrogenase [NAD] sub...3721e-50     179     34     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005758; C:mitochondrial intermembrane space; TAS:Reactome.::GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IDA:SGD.::GO:0042645; C:mitochondrial nucleoid; IDA:SGD.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006537; P:glutamate biosynthetic process; TAS:SGD.::GO:0006102; P:isocitrate metabolic process; TAS:SGD.::GO:0006099; P:tricarboxylic acid cycle; TAS:SGD.
71Q51375    360   LEU3_PSEAE 3-isopropylmalate dehydrogenase OS...3681e-50     179     35     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
72Q7VC80    362   LEU3_PROMA 3-isopropylmalate dehydrogenase OS...3581e-50     179     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
73Q7NUC2    354   LEU3_CHRVO 3-isopropylmalate dehydrogenase OS...3462e-50     178     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
74Q3B595    353   LEU3_PELLD 3-isopropylmalate dehydrogenase OS...3612e-50     178     34     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
75Q5WEN4    364   LEU3_BACSK 3-isopropylmalate dehydrogenase OS...3572e-50     178     38     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
76O67480    426   IDH_AQUAE Isocitrate dehydrogenase [NADP] OS=...3694e-50     179     36     52
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
77Q7M886    358   LEU3_WOLSU 3-isopropylmalate dehydrogenase OS...3515e-50     177     36     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
78P43860    358   LEU3_HAEIN 3-isopropylmalate dehydrogenase OS...3505e-50     177     37     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
79Q9FMT1    409   LEU33_ARATH 3-isopropylmalate dehydrogenase 3...3836e-50     178     35     53GO:0009570; C:chloroplast stroma; IDA:TAIR.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IGI:TAIR.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0019761; P:glucosinolate biosynthetic process; IMP:TAIR.::GO:0009098; P:leucine biosynthetic process; IGI:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
80Q7VH33    357   LEU3_HELHP 3-isopropylmalate dehydrogenase OS...3387e-50     177     37     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
81Q97EE2    357   LEU3_CLOAB 3-isopropylmalate dehydrogenase OS...3428e-50     176     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
82Q63DX7    354   LEU3_BACCZ 3-isopropylmalate dehydrogenase OS...3571e-49     176     37     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
83Q9PAX3    357   LEU3_XYLFA 3-isopropylmalate dehydrogenase OS...3511e-49     176     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
84P28241    369   IDH2_YEAST Isocitrate dehydrogenase [NAD] sub...3601e-49     176     35     52GO:0005962; C:mitochondrial isocitrate dehydrogenase complex (NAD+); IDA:SGD.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006537; P:glutamate biosynthetic process; TAS:SGD.::GO:0006102; P:isocitrate metabolic process; TAS:SGD.::GO:0006099; P:tricarboxylic acid cycle; TAS:SGD.
85Q2S0M8    365   LEU3_SALRD 3-isopropylmalate dehydrogenase OS...3461e-49     176     37     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
86Q7U840    357   LEU3_SYNPX 3-isopropylmalate dehydrogenase OS...3482e-49     176     35     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
87Q7UIE1    359   LEU3_RHOBA 3-isopropylmalate dehydrogenase OS...3522e-49     175     36     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
88Q73B99    354   LEU3_BACC1 3-isopropylmalate dehydrogenase OS...3573e-49     175     37     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
89Q393X4    355   LEU3_BURS3 3-isopropylmalate dehydrogenase OS...3713e-49     175     37     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
90P29102    406   LEU3_BRANA 3-isopropylmalate dehydrogenase, c...3604e-49     176     36     53GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
91Q4L7U1    346   LEU3_STAHJ 3-isopropylmalate dehydrogenase OS...3595e-49     174     35     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003862; F:3-isopropylmalate dehydrogenase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
records
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