Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YIL094C
Length:
371
Number of sequences:
5887
Description:
YIL094C LYS12 SGDID:S000001356, Chr IX from 187632-186517, Genome Release 64-1-1, reverse complement, Verified ORF, "Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
391Q75JR3    412   IDHC_DICDI Isocitrate dehydrogenase [NADP] cy...1040.000002     53.1     32     53GO:0005829; C:cytosol; ISS:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
392O75874    414   IDHC_HUMAN Isocitrate dehydrogenase [NADP] cy...1280.000002     52.8     31     52GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005782; C:peroxisomal matrix; TAS:Reactome.
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
GO:0006103; P:2-oxoglutarate metabolic process; IDA:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; IDA:UniProtKB.::GO:0006740; P:NADPH regeneration; TAS:Reactome.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
393Q5R9C5    414   IDHC_PONAB Isocitrate dehydrogenase [NADP] cy...1280.000002     52.8     31     52
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
394Q9Z2K9    414   IDHC_MICME Isocitrate dehydrogenase [NADP] cy...1280.000003     52.4     30     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
395Q9Z2K8    414   IDHC_MICOH Isocitrate dehydrogenase [NADP] cy...1280.000003     52.4     30     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
396P53982    420   IDHH_YEAST Isocitrate dehydrogenase [NADP] OS...2190.000003     52.4     25     44GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005777; C:peroxisome; IDA:SGD.
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; TAS:SGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006635; P:fatty acid beta-oxidation; IMP:SGD.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; TAS:SGD.::GO:0006740; P:NADPH regeneration; TAS:SGD.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
397Q6XUZ5    414   IDHC_SHEEP Isocitrate dehydrogenase [NADP] cy...1280.000004     52     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
398O13285    430   IDH1_CANTR Isocitrate dehydrogenase [NADP], m...1070.000004     52     31     55GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
399O88844    414   IDHC_MOUSE Isocitrate dehydrogenase [NADP] cy...1280.000006     51.6     30     52GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.::GO:0006749; P:glutathione metabolic process; IMP:MGI.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IDA:MGI.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
400P41939    412   IDHC_YEAST Isocitrate dehydrogenase [NADP] cy...2180.00001     50.4     27     46GO:0005829; C:cytosol; IDA:SGD.
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; TAS:SGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006537; P:glutamate biosynthetic process; TAS:SGD.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; IMP:SGD.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
401Q75JR2    428   IDHP_DICDI Isocitrate dehydrogenase [NADP], m...1050.00006     48.5     31     51GO:0005739; C:mitochondrion; ISS:dictyBase.
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
402Q9LQK9    294   IDH4_ARATH Putative isocitrate dehydrogenase ...2600.00007     47.8     26     43
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
403O13294    411   IDH2_CANTR Isocitrate dehydrogenase [NADP] pe...2080.00008     47.8     27     46GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
404P65097    409   IDH_MYCTU Isocitrate dehydrogenase [NADP] OS=...1370.012     41.2     28     47GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IDA:MTBBASE.::GO:0000287; F:magnesium ion binding; IDA:MTBBASE.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:MTBBASE.::GO:0008270; F:zinc ion binding; IDA:MTBBASE.
GO:0006097; P:glyoxylate cycle; IDA:MTBBASE.::GO:0006102; P:isocitrate metabolic process; IDA:MTBBASE.::GO:0006099; P:tricarboxylic acid cycle; IDA:MTBBASE.
405P65098    409   IDH_MYCBO Isocitrate dehydrogenase [NADP] OS=...1370.012     41.2     28     47
GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006102; P:isocitrate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
406B7KAA8    343   PDXA_CYAP7 4-hydroxythreonine-4-phosphate deh...630.65     35.4     35     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050570; F:4-hydroxythreonine-4-phosphate dehydrogenase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0008615; P:pyridoxine biosynthetic process; IEA:UniProtKB-KW.
407P56472    103   IDH3B_PIG Isocitrate dehydrogenase [NAD] subu...961.7     32.3     25     44GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
408P86225    134   IDH3A_MESAU Isocitrate dehydrogenase [NAD] su...492     32.7     39     57GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
409C0QTA7    319   PDXA_PERMH 4-hydroxythreonine-4-phosphate deh...662.3     33.9     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050570; F:4-hydroxythreonine-4-phosphate dehydrogenase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0008615; P:pyridoxine biosynthetic process; IEA:UniProtKB-KW.
410Q164G2    326   PDXA_ROSDO 4-hydroxythreonine-4-phosphate deh...273.1     33.5     59     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050570; F:4-hydroxythreonine-4-phosphate dehydrogenase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0008615; P:pyridoxine biosynthetic process; IEA:UniProtKB-KW.
411A3QH80    562   MAO1_SHELP NAD-dependent malic enzyme OS=Shew...986.4     32.7     23     43
GO:0016619; F:malate dehydrogenase (oxaloacetate-decarboxylating) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0006108; P:malate metabolic process; IEA:InterPro.
412B2V9E6    322   PDXA_SULSY 4-hydroxythreonine-4-phosphate deh...747.2     32.3     31     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050570; F:4-hydroxythreonine-4-phosphate dehydrogenase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0008615; P:pyridoxine biosynthetic process; IEA:UniProtKB-KW.
records
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